Protein: EFC4B
EF-hand calcium-binding domain-containing protein 4B (Calcium release-activated calcium channel regulator 2A) (CRAC channel regulator 2A) (Calcium release-activated channel regulator 2A) (Ras-related protein Rab-46) (EC 3.6.5.2)

Gene: EFC4B, CRACR2A
Organism: Homo sapiens
Interactions: 67
UniProt ID: Q9BSW2

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0001772 - immunological synapse
GO:0002115 - store-operated calcium entry
GO:0002250 - adaptive immune response
GO:0003924 - GTPase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

276720

FKBP6
Inactive peptidyl-prolyl cis-trans isomerase FKBP6

2

2

High-throughput

0.783

High

1412934

TRIM1
Probable E3 ubiquitin-protein ligase MID2

2

14

High-throughput

0.783

High

976522

RB11A
Ras-related protein Rab-11A

2

20

High-throughput

0.754

High

1329225

ANR29
Ankyrin repeat domain-containing protein 29

2

5

High-throughput

0.700

High

1412936

ASB3
Ankyrin repeat and SOCS box protein 3

2

4

High-throughput

0.700

High

302081

SEGN
Secretagogin

1

1

High-throughput

0.691

High

1129118

PLSI
Plastin-1

1

4

High-throughput

0.691

High

1249837

BTNL9
Butyrophilin-like protein 9

1

5

High-throughput

0.691

High

1412933

PD1L1
Programmed cell death 1 ligand 1

1

18

High-throughput

0.691

High

1061852

TLE5
TLE family member 5

4

1

High-throughput

0.637

High

1337542

MCPH1
Microcephalin

3

0

High-throughput

0.634

High

1383236

CLUA1
Clusterin-associated protein 1

3

0

High-throughput

0.629

High

1412935

CDC23
Cell division cycle protein 23 homolog

1

0

High-throughput

0.619

High

630618

RAB3B
Ras-related protein Rab-3B

1

18

High-throughput

0.618

High

945083

RAB25
Ras-related protein Rab-25

1

20

High-throughput

0.618

High

250325

VINEX
Vinexin

2

7

High-throughput

0.606

High

288495

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

2

4

High-throughput

0.606

High

1063576

GOGA2
Golgin subfamily A member 2

2

8

High-throughput

0.606

High

1093939

TRAF1
TNF receptor-associated factor 1

2

2

High-throughput

0.606

High

1315623

IZUM1
Izumo sperm-egg fusion protein 1

2

0

High-throughput

0.602

High

1219827

ARMC3
Armadillo repeat-containing protein 3

1

6

High-throughput

0.595

High

180373

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

2

0

High-throughput

0.580

High

775467

DDIT3
DNA damage-inducible transcript 3 protein

2

0

High-throughput

0.580

High

1330220

ZN655
Zinc finger protein 655

2

0

High-throughput

0.580

High

1336394

SLAI1
SLAIN motif-containing protein 1

2

0

High-throughput

0.580

High

1336558

FA156
Protein FAM156A/FAM156B

2

0

High-throughput

0.580

High

1407067

MDFI
MyoD family inhibitor

2

0

High-throughput

0.580

High

1277374

NT2NA
Notch homolog 2 N-terminal-like protein A

1

4

High-throughput

0.573

High

1387004

ORAI1
Calcium release-activated calcium channel protein 1

1

2

Small-scale

0.569

High

281406

GGYF1
GRB10-interacting GYF protein 1

2

5

High-throughput

0.553

High

1146128

K1H1
Keratin, type I cuticular Ha1

2

1

High-throughput

0.553

High

1350710

CCHCR
Coiled-coil alpha-helical rod protein 1

2

7

High-throughput

0.553

High

1400217

PNMA5
Paraneoplastic antigen-like protein 5

2

2

High-throughput

0.553

High

1227366

A16L1
Autophagy-related protein 16-1

1

7

High-throughput

0.553

High

1111680

STIM1
Stromal interaction molecule 1

1

4

Small-scale

0.550

High

928335

ATN1
Atrophin-1

1

1

High-throughput

0.541

High

166028

FFAR1
Free fatty acid receptor 1

1

7

High-throughput

0.536

High

1399599

OPALI
Opalin

1

2

High-throughput

0.536

High

1412930

DUS15
Dual specificity protein phosphatase 15

1

3

High-throughput

0.536

High

1412937

GPR45
Probable G-protein coupled receptor 45

1

7

High-throughput

0.536

High

843928

HD
Huntingtin

1

10

High-throughput

0.515

High

1279725

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

3

High-throughput

0.515

High

226361

SNG1
Synaptogyrin-1

1

0

High-throughput

0.513

High

1251744

CERS6
Ceramide synthase 6

1

0

High-throughput

0.513

High

1281392

LHPL4
LHFPL tetraspan subfamily member 4 protein

1

0

High-throughput

0.513

High

1120958

TRI29
Tripartite motif-containing protein 29

1

3

High-throughput

0.494

High

1112691

CUL1
Cullin-1

1

7

Small-scale

0.479

High

1233454

LTOR1
Ragulator complex protein LAMTOR1

1

5

High-throughput

0.479

High

1402883

ORAI2
Protein orai-2

1

2

Small-scale

0.479

High

1411591

ORAI3
Protein orai-3

1

2

Small-scale

0.479

High

109502

G5E9A7
DM1 locus, WD repeat containing

1

4

High-throughput

0.470

High

167383

KLF11
Krueppel-like factor 11

1

3

High-throughput

0.470

High

1367928

RORB
Nuclear receptor ROR-beta

1

6

High-throughput

0.470

High

867822

IF1AX
Eukaryotic translation initiation factor 1A, X-chromosomal

1

0

High-throughput

0.458

High

947268

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.458

High

1201928

Q58EY0
RAR related orphan receptor B isoform 1

1

6

High-throughput

0.439

High

217187

MS18B
Protein Mis18-beta

2

0

High-throughput

0.316

High

341843

K2C75
Keratin, type II cytoskeletal 75

2

0

High-throughput

0.316

High

600116

ZNF20
Zinc finger protein 20

2

0

High-throughput

0.316

High

1186908

KR195
Keratin-associated protein 19-5

2

0

High-throughput

0.316

High

1198846

ZC21C
Zinc finger C2HC domain-containing protein 1C

2

0

High-throughput

0.316

High

1212449

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

2

0

High-throughput

0.316

High

1412931

F86C1
Putative protein FAM86C1P

2

0

High-throughput

0.316

High

1412932

RBAK
RB-associated KRAB zinc finger protein

2

0

High-throughput

0.316

High

1093702

MKRN3
E3 ubiquitin-protein ligase makorin-3

1

0

High-throughput

0.299

High

1126354

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

0

High-throughput

0.279

Low

1307027

KR131
Keratin-associated protein 13-1

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025