Protein: ISK5
Serine protease inhibitor Kazal-type 5 (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Cleaved into: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665]

Gene: ISK5, SPINK5
Organism: Homo sapiens
Interactions: 20
UniProt ID: Q9NQ38

Gene Ontology (top 5):
GO:0002787 - negative regulation of antibacterial peptide production
GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005576 - extracellular region
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1343116

KLK14
Kallikrein-14

2

8

Small-scale

0.754

High

1343118

KLK5
Kallikrein-5

2

7

Small-scale

0.754

High

1017606

FSTL1
Follistatin-related protein 1

1

6

High-throughput

0.691

High

1270143

TFG
Protein TFG

3

1

High-throughput

0.667

High

456946

FURIN
Furin

1

1

Small-scale

0.647

High

439369

CATG
Cathepsin G

1

15

Small-scale

0.618

High

836334

KLK7
Kallikrein-7

1

9

Small-scale

0.618

High

1343117

KLK13
Kallikrein-13

1

11

Small-scale

0.618

High

345552

FOS
Protein c-Fos

1

3

High-throughput

0.536

High

686751

CCR1
C-C chemokine receptor type 1

1

2

High-throughput

0.536

High

1218453

TEX14
Inactive serine/threonine-protein kinase TEX14

1

5

High-throughput

0.536

High

1198962

ISCA2
Iron-sulfur cluster assembly 2 homolog, mitochondrial

1

0

High-throughput

0.513

High

1255545

CGAT1
Chondroitin sulfate N-acetylgalactosaminyltransferase 1

1

0

High-throughput

0.513

High

818491

SOX2
Transcription factor SOX-2

1

2

High-throughput

0.479

High

1298208

ZDH15
Palmitoyltransferase ZDHHC15

1

4

Small-scale

0.479

High

946615

DCD
Dermcidin

1

0

Small-scale

0.458

High

683143

CASPE
Caspase-14

1

3

Small-scale

0.445

High

1159297

PRP8
Pre-mRNA-processing-splicing factor 8

1

1

High-throughput

0.437

High

1237195

PLD5
Inactive phospholipase D5

1

0

High-throughput

0.279

Low

1260920

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024