Protein: TRXB1
Thioredoxin reductase 1 (TR) (TrxR) (EC 1.8.1.9) (Thioredoxin peroxidase 1) (TPx) (Thioredoxin-dependent peroxide reductase 1)

Gene: TRXB1, TRR1
Organism: Saccharomyces cerevisiae S288C
Interactions: 45
UniProt ID: P29509

Gene Ontology (top 5):
GO:0004791 - thioredoxin-disulfide reductase (NADPH) activity
GO:0005739 - mitochondrion
GO:0005758 - mitochondrial intermembrane space
GO:0005829 - cytosol
GO:0008198 - ferrous iron binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

713498

TRXB2
Thioredoxin reductase 2, mitochondrial

7

18

Small-scale

0.955

High

652856

TRX2
Thioredoxin-2

3

14

Small-scale

0.835

High

713491

TRXB1
Thioredoxin reductase 1

2

17

Small-scale

0.726

High

713508

RHO5
GTP-binding protein RHO5

2

3

Small-scale

0.653

High

673326

TRX3
Thioredoxin-3, mitochondrial

1

17

Small-scale

0.647

High

646589

TRX1
Thioredoxin-1

1

14

Small-scale

0.575

High

544078

SSB1
Ribosome-associated molecular chaperone SSB1

2

3

High-throughput

0.571

High

670424

SIS1
Protein SIS1

2

2

High-throughput

0.571

High

624976

PRP6
Pre-mRNA-splicing factor 6

1

1

High-throughput

0.489

High

713495

FIMB
Fimbrin

1

5

High-throughput

0.489

High

713505

TEL2
Telomere length regulation protein TEL2

1

0

High-throughput

0.486

High

626476

AP1
AP-1-like transcription factor YAP1

1

0

Small-scale

0.480

High

578989

HSC82
ATP-dependent molecular chaperone HSC82

1

3

High-throughput

0.479

High

713499

RPN10
26S proteasome regulatory subunit RPN10

1

1

High-throughput

0.479

High

713502

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

3

High-throughput

0.479

High

713509

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.479

High

416394

HXKA
Hexokinase-1

1

0

High-throughput

0.458

High

646327

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.458

High

713500

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

713506

MTM1
Mitochondrial carrier protein MTM1

1

0

High-throughput

0.458

High

713510

RAGAB
GTP-binding protein GTR1

1

0

Small-scale

0.458

High

713513

ESP1
Separin

1

0

High-throughput

0.458

High

713521

PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

1

0

High-throughput

0.458

High

523282

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.445

High

526114

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.445

High

713494

HSP79
Heat shock protein homolog SSE2

1

11

High-throughput

0.445

High

713501

SSB2
Ribosome-associated molecular chaperone SSB2

1

3

High-throughput

0.445

High

713511

CTF4
DNA polymerase alpha-binding protein

1

3

High-throughput

0.437

High

713514

TOM1
E3 ubiquitin-protein ligase TOM1

1

1

High-throughput

0.437

High

713516

AP3D
AP-3 complex subunit delta

1

1

High-throughput

0.437

High

713520

DBP10
ATP-dependent RNA helicase DBP10

1

1

High-throughput

0.437

High

713497

LHS1
Heat shock protein 70 homolog LHS1

1

6

High-throughput

0.407

High

713496

SUI1
Eukaryotic translation initiation factor eIF-1

1

0

High-throughput

0.279

Low

713507

PPID
Peptidyl-prolyl cis-trans isomerase CPR6

1

0

High-throughput

0.279

Low

713518

YGK3
Glycogen synthase kinase-3 homolog YGK3

1

0

High-throughput

0.279

Low

713504

SCS3
Acyl-coenzyme A diphosphatase SCS3

1

0

Small-scale

0.251

Low

713512

ULP1
Ubiquitin-like-specific protease 1

1

0

High-throughput

0.251

Low

706414

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

713492

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.249

Low

713493

MET4
Transcriptional activator of sulfur metabolism MET4

1

0

High-throughput

0.249

Low

713503

UBC9
SUMO-conjugating enzyme UBC9

1

0

High-throughput

0.249

Low

713515

YMC0
Uncharacterized protein YML020W

1

0

High-throughput

0.249

Low

713517

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.249

Low

713519

NAA25
N-terminal acetyltransferase B complex subunit MDM20

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025