Protein: CDC7
Cell division control protein 7 (EC 2.7.11.1)

Gene: CDC7
Organism: Saccharomyces cerevisiae S288C
Interactions: 127
UniProt ID: P06243

Gene Ontology (top 5):
GO:0000727 - double-strand break repair via break-induced replication
GO:0000775 - chromosome, centromeric region
GO:0000785 - chromatin
GO:0001100 - negative regulation of exit from mitosis
GO:0004674 - protein serine/threonine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

440915

DBF4
DDK kinase regulatory subunit DBF4

29

3

Small-scale

0.993

High

440876

CDC7
Cell division control protein 7

4

18

Small-scale

0.905

High

440898

RAD53
Serine/threonine-protein kinase RAD53

3

20

Small-scale

0.867

High

440919

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

3

19

Small-scale

0.855

High

440909

MCM2
DNA replication licensing factor MCM2

14

20

Small-scale

0.762

High

440912

MCM4
DNA replication licensing factor MCM4

11

20

Small-scale

0.757

High

440957

MCM6
DNA replication licensing factor MCM6

7

20

Small-scale

0.744

High

438176

CDC37
Hsp90 co-chaperone Cdc37

1

20

Small-scale

0.656

High

440955

BIR1
Chromosomal passenger complex protein BIR1

1

0

High-throughput

0.656

High

440899

MCM3
DNA replication licensing factor MCM3

3

20

Small-scale

0.651

High

364228

CDK1
Cyclin-dependent kinase 1

1

18

Small-scale

0.647

High

391990

HSP82
ATP-dependent molecular chaperone HSP82

1

20

High-throughput

0.646

High

440900

SCJ1
DnaJ-related protein SCJ1

1

15

High-throughput

0.646

High

440902

MAS5
Mitochondrial protein import protein MAS5

1

19

High-throughput

0.646

High

440964

ACT
Actin

1

14

High-throughput

0.646

High

440910

MCM5
Minichromosome maintenance protein 5

2

20

Small-scale

0.625

High

440933

RT107
Regulator of Ty1 transposition protein 107

2

4

Small-scale

0.620

High

440882

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

20

High-throughput

0.618

High

440918

HOG1
Mitogen-activated protein kinase HOG1

1

19

Small-scale

0.618

High

440916

MCM10
Minichromosome maintenance protein 10

2

5

Small-scale

0.602

High

440988

CAF1A
Chromatin assembly factor 1 subunit A

2

10

Small-scale

0.602

High

440979

CDC53
Cell division control protein 53

2

20

Small-scale

0.595

High

440929

MCM7
DNA replication licensing factor MCM7

2

20

Small-scale

0.594

High

440947

DSN1
Kinetochore-associated protein DSN1

2

3

High-throughput

0.584

High

440966

PRS8
26S proteasome regulatory subunit 8 homolog

2

20

Small-scale

0.584

High

440920

RPN2
26S proteasome regulatory subunit RPN2

1

11

Small-scale

0.575

High

440928

CENPA
Histone H3-like centromeric protein CSE4

1

20

Small-scale

0.561

High

440948

MSH4
MutS protein homolog 4

1

6

Small-scale

0.561

High

440936

REV7
DNA polymerase zeta processivity subunit

1

0

Small-scale

0.537

High

440891

STI1
Heat shock protein STI1

1

17

High-throughput

0.536

High

440893

PDC5
