Protein: CAF40
Protein CAF40 (40 kDa CCR4-associated factor)

Gene: CAF40
Organism: Saccharomyces cerevisiae S288C
Interactions: 80
UniProt ID: P53829

Gene Ontology (top 5):
GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0000932 - P-body
GO:0005634 - nucleus
GO:0017148 - negative regulation of translation
GO:0030015 - CCR4-NOT core complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

636165

NOT1
General negative regulator of transcription subunit 1

14

3

Small-scale

0.982

High

865173

CAF40
Protein CAF40

2

2

Small-scale

0.793

High

759095

POP2
Poly(A) ribonuclease POP2

12

5

Small-scale

0.760

High

680052

CCR4
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4

11

5

Small-scale

0.759

High

713710

NOT4
General negative regulator of transcription subunit 4

14

2

Small-scale

0.758

High

409856

NOT2
General negative regulator of transcription subunit 2

9

7

Small-scale

0.751

High

865187

NOT5
General negative regulator of transcription subunit 5

9

4

Small-scale

0.751

High

410018

NOT3
General negative regulator of transcription subunit 3

7

4

Small-scale

0.747

High

861143

CF130
Protein CAF130

8

0

Small-scale

0.717

High

512228

SSB1
Ribosome-associated molecular chaperone SSB1

2

1

High-throughput

0.601

High

728294

DEF1
RNA polymerase II degradation factor 1

2

0

High-throughput

0.588

High

634483

MET14
Karyogamy protein KAR4

2

0

High-throughput

0.587

High

710425

PIN4
RNA-binding protein PIN4

2

0

High-throughput

0.587

High

865181

WHI4
Protein WHI4

2

1

High-throughput

0.555

High

662935

TF2B
Transcription initiation factor IIB

2

0

High-throughput

0.551

High

629437

PUF4
Pumilio homology domain family member 4

1

5

High-throughput

0.541

High

759500

MPT5
Suppressor protein MPT5

1

5

High-throughput

0.541

High

761999

DHH1
ATP-dependent RNA helicase DHH1

1

1

High-throughput

0.541

High

865186

PUF2
mRNA-binding protein PUF2

1

5

High-throughput

0.541

High

676253

XPO1
Exportin-1

1

2

High-throughput

0.536

High

693560

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

High-throughput

0.518

High

767806

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

0

High-throughput

0.518

High

862696

DCP2
m7GpppN-mRNA hydrolase

1

0

High-throughput

0.518

High

605568

DBF2
Cell cycle protein kinase DBF2

1

1

Small-scale

0.508

High

745014

PBP2
PAB1-binding protein 2

1

1

High-throughput

0.508

High

865177

NACB1
Nascent polypeptide-associated complex subunit beta-1

1

1

Small-scale

0.508

High

865180

CDD
Cytidine deaminase

1

1

High-throughput

0.508

High

686976

GLNA
Glutamine synthetase

1

0

High-throughput

0.493

High

630427

RNQ1
[PIN+] prion protein RNQ1

1

0

High-throughput

0.486

High

865179

ATG17
Autophagy-related protein 17

1

0

High-throughput

0.486

High

865184

RPIA
Ribose-5-phosphate isomerase

1

0

High-throughput

0.486

High

539394

KSS1
Mitogen-activated protein kinase KSS1

1

0

High-throughput

0.480

High

694166

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

1

High-throughput

0.479

High

698893

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

1

High-throughput

0.479

High

753428

ECM29
Proteasome component ECM29

1

1

High-throughput

0.479

High

771521

NACB2
Nascent polypeptide-associated complex subunit beta-2

1

1

Small-scale

0.479

High

810889

MTR4
ATP-dependent RNA helicase DOB1

1

1

Small-scale

0.479

High

578554

SEC18
Vesicular-fusion protein SEC18

1

2

High-throughput

0.464

High

597337

PSA1
Proteasome subunit alpha type-1

1

0

High-throughput

0.458

High

689197

PSA5
Proteasome subunit alpha type-5

1

0

High-throughput

0.458

High

703702

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.458

High

748955

HSM3
DNA mismatch repair protein HSM3

1

0

High-throughput

0.458

High

751174

PSB1
Proteasome subunit beta type-1

1

0

High-throughput

0.458

High

797322

BLM10
Proteasome activator BLM10

1

0

High-throughput

0.458

High

863686

PAP2
Poly(A) RNA polymerase protein 2

1

0

Small-scale

0.458

High

865178

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

865185

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

713294

WHI3
Protein WHI3

1

1

High-throughput

0.457

High

492017

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

494608

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

696032

HSP79
Heat shock protein homolog SSE2

1

2

High-throughput

0.445

High

753900

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.445

High

769083

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

860188

THG1
tRNA(His) guanylyltransferase

1

0

High-throughput

0.438

High

498562

METK1
S-adenosylmethionine synthase 1

1

1

Small-scale

0.437

High

583243

METK2
S-adenosylmethionine synthase 2

1

1

Small-scale

0.437

High

773965

MLP2
Protein MLP2

1

1

Small-scale

0.437

High

865175

MLP1
Protein MLP1

1

1

Small-scale

0.437

High

454419

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.426

High

628323

SIS1
Protein SIS1

1

0

High-throughput

0.426

High

756700

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

Small-scale

0.426

High

761277

CAJ1
Protein CAJ1

1

0

High-throughput

0.426

High

865174

NST1
Stress response protein NST1

3

0

High-throughput

0.344

High

758008

SSN2
Mediator of RNA polymerase II transcription subunit 13

2

0

Small-scale

0.313

High

689813

RIM1
Single-stranded DNA-binding protein RIM1, mitochondrial

1

0

High-throughput

0.282

High

753502

PHS
Putative pterin-4-alpha-carbinolamine dehydratase

1

0

High-throughput

0.265

Low

865183

HUA2
Protein HUA2

1

0

High-throughput

0.265

Low

701015

SMY2
Protein SMY2

1

0

High-throughput

0.249

Low

706160

MFT1
THO complex subunit MFT1

1

0

Small-scale

0.249

Low

797706

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

1

0

High-throughput

0.249

Low

811599

YJY1
Uncharacterized protein YJR011C

1

0

High-throughput

0.249

Low

865176

NU100
Nucleoporin NUP100/NSP100

1

0

Small-scale

0.249

Low

865182

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.249

Low

360981

TBB
Tubulin beta chain

1

0

High-throughput

0.232

Low

424642

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.232

Low

544182

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.232

Low

556207

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.232

Low

707899

GCN1
eIF-2-alpha kinase activator GCN1

1

0

High-throughput

0.232

Low

785140

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024