Protein: HGH1
Protein HGH1 (HMG1/2 protein homolog)

Gene: HGH1
Organism: Saccharomyces cerevisiae S288C
Interactions: 68
UniProt ID: P48362

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0061770 - translation elongation factor binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

871517

HGH1
Protein HGH1

2

0

Small-scale

0.736

High

751271

CNS1
Hsp70/Hsp90 co-chaperone CNS1

6

2

Small-scale

0.735

High

524472

HSP71
Heat shock protein SSA1

2

1

Small-scale

0.584

High

810724

TCPB
T-complex protein 1 subunit beta

2

3

Small-scale

0.584

High

844408

TCPH
T-complex protein 1 subunit eta

2

1

Small-scale

0.584

High

864992

TCPQ
T-complex protein 1 subunit theta

2

1

Small-scale

0.584

High

670898

SIS1
Protein SIS1

2

1

High-throughput

0.571

High

850086

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

0

High-throughput

0.559

High

676140

MAS5
Mitochondrial protein import protein MAS5

2

0

Small-scale

0.547

High

554022

TCPA
T-complex protein 1 subunit alpha

2

2

Small-scale

0.533

High

810847

TCPG
T-complex protein 1 subunit gamma

2

1

Small-scale

0.533

High

810981

TCPD
T-complex protein 1 subunit delta

2

3

Small-scale

0.533

High

823619

TCPE
T-complex protein 1 subunit epsilon

2

3

Small-scale

0.533

High

843172

PFS2
Polyadenylation factor subunit 2

1

0

High-throughput

0.513

High

660335

STE11
Serine/threonine-protein kinase STE11

1

0

High-throughput

0.480

High

758313

HSL1
Probable serine/threonine-protein kinase HSL1

1

0

High-throughput

0.480

High

381162

H2B1
Histone H2B.1

1

1

Small-scale

0.479

High

381562

H2B2
Histone H2B.2

1

1

Small-scale

0.479

High

579702

HSC82
ATP-dependent molecular chaperone HSC82

1

2

High-throughput

0.479

High

707569

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

708762

TF3B
Transcription factor IIIB 70 kDa subunit

1

1

High-throughput

0.479

High

746521

HFA1
Acetyl-CoA carboxylase, mitochondrial

1

1

Small-scale

0.479

High

871523

RUVB1
RuvB-like protein 1

1

1

Small-scale

0.479

High

871530

RUVB2
RuvB-like protein 2

1

1

Small-scale

0.479

High

826032

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.460

High

367497

TRPE
Anthranilate synthase component 1

1

0

Small-scale

0.458

High

449146

CALM
Calmodulin

1

0

Small-scale

0.458

High

558799

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.458

High

586473

PCNA
Proliferating cell nuclear antigen

1

0

Small-scale

0.458

High

666498

DBP2
ATP-dependent RNA helicase DBP2

1

0

Small-scale

0.458

High

727163

HS104
Heat shock protein 104

1

0

High-throughput

0.458

High

736866

APE2
Aminopeptidase 2, mitochondrial

1

0

Small-scale

0.458

High

751640

SERC
Phosphoserine aminotransferase

1

0

Small-scale

0.458

High

776611

DEF1
RNA polymerase II degradation factor 1

1

0

Small-scale

0.458

High

796332

FL2D
Protein MUM2

1

0

Small-scale

0.458

High

825969

GVP36
Protein GVP36

1

0

Small-scale

0.458

High

864020

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

Small-scale

0.458

High

871519

HST2
NAD-dependent protein deacetylase HST2

1

0

High-throughput

0.458

High

871524

RPN9
26S proteasome regulatory subunit RPN9

1

0

Small-scale

0.458

High

871527

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

392999

HSP82
ATP-dependent molecular chaperone HSP82

1

2

High-throughput

0.445

High

527101

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

871525

SP382
Pre-mRNA-splicing factor SPP382

1

0

High-throughput

0.438

High

502659

RS25B
Small ribosomal subunit protein eS25B

1

1

Small-scale

0.437

High

503808

RL27A
Large ribosomal subunit protein eL27A

1

1

Small-scale

0.437

High

503933

RL27B
Large ribosomal subunit protein eL27B

1

1

Small-scale

0.437

High

831846

RS29A
Small ribosomal subunit protein uS14A

1

1

Small-scale

0.437

High

831877

RS29B
Small ribosomal subunit protein uS14B

1

1

Small-scale

0.437

High

871521

ACAC
Acetyl-CoA carboxylase

1

1

Small-scale

0.437

High

871522

HAS1
ATP-dependent RNA helicase HAS1

1

1

Small-scale

0.437

High

871529

DBP10
ATP-dependent RNA helicase DBP10

1

1

High-throughput

0.437

High

871532

RS25A
Small ribosomal subunit protein eS25A

1

1

Small-scale

0.437

High

394703

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

863640

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

871531

SET6
Potential protein lysine methyltransferase SET6

1

0

High-throughput

0.426

High

734147

EF2
Elongation factor 2

5

0

Small-scale

0.372

High

811116

TCPZ
T-complex protein 1 subunit zeta

3

0

Small-scale

0.342

High

511445

RL43B
Large ribosomal subunit protein eL43B

1

0

Small-scale

0.249

Low

511944

RS30A
Small ribosomal subunit protein eS30A

1

0

Small-scale

0.249

Low

554939

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

0

Small-scale

0.249

Low

610174

PDI
Protein disulfide-isomerase

1

0

Small-scale

0.249

Low

797554

MCFS2
Medium-chain fatty acid ethyl ester synthase/esterase 2

1

0

Small-scale

0.249

Low

871518

MLC1
Myosin light chain 1

1

0

Small-scale

0.249

Low

871520

NUM1
Nuclear migration protein NUM1

1

0

High-throughput

0.249

Low

871528

GAS5
1,3-beta-glucanosyltransferase GAS5

1

0

Small-scale

0.249

Low

784217

RM27
Large ribosomal subunit protein mL41

1

0

High-throughput

0.238

Low

871526

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025