Protein: MEX67
mRNA export factor MEX67

Gene: MEX67
Organism: Saccharomyces cerevisiae S288C
Interactions: 128
UniProt ID: Q99257

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0000055 - ribosomal large subunit export from nucleus
GO:0000056 - ribosomal small subunit export from nucleus
GO:0003723 - RNA binding
GO:0003729 - mRNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

758057

MTR2
mRNA transport regulator MTR2

11

0

Small-scale

0.926

High

1084505

YRA1
RNA annealing protein YRA1

10

6

Small-scale

0.753

High

1038013

NU116
Nucleoporin NUP116/NSP116

9

18

Small-scale

0.751

High

915005

NUP84
Nucleoporin NUP84

7

1

Small-scale

0.743

High

1065127

NCBP2
Nuclear cap-binding protein subunit 2

7

3

Small-scale

0.736

High

738951

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

6

2

Small-scale

0.731

High

1044247

ARX1
Probable metalloprotease ARX1

16

0

Small-scale

0.729

High

1037969

NU100
Nucleoporin NUP100/NSP100

6

19

Small-scale

0.725

High

917715

LSG1
Large subunit GTPase 1

8

0

Small-scale

0.714

High

1031085

NOP3
Serine/arginine

5

8

Small-scale

0.714

High

1036943

MLP1
Protein MLP1

5

5

Small-scale

0.702

High

634297

NUP1
Nucleoporin NUP1

4

12

Small-scale

0.699

High

806192

NMD3
60S ribosomal export protein NMD3

6

0

Small-scale

0.690

High

577361

NSP1
Nucleoporin NSP1

4

20

Small-scale

0.686

High

1061415

BUD20
Bud site selection protein 20

4

1

Small-scale

0.686

High

605941

HPR1
THO complex subunit HPR1

4

0

Small-scale

0.681

High

824829

MLP2
Protein MLP2

4

3

Small-scale

0.676

High

858374

SAC3
Nuclear mRNA export protein SAC3

3

2

Small-scale

0.667

High

632837

DBP5
ATP-dependent RNA helicase DBP5

3

4

Small-scale

0.664

High

403719

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

3

2

Small-scale

0.660

High

858332

NUP85
Nucleoporin NUP85

4

0

Small-scale

0.657

High

813662

NUP60
Nucleoporin NUP60

4

0

Small-scale

0.656

High

886214

NU145
Nucleoporin NUP145

3

15

Small-scale

0.646

High

803522

MIP6
RNA-binding protein MIP6

2

3

Small-scale

0.646

High

757565

NCBP1
Nuclear cap-binding protein complex subunit 1

3

3

Small-scale

0.640

High

782567

NU133
Nucleoporin NUP133

3

1

High-throughput

0.640

High

795301

NU170
Nucleoporin NUP170

3

3

Small-scale

0.640

High

825191

NU159
Nucleoporin NUP159

3

11

Small-scale

0.640

High

1036141

PVH1
Tyrosine-protein phosphatase YVH1

2

2

Small-scale

0.624

High

410425

RL25
Large ribosomal subunit protein uL23

3

0

Small-scale

0.622

High

1403995

MEX67
mRNA export factor MEX67

1

10

High-throughput

0.618

High

1250864

SUS1
SAGA complex subunit SUS1

3

0

Small-scale

0.613

High

916440

SEH1
Nucleoporin SEH1

2

5

Small-scale

0.611

High

509785

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

2

2

Small-scale

0.602

High

877997

NUP57
Nucleoporin NUP57

2

14

Small-scale

0.595

High

864208

ALB1
Ribosome biogenesis protein ALB1

2

0

Small-scale

0.585

High

676784

GBP2
Serine/arginine

2

6

Small-scale

0.584

High

756674

NIC96
Nucleoporin NIC96

2

1

High-throughput

0.584

High

807705

HRB1
Serine/arginine

2

4

Small-scale

0.584

High

817828

NU157
Nucleoporin NUP157

2

3

High-throughput

0.584

High

817857

GLE2
mRNA export factor GLE2

2

6

High-throughput

0.584

High

864658

NU192
Nucleoporin NUP192

2

2

High-throughput

0.584

High

919065

PESC
Pescadillo homolog

2

1

High-throughput

0.584

High

1039087

IMA1
Importin subunit alpha

2

12

High-throughput

0.584

High

1039675

NOG1
Nucleolar GTP-binding protein 1

2

1

High-throughput

0.584

High

1053896

IMB1
Importin subunit beta-1

2

6

High-throughput

0.584

High

1084753

GLE1
mRNA export factor GLE1

2

2

High-throughput

0.584

High

1403996

HRP1
Nuclear polyadenylated RNA-binding protein 4

1

3

Small-scale

0.561

High

150198

THP2
THO complex subunit THP2

2

0

Small-scale

0.559

High

515353

RL35A
Large ribosomal subunit protein uL29A

2

0

Small-scale

0.559

High

776548

NU120
Nucleoporin NUP120

2

0

Small-scale

0.559

High

779942

YRA2
RNA annealing protein YRA2

2

0

Small-scale

0.559

High

805766

YHS7
Uncharacterized protein YHR127W

2

0

High-throughput

0.559

High

813438

PO152
Nucleoporin POM152

2

0

High-throughput

0.559

High

823511

NUP82
Nucleoporin NUP82

2

0

High-throughput

0.559

High

912762

NU188
Nucleoporin NUP188

2

0

High-throughput

0.559

High

1084919

POM34
Nucleoporin POM34

2

0

High-throughput

0.559

High

781166

SWD2
COMPASS component SWD2

1

5

Small-scale

0.552

High

820255

SSB2
Ribosome-associated molecular chaperone SSB2

2

6

High-throughput

0.552

High

656693

KC11
Casein kinase I homolog 1

1

3

High-throughput

0.536

High

1084974

SKM1
Serine/threonine-protein kinase SKM1

1

3

High-throughput

0.536

High

733606

P5CR
