Protein: SEC4
Ras-related protein SEC4 (Suppressor of RHO3 protein 6)

Gene: SEC4
Organism: Saccharomyces cerevisiae S288C
Interactions: 100
UniProt ID: P07560

Gene Ontology (top 5):
GO:0000131 - incipient cellular bud site
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

429167

SEC2
Rab guanine nucleotide exchange factor SEC2

11

5

Small-scale

0.979

High

429168

MYO2
Myosin-2

6

10

Small-scale

0.956

High

429208

GDI1
Rab GDP-dissociation inhibitor

9

20

Small-scale

0.868

High

429225

GYP3
GTPase-activating protein GYP3

3

19

Small-scale

0.845

High

429185

DSS4
Protein DSS4

4

1

Small-scale

0.817

High

429188

RAEP
Rab proteins geranylgeranyltransferase component A

4

20

Small-scale

0.794

High

350833

YPT1
GTP-binding protein YPT1

2

18

High-throughput

0.789

High

429250

GYP1
GTPase-activating protein GYP1

2

19

Small-scale

0.778

High

429173

SEC15
Exocyst complex component SEC15

5

4

Small-scale

0.719

High

429251

SRO7
Lethal(2) giant larvae protein homolog SRO7

4

1

Small-scale

0.705

High

429244

GYL1
Probable GTPase-activating protein GYL1

1

14

High-throughput

0.698

High

429233

GYP2
GTPase-activating protein GYP2

2

18

Small-scale

0.696

High

429184

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

5

Small-scale

0.647

High

429254

MSB4
GTPase-activating protein MSB4

1

20

Small-scale

0.647

High

429197

BOB1
Protein BOB1

1

6

Small-scale

0.621

High

429209

BOI2
Protein BOI2

1

5

Small-scale

0.621

High

429172

VPS15
Serine/threonine-protein kinase VPS15

1

4

High-throughput

0.618

High

429175

VPS34
Phosphatidylinositol 3-kinase VPS34

1

10

High-throughput

0.618

High

429191

SEC3
Exocyst complex component SEC3

1

8

Small-scale

0.618

High

429230

ATG1
Serine/threonine-protein kinase ATG1

1

7

High-throughput

0.618

High

429202

RGD1
RHO GTPase-activating protein RGD1

1

0

Small-scale

0.586

High

429165

HSC82
ATP-dependent molecular chaperone HSC82

2

6

High-throughput

0.584

High

429217

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

3

High-throughput

0.584

High

429234

MSO1
Protein MSO1

2

0

Small-scale

0.581

High

429236

YIF1
Protein transport protein YIF1

2

4

Small-scale

0.578

High

429235

PRA1
Prenylated Rab acceptor 1

1

12

Small-scale

0.573

High

429212

SEC9
Protein transport protein SEC9

2

0

Small-scale

0.561

High

429170

RAD53
Serine/threonine-protein kinase RAD53

1

4

High-throughput

0.553

High

429176

SIS1
Protein SIS1

1

3

High-throughput

0.553

High

429239

CDC14
Tyrosine-protein phosphatase CDC14

1

3

Small-scale

0.552

High

429257

LAS17
Proline-rich protein LAS17

1

5

Small-scale

0.543

High

429216

GYP8
GTPase-activating protein GYP8

1

0

Small-scale

0.541

High

429182

HXT1
Low-affinity glucose transporter HXT1

1

1

High-throughput

0.541

High

429238

ALO
D-arabinono-1,4-lactone oxidase

1

1

High-throughput

0.541

High

429229

YIP4
Protein YIP4

1

7

Small-scale

0.523

High

429186

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

0

Small-scale

0.518

High

429258

PEX11
Peroxisomal membrane protein PMP27

1

0

High-throughput

0.518

High

429169

EXO70
Exocyst complex component EXO70

1

1

Small-scale

0.501

High

429187

SEC8
Exocyst complex component SEC8

1

2

Small-scale

0.501

High

429200

EXO84
Exocyst complex component EXO84

1

1

Small-scale

0.501

High

429228

YIP1
Protein transport protein YIP1

1

7

Small-scale

0.481

High

365592

HSP82
ATP-dependent molecular chaperone HSP82

1

6

High-throughput

0.479

High

429164

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

3

Small-scale

0.479

High

429166

SEC23
Protein transport protein SEC23

1

4

High-throughput

0.479

High

429171

TRX1
Thioredoxin-1

1

2

High-throughput

0.479

High

429179

SNC1
Synaptobrevin homolog 1

1

12

Small-scale

0.479

High

429181

SMY1
Kinesin-related protein SMY1

1

6

Small-scale

0.479

High

429192

HSP78
Heat shock protein 78, mitochondrial

1

3

High-throughput

0.479