Pyruvate decarboxylase isozyme 2

1

5

High-throughput

0.536

High

440906

PDC6
Pyruvate decarboxylase isozyme 3

1

5

High-throughput

0.536

High

440907

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

2

High-throughput

0.536

High

440939

HSP7E
Heat shock protein SSC3, mitochondrial

1

20

High-throughput

0.536

High

440965

TPS1
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit

1

6

High-throughput

0.536

High

440970

KYNU
Kynureninase

1

1

High-throughput

0.536

High

440976

THI3
Thiamine metabolism regulatory protein THI3

1

5

High-throughput

0.536

High

440985

PST2
Protoplast secreted protein 2

1

2

High-throughput

0.536

High

440969

LRS4
Monopolin complex subunit LRS4

1

1

Small-scale

0.515

High

440917

HYM1
Protein HYM1

1

1

Small-scale

0.514

High

440967

CENPP
Inner kinetochore subunit CTF19

1

0

Small-scale

0.513

High

440958

MED5
Mediator of RNA polymerase II transcription subunit 5

1

0

High-throughput

0.513

High

440938

DHH1
ATP-dependent RNA helicase DHH1

1

20

High-throughput

0.508

High

440913

ZIP1
Synaptonemal complex protein ZIP1

1

20

Small-scale

0.501

High

440926

SLD2
DNA replication regulator SLD2

1

2

Small-scale

0.501

High

440927

CENPC
Inner kinetochore subunit MIF2

1

1

Small-scale

0.501

High

440942

RT106
Histone chaperone RTT106

1

1

Small-scale

0.501

High

440951

ECO1
N-acetyltransferase ECO1

1

2

Small-scale

0.501

High

440953

COM1
DNA endonuclease SAE2

1

1

Small-scale

0.501

High

440954

EAF6
Chromatin modification-related protein EAF6

1

2

High-throughput

0.501

High

366871

ATPB
ATP synthase subunit beta, mitochondrial

1

16

High-throughput

0.500

High

386511

TBB
Tubulin beta chain

1

20

High-throughput

0.500

High

394097

EF1A
Elongation factor 1-alpha

1

8

High-throughput

0.500

High

408263

GAL1
Galactokinase

1

2

High-throughput

0.500

High

440877

ATPA
ATP synthase subunit alpha, mitochondrial

1

15

High-throughput

0.500

High

440879

TBA1
Tubulin alpha-1 chain

1

19

High-throughput

0.500

High

440880

TBA3
Tubulin alpha-3 chain

1

19

High-throughput

0.500

High

440892

VATB
V-type proton ATPase subunit B

1

17

High-throughput

0.500

High

440895

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

6

High-throughput

0.500

High

440896

HSP60
Heat shock protein 60, mitochondrial

1

20

High-throughput

0.500

High

440905

CDC48
Cell division control protein 48

1

11

High-throughput

0.500

High

440977

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

1

High-throughput

0.500

High

440978

THI21
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI21

1

1

High-throughput

0.500

High

440984

HSP42
Heat shock protein 42

1

3

High-throughput

0.500

High

440987

RUVB2
RuvB-like protein 2

1

8

High-throughput

0.500

High

440897

SAR1
Small COPII coat GTPase SAR1

1

11

High-throughput

0.489

High

440949

COPB2
Coatomer subunit beta'

