Protein: TRPE
Anthranilate synthase component 1 (EC 4.1.3.27) (Anthranilate synthase component I)

Gene: TRPE, TRP2
Organism: Saccharomyces cerevisiae S288C
Interactions: 54
UniProt ID: P00899

Gene Ontology (top 5):
GO:0000162 - L-tryptophan biosynthetic process
GO:0004049 - anthranilate synthase activity
GO:0005737 - cytoplasm
GO:0005950 - anthranilate synthase complex
GO:0006541 - glutamine metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

367458

TRPG
Multifunctional tryptophan biosynthesis protein [Includes: Anthranilate synthase component 2

6

5

Small-scale

0.948

High

367471

METK1
S-adenosylmethionine synthase 1

2

0

High-throughput

0.595

High

367488

RPN1
26S proteasome regulatory subunit RPN1

2

0

High-throughput

0.585

High

367494

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

0

High-throughput

0.559

High

367463

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.546

High

367495

BNA3
Probable kynurenine--oxoglutarate transaminase BNA3

1

0

High-throughput

0.518

High

367464

IF4E
Eukaryotic translation initiation factor 4E

1

0

High-throughput

0.513

High

367510

STB3
Protein STB3

1

0

High-throughput

0.493

High

367496

DOHH
Deoxyhypusine hydroxylase

1

0

High-throughput

0.486

High

367502

STE20
Serine/threonine-protein kinase STE20

1

0

High-throughput

0.480

High

367459

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.479

High

367461

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

367474

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.479

High

367479

HS104
Heat shock protein 104

1

3

High-throughput

0.479

High

367475

MYO2
Myosin-2

1

0

Small-scale

0.460

High

367507

RIO1
Serine/threonine-protein kinase RIO1

1

0

Small-scale

0.460

High

367466

PBS2
MAP kinase kinase PBS2

1

0

High-throughput

0.458

High

367468

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

367473

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.458

High

367481

HOG1
Mitogen-activated protein kinase HOG1

1

0

High-throughput

0.458

High

367482

TCA17
TRAPP-associated protein TCA17

1

0

Small-scale

0.458

High

367483

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.458

High

367485

GBLP
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.458

High

367497

HGH1
Protein HGH1

1

0

Small-scale

0.458

High

367499

HST2
NAD-dependent protein deacetylase HST2

1

0

High-throughput

0.458

High

367501

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

367506

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

367508

SIZ2
E3 SUMO-protein ligase SIZ2

1

0

High-throughput

0.458

High

367511

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.458

High

367460

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.445

High

367469

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.445

High

367470

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.445

High

367472

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.445

High

367484

HSP78
Heat shock protein 78, mitochondrial

1

3

High-throughput

0.445

High

367491

SSB2
Ribosome-associated molecular chaperone SSB2

1

3

High-throughput

0.445

High

367478

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

367493

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.426

High

367480

EF2
Elongation factor 2

1

1

High-throughput

0.407

High

367492

COPB2
Coatomer subunit beta'

2

0

High-throughput

0.319

High

367486

ARPC1
Actin-related protein 2/3 complex subunit 1

1

0

High-throughput

0.282

High

367462

SIR3
Regulatory protein SIR3

1

0

High-throughput

0.249

Low

367465

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

367467

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

0

Small-scale

0.249

Low

367476

SIS1
Protein SIS1

1

0

High-throughput

0.249

Low

367477

SPB4
ATP-dependent rRNA helicase SPB4

1

0

High-throughput

0.249

Low

367487

MIP6
RNA-binding protein MIP6

1

0

High-throughput

0.249

Low

367489

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.249

Low

367490

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

367498

NMA2
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2

1

0

High-throughput

0.249

Low

367500

H3
Histone H3

1

0

High-throughput

0.249

Low

367503

CSN9
COP9 signalosome complex subunit 9

1

0

Small-scale

0.249

Low

367504

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

367505

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

367509

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025