High

429193

GCN1
eIF-2-alpha kinase activator GCN1

1

4

Small-scale

0.479

High

429194

KES1
Oxysterol-binding protein homolog 4

1

4

Small-scale

0.479

High

429199

ATG8
Autophagy-related protein 8

1

7

High-throughput

0.479

High

429201

ATG14
Autophagy-related protein 14

1

1

High-throughput

0.479

High

429203

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.479

High

429207

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

1

High-throughput

0.479

High

429213

SEC24
Protein transport protein SEC24

1

4

High-throughput

0.479

High

429218

ATG18
Autophagy-related protein 18

1

5

High-throughput

0.479

High

429220

SFT1
Protein transport protein SFT1

1

1

High-throughput

0.479

High

429221

ATG27
Autophagy-related protein 27

1

1

High-throughput

0.479

High

429226

TOM22
Mitochondrial import receptor subunit TOM22

1

1

High-throughput

0.479

High

429232

MLC1
Myosin light chain 1

1

2

Small-scale

0.479

High

429241

BECN1
Vacuolar protein sorting-associated protein 30

1

1

High-throughput

0.479

High

429245

SEC13
Protein transport protein SEC13

1

5

High-throughput

0.479

High

429253

ATG9
Autophagy-related protein 9

1

1

High-throughput

0.479

High

429205

YM11
Uncharacterized protein YMR124W

1

0

Small-scale

0.460

High

429214

BUD6
Bud site selection protein 6

1

0

Small-scale

0.460

High

429243

VPS16
Vacuolar protein sorting-associated protein 16

1

0

Small-scale

0.460

High

357161

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.458

High

429177

SPT5
Transcription elongation factor SPT5

1

0

Small-scale

0.458

High

429196

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

1

0

High-throughput

0.458

High

429215

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

429227

SC6B1
Protein transport protein SBH1

1

0

Small-scale

0.458

High

429256

YOP1
Protein YOP1

1

0

Small-scale

0.458

High

429163

HSP71
Heat shock protein SSA1

1

7

High-throughput

0.445

High

429211

SSB2
Ribosome-associated molecular chaperone SSB2

1

8

High-throughput

0.445

High

429240

SED5
Integral membrane protein SED5

1

14

Small-scale

0.445

High

429249

TLG2
t-SNARE affecting a late Golgi compartment protein 2

1

12

Small-scale

0.445

High

429178

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

429180

HS104
Heat shock protein 104

1

4

High-throughput

0.437

High

429183

SPT16
FACT complex subunit SPT16

1

1

High-throughput

0.437

High

429189

SMY2
Protein SMY2

1

1

High-throughput

0.437

High

429198

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

429206

LAA1
AP-1 accessory protein LAA1

1

4

High-throughput

0.437

High

429237

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

2

High-throughput

0.437

High

429242

TOM1
E3 ubiquitin-protein ligase TOM1

1

2

High-throughput

0.437

High

429246

IVY1
Protein IVY1

1

1

Small-scale

0.437

High

429247

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

429248

ATG23
Autophagy-related protein 23

1

1

High-throughput

0.437

High

429259

CMR1
DNA damage-binding protein CMR1

1

5

High-throughput

0.437

High

429195

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

0

High-throughput

0.426

High

429231

YIP5
Protein YIP5

1

1

Small-scale

0.417

High

429219

IRC6
Increased recombination centers protein 6

1

0

Small-scale

0.292

High

429174

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.249

Low

429190

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.249

Low

429204

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.249

Low

429210

PXP1
2-hydroxyacyl-CoA lyase

1

0

High-throughput

0.249

Low

429222

NET1
Nucleolar protein NET1

1

0

Small-scale

0.249

Low

429223

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.249

Low

429224

BPL1
Biotin--protein ligase

1

0

Small-scale

0.249

Low

429252

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.249

Low

429255

HSP42
Heat shock protein 42

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024