Protein: NIP7
60S ribosome subunit biogenesis protein NIP7 (Nuclear import protein 7)

Gene: NIP7
Organism: Saccharomyces cerevisiae S288C
Interactions: 132
UniProt ID: Q08962

Gene Ontology (top 5):
GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

778882

NOP2
25S rRNA

7

2

Small-scale

0.963

High

733967

RPF2
Ribosome biogenesis protein RPF2

8

0

Small-scale

0.713

High

860907

PESC
Pescadillo homolog

6

0

Small-scale

0.695

High

994596

NOP8
60S ribosome subunit biogenesis protein NOP8

5

0

Small-scale

0.687

High

638886

SPB4
ATP-dependent rRNA helicase SPB4

4

2

High-throughput

0.686

High

754931

SSF1
Ribosome biogenesis protein SSF1

4

1

Small-scale

0.678

High

997036

MAK21
Ribosome biogenesis protein MAK21

3

3

High-throughput

0.662

High

973479

NOG1
Nucleolar GTP-binding protein 1

4

0

Small-scale

0.657

High

754217

CIC1
Proteasome-interacting protein CIC1

3

1

High-throughput

0.656

High

766724

NUG1
Nuclear GTP-binding protein NUG1

3

1

Small-scale

0.656

High

976883

HAS1
ATP-dependent RNA helicase HAS1

3

2

High-throughput

0.656

High

994464

BRX1
Ribosome biogenesis protein BRX1

3

4

Small-scale

0.656

High

997032

YTM1
Ribosome biogenesis protein YTM1

3

1

Small-scale

0.656

High

630284

RRP43
Exosome complex component RRP43

3

0

Small-scale

0.648

High

776536

RLP7
Ribosome biogenesis protein RLP7

3

1

Small-scale

0.640

High

859528

NSA1
Ribosome biogenesis protein NSA1

3

0

Small-scale

0.628

High

797411

LOC1
60S ribosomal subunit assembly/export protein LOC1

3

0

High-throughput

0.622

High

866867

RCM1
25S rRNA

1

2

High-throughput

0.618

High

997033

NOP53
Ribosome biogenesis protein NOP53

3

0

Small-scale

0.614

High

768064

NSA2
Ribosome biogenesis protein NSA2

2

1

High-throughput

0.614

High

997037

RL7B
Large ribosomal subunit protein uL30B

2

1

High-throughput

0.611

High

756884

RIX1
Pre-rRNA-processing protein RIX1

2

0

High-throughput

0.585

High

865772

NOP13
Nucleolar protein 13

2

0

High-throughput

0.585

High

979467

PUF6
Pumilio homology domain family member 6

2

0

High-throughput

0.585

High

594082

MAK11
Protein MAK11

2

1

Small-scale

0.584

High

715502

RRP1
Ribosomal RNA-processing protein 1

2

1

Small-scale

0.584

High

866282

NOP15
Ribosome biogenesis protein 15

2

1

High-throughput

0.584

High

996377

RRS1
Regulator of ribosome biosynthesis

2

1

High-throughput

0.571

High

764268

NOC2
Nucleolar complex protein 2

2

0

Small-scale

0.559

High

978445

RRP17
Ribosomal RNA-processing protein 17

2

0

High-throughput

0.559

High

992650

SDO1
Ribosome maturation protein SDO1

1

0

Small-scale

0.549

High

755347

RPF1
Ribosome production factor 1

2

0

High-throughput

0.547

High

667294

RL8B
Large ribosomal subunit protein eL8B

1

1

High-throughput

0.536

High

696425

PP12
Serine/threonine-protein phosphatase PP1-2

1

1

High-throughput

0.536

High

513057

SSB1
Ribosome-associated molecular chaperone SSB1

2

0

High-throughput

0.528

High

533954

INO4
Protein INO4

1

0

High-throughput

0.513

High

641093

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.513

High

864628

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.513

High

965062

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.513

High

977782

ARX1
Probable metalloprotease ARX1

1

0

High-throughput

0.513

High

992249

RIX7
Ribosome biogenesis ATPase RIX7

1

0

High-throughput

0.513

High

995903

DIA2
Protein DIA2

1

0

High-throughput

0.513

High

480363

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

634463

SPB1
27S pre-rRNA

1

1

High-throughput

0.479

High

663574

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

663929

TF3B
Transcription factor IIIB 70 kDa subunit

1

1

High-throughput

0.479

High

698970

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

1

High-throughput

0.479

High

699744

DRS1
ATP-dependent RNA helicase DRS1

1

1

High-throughput

0.479

High

703134

MRT4
Ribosome assembly factor MRT4

1

2

High-throughput

0.479

High

705763

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.479

High

733171

DBP7
ATP-dependent RNA helicase DBP7

1

2

Small-scale

0.479

High

742084

NOP4
Nucleolar protein 4

1

1

High-throughput

0.479

High

757368

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

1

High-throughput

0.479

High

864701

NOG2
Nucleolar GTP-binding protein 2

1

1

High-throughput

0.479

High

866533

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.479

High

980174

ERB1
Ribosome biogenesis protein ERB1

1

1

High-throughput

0.479

High

986487

FKBP4
FK506-binding protein 4

1

1

High-throughput

0.479

High

986624

DBP9
ATP-dependent RNA helicase DBP9

1

1

High-throughput

0.479

High

987681

NOC4
Nucleolar complex protein 4

1

3

High-throughput

0.479

High

992545

NOC3
Nucleolar complex-associated protein 3

1

2

High-throughput

0.479

High

994059

NOP12
Nucleolar protein 12

1

1

High-throughput

0.479

High

997034

SSF2
Ribosome biogenesis protein SSF2

1

1

High-throughput

