Protein: NSG1
Protein NSG1 (INSIG homolog 1)

Gene: NSG1
Organism: Saccharomyces cerevisiae S288C
Interactions: 51
UniProt ID: P38837

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
GO:0016126 - sterol biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

554425

HMDH2
3-hydroxy-3-methylglutaryl-coenzyme A reductase 2

4

1

Small-scale

0.898

High

554344

HMDH1
3-hydroxy-3-methylglutaryl-coenzyme A reductase 1

2

1

High-throughput

0.793

High

805790

ELO3
Fatty acid elongase 3

2

1

High-throughput

0.614

High

796917

PHO88
SRP-independent targeting protein 3

2

0

High-throughput

0.588

High

448717

SNF1
Carbon catabolite-derepressing protein kinase

2

0

High-throughput

0.577

High

416700

CAN1
Arginine permease CAN1

1

2

High-throughput

0.541

High

672801

ELO2
Fatty acid elongase 2

1

1

High-throughput

0.541

High

673421

AGP1
General amino acid permease AGP1

1

2

High-throughput

0.541

High

805806

SAM3
S-adenosylmethionine permease SAM3

1

2

High-throughput

0.541

High

598508

ALG1
Chitobiosyldiphosphodolichol beta-mannosyltransferase

1

0

High-throughput

0.518

High

672155

ERG4
Delta(24(24(1)))-sterol reductase ERG4

1

0

High-throughput

0.518

High

797383

MKAR
Very-long-chain 3-oxoacyl-CoA reductase

1

0

High-throughput

0.518

High

798709

BSD2
Metal homeostatis protein BSD2

1

0

High-throughput

0.518

High

798742

PHO89
Phosphate permease PHO89

1

0

High-throughput

0.518

High

805788

YHU0
UPF0641 membrane protein YHR140W

1

0

High-throughput

0.518

High

805791

ALG5
Dolichyl-phosphate beta-glucosyltransferase

1

0

High-throughput

0.518

High

805792

SNL1
HSP70 co-chaperone SNL1

1

0

High-throughput

0.518

High

805793

VNX1
Low affinity vacuolar monovalent cation/H(+) antiporter

1

0

High-throughput

0.518

High

805794

FET5
Iron transport multicopper oxidase FET5

1

0

High-throughput

0.518

High

805795

PHO86
Inorganic phosphate transporter PHO86

1

0

High-throughput

0.518

High

805797

GPI8
GPI-anchor transamidase

1

0

High-throughput

0.518

High

805802

OSTD
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1

1

0

High-throughput

0.518

High

805804

GSF2
Glucose-signaling factor 2

1

0

High-throughput

0.518

High

805807

YOP1
Protein YOP1

1

0

High-throughput

0.518

High

805809

ERP4
Protein ERP4

1

0

High-throughput

0.518

High

805811

TECR
Very-long-chain enoyl-CoA reductase

1

0

High-throughput

0.518

High

805803

GAS3
Probable 1,3-beta-glucanosyltransferase GAS3

1

1

High-throughput

0.494

High

805805

GAS2
1,3-beta-glucanosyltransferase GAS2

1

1

High-throughput

0.494

High

748837

SWE1
Mitosis inhibitor protein kinase SWE1

1

0

High-throughput

0.480

High

523889

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.479

High

726082

PMT2
Dolichyl-phosphate-mannose--protein mannosyltransferase 2

1

2

High-throughput

0.479

High

754684

PMT1
Dolichyl-phosphate-mannose--protein mannosyltransferase 1

1

2

High-throughput

0.479

High

805796

PMT4
Dolichyl-phosphate-mannose--protein mannosyltransferase 4

1

2

High-throughput

0.479

High

805799

SC6B1
Protein transport protein SBH1

1

0

Small-scale

0.460

High

748383

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.458

High

751697

PLSC
1-acyl-sn-glycerol-3-phosphate acyltransferase

1

0

High-throughput

0.458

High

754394

SEC66
Translocation protein SEC66

1

0

High-throughput

0.458

High

782203

GPT2
Glycerol-3-phosphate O-acyltransferase 2

1

0

High-throughput

0.458

High

802478

LAG1
Ceramide synthase LAG1

1

0

High-throughput

0.458

High

805789

SCS2
Vesicle-associated membrane protein-associated protein SCS2

1

0

High-throughput

0.458

High

805801

NOP3
Serine/arginine

1

0

High-throughput

0.458

High

805810

PGA3
Plasma membrane-associated coenzyme Q6 reductase PGA3

1

0

High-throughput

0.458

High

526652

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.445

High

486166

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.426

High

805808

LAS17
Proline-rich protein LAS17

2

0

High-throughput

0.307

High

613574

ADT2
ADP,ATP carrier protein 2

1

0

High-throughput

0.282

High

803018

ARN2
Siderophore iron transporter ARN2

1

0

High-throughput

0.282

High

805798

TOM22
Mitochondrial import receptor subunit TOM22

1

0

High-throughput

0.282

High

805800

PRM1
Plasma membrane fusion protein PRM1

1

0

High-throughput

0.282

High

365043

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.249

Low

758443

YKK0
Probable intramembrane protease YKL100C

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025