Protein: SHPS1
Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (MyD-1 antigen) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (mSIRP-alpha1) (p84) (CD antigen CD172a)

Gene: SHPS1, Sirpa
Organism: Mus musculus
Interactions: 23
UniProt ID: P97797

Gene Ontology (top 5):
GO:0001933 - negative regulation of protein phosphorylation
GO:0002244 - hematopoietic progenitor cell differentiation
GO:0005886 - plasma membrane
GO:0006910 - phagocytosis, recognition
GO:0006911 - phagocytosis, engulfment

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

956930

CD47
Leukocyte surface antigen CD47

2

3

Small-scale

0.806

High

956929

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

2

10

High-throughput

0.789

High

719295

PTN11
Tyrosine-protein phosphatase non-receptor type 11

7

13

Small-scale

0.738

High

562613

GHR
Growth hormone receptor

1

12

Small-scale

0.647

High

665983

PTN6
Tyrosine-protein phosphatase non-receptor type 6

3

13

Small-scale

0.640

High

192945

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

6

High-throughput

0.618

High

677248

SSR3
Somatostatin receptor type 3

1

11

High-throughput

0.618

High

956925

SHPS1
Tyrosine-protein phosphatase non-receptor type substrate 1

1

16

Small-scale

0.575

High

956931

JAK2
Tyrosine-protein kinase JAK2

1

17

Small-scale

0.561

High

956937

HOME1
Homer protein homolog 1

1

3

High-throughput

0.536

High

193094

FYB1
FYN-binding protein 1

1

8

Small-scale

0.479

High

643077

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

18

Small-scale

0.479

High

956926

SHC1
SHC-transforming protein 1

1

20

Small-scale

0.479

High

956927

STING
Stimulator of interferon genes protein

1

1

High-throughput

0.479

High

956928

SKAP1
Src kinase-associated phosphoprotein 1

1

4

Small-scale

0.479

High

956935

FAK2
Protein-tyrosine kinase 2-beta

1

17

Small-scale

0.479

High

421453

CSF1
Macrophage colony-stimulating factor 1

1

2

Small-scale

0.445

High

102987

G3X9H5
Huntingtin

1

1

High-throughput

0.437

High

956932

NR0B2
Nuclear receptor subfamily 0 group B member 2

1

5

Small-scale

0.437

High

956933

FBX2
F-box only protein 2

1

10

Small-scale

0.437

High

956936

SKP1
S-phase kinase-associated protein 1

1

0

Small-scale

0.249

Low

956934

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024