Pyrroline-5-carboxylate reductase

1

0

High-throughput

0.518

High

908521

ROM2
RHO1 GDP-GTP exchange protein 2

1

0

High-throughput

0.513

High

886190

NUP42
Nucleoporin NUP42

1

11

Small-scale

0.501

High

150040

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.479

High

433927

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.479

High

435476

RS3
Small ribosomal subunit protein uS3

1

1

Small-scale

0.479

High

455348

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.479

High

534078

HSF
Heat shock transcription factor

1

1

Small-scale

0.479

High

580331

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.479

High

666579

DBP2
ATP-dependent RNA helicase DBP2

1

2

Small-scale

0.479

High

677006

SRO9
RNA-binding protein SRO9

1

3

Small-scale

0.479

High

708679

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

738521

NUP2
Nucleoporin NUP2

1

14

High-throughput

0.479

High

739230

PRP19
Pre-mRNA-processing factor 19

1

5

High-throughput

0.479

High

741206

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

6

High-throughput

0.479

High

750179

MRT4
Ribosome assembly factor MRT4

1

2

Small-scale

0.479

High

792341

GBLP
Small ribosomal subunit protein RACK1

1

5

High-throughput

0.479

High

794248

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

2

Small-scale

0.479

High

798371

ENP1
Essential nuclear protein 1

1

1

Small-scale

0.479

High

820416

RIO2
Serine/threonine-protein kinase RIO2

1

1

Small-scale

0.479

High

919574

SDA1
Protein SDA1

1

1

Small-scale

0.479

High

921206

THO2
THO complex subunit 2

1

2

High-throughput

0.479

High

922701

PPID
Peptidyl-prolyl cis-trans isomerase CPR6

1

3

High-throughput

0.479

High

1055546

NOC4
Nucleolar complex protein 4

1

2

High-throughput

0.479

High

1064852

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.479

High

1084436

RRP6
Exosome complex exonuclease RRP6

1

2

Small-scale

0.479

High

402165

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

Small-scale

0.458

High

409808

RL24A
Large ribosomal subunit protein eL24A

1

0

Small-scale

0.458

High

436256

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

442204

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

514917

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

674925

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

689177

RL16A
Large ribosomal subunit protein uL13A

1

0

High-throughput

0.458

High

713600

RIF1
Telomere length regulator protein RIF1

1

0

High-throughput

0.458

High

738571

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.458

High

753276

MFT1
THO complex subunit MFT1

1

0

High-throughput

0.458

High

778616

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

798520

REI1
Cytoplasmic 60S subunit biogenesis factor REI1

1

0

High-throughput

0.458

High

802474

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

813732

ECM1
Shuttling pre-60S factor ECM1

1

0

High-throughput

0.458

High

815296

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

Small-scale

0.458

High

874620

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

1033660

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

1033913

PRS8
26S proteasome regulatory subunit 8 homolog

1

0

Small-scale

0.458

High

1038075

DYL1
Dynein light chain 1, cytoplasmic

1

0

High-throughput

0.458

High

1044104

NUP53
Nucleoporin NUP53

1

0

High-throughput

0.458

High

1059455

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

1064686

TMA16
Translation machinery-associated protein 16

1

0

High-throughput

0.458

High

1084252

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.458

High

1084479

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

525717

HSP71
Heat shock protein SSA1

1

6

High-throughput

0.445

High

893270

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

1

High-throughput

0.445

High

1025209

SEN1
Helicase SEN1

1

4

Small-scale

0.445

High

503330

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

504502

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

512742

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.437

High

652001

ESS1
Peptidyl-prolyl cis-trans isomerase ESS1

1

0

High-throughput

0.426

High

383978

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

511327

RL20B
Large ribosomal subunit protein eL20B

1

0

High-throughput

0.249

Low

513308

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

689750

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

747673

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

748597

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

753679

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

803819

BRL1
Nucleus export protein BRL1

1

0

Small-scale

0.249

Low

812817

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025