0.479

High

997038

SMT3
Ubiquitin-like protein SMT3

1

0

High-throughput

0.460

High

383392

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

407374

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

413750

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

481082

RL23B
Large ribosomal subunit protein uL14B

1

0

High-throughput

0.458

High

501266

MAK16
Protein MAK16

1

0

High-throughput

0.458

High

544549

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.458

High

604634

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

0

High-throughput

0.458

High

632133

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

688473

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

693173

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

0

High-throughput

0.458

High

710936

URB1
Nucleolar pre-ribosomal-associated protein 1

1

0

Small-scale

0.458

High

731886

EBP2
rRNA-processing protein EBP2

1

0

High-throughput

0.458

High

732259

RRP14
Ribosomal RNA-processing protein 14

1

0

High-throughput

0.458

High

746278

YBC8
UPF0642 protein YBL028C

1

0

High-throughput

0.458

High

752712

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

765092

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

Small-scale

0.458

High

766609

NOP16
Nucleolar protein 16

1

0

High-throughput

0.458

High

774589

BMT5
25S rRNA

1

0

High-throughput

0.458

High

775280

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.458

High

792620

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

797617

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

0

High-throughput

0.458

High

810942

MTR4
ATP-dependent RNA helicase DOB1

1

0

Small-scale

0.458

High

812143

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

841448

UBC9
SUMO-conjugating enzyme UBC9

1

0

High-throughput

0.458

High

978352

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

979066

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.458

High

979116

RRB1
Ribosome assembly protein RRB1

1

0

High-throughput

0.458

High

982908

RRP5
rRNA biogenesis protein RRP5

1

0

High-throughput

0.458

High

986588

JIP5
WD repeat-containing protein JIP5

1

0

High-throughput

0.458

High

987651

RRP15
Ribosomal RNA-processing protein 15

1

0

High-throughput

0.458

High

991327

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

992628

RLP24
Ribosome biogenesis protein RLP24

1

0

High-throughput

0.458

High

995820

SGO1
Shugoshin

1

0

High-throughput

0.458

High

996334

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

997031

MDN1
Midasin

1

0

High-throughput

0.458

High

997035

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

997039

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.458

High

997040

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.458

High

361067

TBB
Tubulin beta chain

1

1

High-throughput

0.445

High

399660

RLA0
Large ribosomal subunit protein uL10

1

2

High-throughput

0.445

High

454490

TBA1
Tubulin alpha-1 chain

1

1

High-throughput

0.445

High

492716

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

495202

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

499104

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.445

High

695720

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

865504

JJJ1
J protein JJJ1

1

1

High-throughput

0.445

High

340306

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.426

High

368478

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

556351

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

629071

SCJ1
DnaJ-related protein SCJ1

1

0

High-throughput

0.426

High

634205

SRO9
RNA-binding protein SRO9

1

0

High-throughput

0.426

High

760704

TCPB
T-complex protein 1 subunit beta

1

0

High-throughput

0.426

High

785259

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.426

High

854693

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.426

High

687502

EF2
Elongation factor 2

1

1

High-throughput

0.407

High

763488

ERP2
Protein ERP2

2

0

High-throughput

0.307

High

983310

RCH1
Solute carrier RCH1

1

0

High-throughput

0.269

Low

687804

MSB2
Signaling mucin MSB2

1

0

High-throughput

0.265

Low

471843

RL27A
Large ribosomal subunit protein eL27A

1

0

High-throughput

0.249

Low

480931

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

520884

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.249

Low

558690

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

0

High-throughput

0.249

Low

586214

PMA2
Plasma membrane ATPase 2

1

0

High-throughput

0.249

Low

706537

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

752340

HXT5
Probable glucose transporter HXT5

1

0

High-throughput

0.249

Low

762636

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

860404

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

540176

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.232

Low

804866

RSSA2
Small ribosomal subunit protein uS2B

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024