Protein: FIMB
Fimbrin (ABP67)

Gene: FIMB, SAC6
Organism: Saccharomyces cerevisiae S288C
Interactions: 93
UniProt ID: P32599

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005884 - actin filament
GO:0005886 - plasma membrane
GO:0005934 - cellular bud tip
GO:0007015 - actin filament organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

743353

ACT
Actin

11

20

Small-scale

0.981

High

449097

CALM
Calmodulin

1

1

Small-scale

0.618

High

647731

RFA1
Replication factor A protein 1

2

9

Small-scale

0.606

High

518242

IF4A
ATP-dependent RNA helicase eIF4A

2

1

High-throughput

0.601

High

743345

BNI1
Protein BNI1

2

2

Small-scale

0.594

High

743343

ARPC5
Actin-related protein 2/3 complex subunit 5

2

0

High-throughput

0.587

High

579067

HSC82
ATP-dependent molecular chaperone HSC82

2

7

High-throughput

0.584

High

743332

ATG8
Autophagy-related protein 8

2

9

High-throughput

0.584

High

743346

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

5

High-throughput

0.584

High

743368

LAS17
Proline-rich protein LAS17

2

3

Small-scale

0.584

High

743341

SSB2
Ribosome-associated molecular chaperone SSB2

2

4

High-throughput

0.552

High

562949

CAPZB
F-actin-capping protein subunit beta

1

2

High-throughput

0.541

High

605293

CAP
Adenylyl cyclase-associated protein

1

2

High-throughput

0.541

High

743333

ARPC1
Actin-related protein 2/3 complex subunit 1

1

6

High-throughput

0.541

High

604929

MDHM
Malate dehydrogenase, mitochondrial

1

3

High-throughput

0.536

High

628049

FKBP
FK506-binding protein 1

1

4

High-throughput

0.536

High

554678

YPK1
Serine/threonine-protein kinase YPK1

1

3

High-throughput

0.515

High

671942

HAL4
Serine/threonine-protein kinase HAL4/SAT4

1

10

High-throughput

0.515

High

743319

RAD23
UV excision repair protein RAD23

1

7

High-throughput

0.515

High

743363

CHS5
Chitin biosynthesis protein CHS5

1

2

High-throughput

0.515

High

743348

LCF4
Long-chain-fatty-acid--CoA ligase 4

1

0

High-throughput

0.513

High

364423

CDK1
Cyclin-dependent kinase 1

1

4

Small-scale

0.501

High

359447

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

2

High-throughput

0.500

High

366784

IPYR
Inorganic pyrophosphatase

1

2

High-throughput

0.500

High

367723

ENO1
Enolase 1

1

2

High-throughput

0.500

High

743324

BMH2
Protein BMH2

1

3

High-throughput

0.500

High

624989

PRP6
Pre-mRNA-splicing factor 6

1

2

High-throughput

0.489

High

713495

TRXB1
Thioredoxin reductase 1

1

5

High-throughput

0.489

High

743338

RV167
Reduced viability upon starvation protein 167

1

8

Small-scale

0.481

High

572544

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.479

High

365589

PGK
Phosphoglycerate kinase

1

2

Small-scale

0.479

High

392441

HSP82
ATP-dependent molecular chaperone HSP82

1

7

High-throughput

0.479

High

394377

EF1A
Elongation factor 1-alpha

1

2

Small-scale

0.479

High

430813

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

3

Small-scale

0.479

High

434944

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

679504

CDC48
Cell division control protein 48

1

8

High-throughput

0.479

High

726866

HS104
Heat shock protein 104

1

1

High-throughput

0.479

High

743327

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.479

High

743328

YKT6
Synaptobrevin homolog YKT6

1

1

High-throughput

0.479

High

743342

MOB1
DBF2 kinase activator protein MOB1

1

4

High-throughput

0.479

High

743347

ATG18
Autophagy-related protein 18

1

4

High-throughput

0.479

High

743349

RL38
Large ribosomal subunit protein eL38

1

1

Small-scale

0.479

High

743351

ATG1
Serine/threonine-protein kinase ATG1

1

8

High-throughput

0.479

High

743354

NUM1
Nuclear migration protein NUM1

1

20

High-throughput

0.479

High

743356

TOM1
E3 ubiquitin-protein ligase TOM1

1

6

High-throughput

0.479

High

743357

GLRX3
Monothiol glutaredoxin-3

1

8

Small-scale

0.479

High

743364

SGT2
Small glutamine-rich tetratricopeptide repeat-containing protein 2

1

10

Small-scale

0.479

High

448372

RAD1
DNA repair protein RAD1

1

1

High-throughput

0.470

High

743350

NU145
Nucleoporin NUP145

1

4

High-throughput

0.470

High

743360

HRD1
ERAD-associated E3 ubiquitin-protein ligase HRD1

1

3

High-throughput

0.470

High

743344

BUD6
Bud site selection protein 6

1

0

Small-scale

0.460

High

512043

RS4A
Small ribosomal subunit protein eS4A

1

0

Small-scale

0.458

High

558648

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.458

High

674501

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

743320

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

743321

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.458

High

743334

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.458

High

743340

YEY6
MYG1 protein YER156C

1

0

Small-scale

0.458

High

743355

ESP1
Separin

1

0

High-throughput

0.458

High

743358

PPN1
Endopolyphosphatase

1

0

Small-scale

0.458

High

743367

HSP42
Heat shock protein 42

1

0

Small-scale

0.458

High

523403

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.445

High

544220

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

741214

HSP7F
Heat shock protein homolog SSE1

1

5

High-throughput

0.445

High

743322

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.445

High

682215

SPB4
ATP-dependent rRNA helicase SPB4

1

2

High-throughput

0.437

High

743330

ANM1
Protein arginine N-methyltransferase 1

1

5

High-throughput

0.437

High

743331

GLU2A
Glucosidase 2 subunit alpha

1

1

Small-scale

0.437

High

743361

ESA1
Histone acetyltransferase ESA1

1

1

Small-scale

0.437

High

743365

ATG9
Autophagy-related protein 9

1

1

High-throughput

0.437

High

743336

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.426

High

419662

H2A2
Histone H2A.2

1

2

High-throughput

0.407

High

670493

SIS1
Protein SIS1

2

0

High-throughput

0.298

High

557683

SRS2
ATP-dependent DNA helicase SRS2

1

0

High-throughput

0.269

Low

734540

MSS51
Protein MSS51, mitochondrial

1

0

High-throughput

0.269

Low

743323

PMT1
Dolichyl-phosphate-mannose--protein mannosyltransferase 1

1

0

High-throughput

0.269

Low

405063

LEU3
3-isopropylmalate dehydrogenase

1

0

High-throughput

0.261

Low

743339

FIR1
Factor interacting with REF2

1

0

Small-scale

0.251

Low

454289

CARP
Saccharopepsin

1

0

Small-scale

0.249

Low

454951

RS19A
Small ribosomal subunit protein eS19A

1

0

Small-scale

0.249

Low

503766

RL27A
Large ribosomal subunit protein eL27A

1

0

Small-scale

0.249

Low

647060

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.249

Low

706553

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

743325

SPT10
Protein SPT10

1

0

High-throughput

0.249

Low

743326

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

743335

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.249

Low

743337

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

743352

PESC
Pescadillo homolog

1

0

High-throughput

0.249

Low

743359

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

743362

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

743366

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.249

Low

743329

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

0

High-throughput

0.232

Low

743369

SET6
Potential protein lysine methyltransferase SET6

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025