1

10

High-throughput

0.489

High

440973

BFR2
Protein BFR2

1

1

High-throughput

0.489

High

440956

TEL2
Telomere length regulation protein TEL2

1

0

High-throughput

0.486

High

440981

TSR3
18S rRNA aminocarboxypropyltransferase

1

0

High-throughput

0.486

High

440921

ORC2
Origin recognition complex subunit 2

1

7

Small-scale

0.481

High

440911

RIF1
Telomere length regulator protein RIF1

1

0

Small-scale

0.480

High

440974

CENPO
Inner kinetochore subunit MCM21

1

0

Small-scale

0.480

High

440989

CENPI
Inner kinetochore subunit CTF3

1

0

Small-scale

0.480

High

440908

TF2B
Transcription initiation factor IIB

1

5

High-throughput

0.479

High

440930

MMS4
Crossover junction endonuclease MMS4

1

1

Small-scale

0.479

High

440959

NMA2
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2

1

1

High-throughput

0.479

High

440962

NAT10
RNA cytidine acetyltransferase

1

2

High-throughput

0.479

High

440968

SCC2
Sister chromatid cohesion protein 2

1

4

High-throughput

0.479

High

440980

MLH3
DNA mismatch repair protein MLH3

1

2

High-throughput

0.479

High

440971

CORO
Coronin-like protein

1

6

High-throughput

0.470

High

425090

OTC
Ornithine carbamoyltransferase

1

7

High-throughput

0.464

High

440937

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.458

High

440945

SPO22
Sporulation-specific protein 22

1

0

Small-scale

0.458

High

440963

ORC3
Origin recognition complex subunit 3

1

0

Small-scale

0.458

High

440972

NOC4
Nucleolar complex protein 4

1

0

Small-scale

0.458

High

440943

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

15

High-throughput

0.457

High

404996

LEU3
3-isopropylmalate dehydrogenase

1

11

High-throughput

0.457

High

440888

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

4

High-throughput

0.457

High

440883

HSP77
Import motor subunit, mitochondrial

1

20

High-throughput

0.445

High

440884

IF4A
ATP-dependent RNA helicase eIF4A

1

20

Small-scale

0.445

High

440885

HSP71
Heat shock protein SSA1

1

20

High-throughput

0.445

High

440886

ARF1
ADP-ribosylation factor 1

1

7

Small-scale

0.445

High

440887

SSB1
Ribosome-associated molecular chaperone SSB1

1

20

High-throughput

0.445

High

440890

PP2B2
Serine/threonine-protein phosphatase 2B catalytic subunit A2

1

20

Small-scale

0.445

High

440894

BIP
Endoplasmic reticulum chaperone BiP

1

20

Small-scale

0.445

High

440923

PRS6A
26S proteasome regulatory subunit 6A

1

20

Small-scale

0.445

High

440924

PRS6B
26S proteasome regulatory subunit 6B homolog

1

17

Small-scale

0.445

High

440925

PRS7
26S proteasome regulatory subunit 7 homolog

1

20

Small-scale

0.445

High

440931

SDS24
Protein SDS24

1

3

Small-scale

0.445

High

440932

RPN1
26S proteasome regulatory subunit RPN1

1

12

Small-scale

0.445

High

440941

SSB2
Ribosome-associated molecular chaperone SSB2

1

20

High-throughput

0.445

High

440944

PRS4
26S proteasome regulatory subunit 4 homolog

1

20

Small-scale

0.445

High

440960

PRS10
26S proteasome subunit RPT4

1

20

Small-scale

0.445

High

150245

RPN13
26S proteasome regulatory subunit RPN13

1

0

Small-scale

0.426

High

440934

SSP1
Sporulation-specific protein 1

1

0

Small-scale

0.426

High

440935

ADY1
Prospore formation at selected spindle poles protein 1

1

0

Small-scale

0.426

High

440946

GVP36
Protein GVP36

1

0

Small-scale

0.426

High

440982

REC8
Meiotic recombination protein REC8

1

0

Small-scale

0.426

High

440986

MPC70
Sporulation-specific protein 21

1

0

Small-scale

0.426

High

440878

SPS2
Sporulation-specific protein 2

1

1

Small-scale

0.407

High

440889

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

3

Small-scale

0.407

High

440901

SPS22
Sporulation-specific protein 22

1

1

Small-scale

0.407

High

440950

SPR3
Sporulation-regulated protein 3

1

4

Small-scale

0.407

High

440975

VAC14
Vacuole morphology and inheritance protein 14

1

0

High-throughput

0.279

Low

440904

YCU0
Uncharacterized protein YCR050C

1

0

High-throughput

0.265

Low

440922

PTM1
Membrane protein PTM1

1

0

High-throughput

0.265

Low

440940

YEC3
Uncharacterized protein YEL023C

1

0

High-throughput

0.265

Low

440952

YFM7
Uncharacterized protein YFR057W

1

0

High-throughput

0.265

Low

440961

YN8S
Phospholipid-transporting ATPase accessory subunit CRF1

1

0

High-throughput

0.265

Low

150226

JIP3
Uncharacterized protein JIP3

1

0

High-throughput

0.261

Low

440990

EFG1P
rRNA-processing protein EFG1

1

0

High-throughput

0.249

Low

440903

YCR2
Uncharacterized protein YCR022C

1

0

High-throughput

0.238

Low

440881

SPS4
Sporulation-specific protein 4

1

0

Small-scale

0.232

Low

440914

LDS1
Outer spore wall protein LDS1

1

0

Small-scale

0.232

Low

440983

SPR2
Sorulation-regulated protein 2

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025