HitPredict

Interactor 1: GRAP (Q08012)
Growth factor receptor-bound protein 2 (Downstream of receptor kinase) (Protein enhancer of sevenless 2B)
Gene: drk

Interactor 2: X2JFU3 (X2JFU3)
Uncharacterized protein, isoform E
Gene: anon-15Db

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	22028469
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~SH3_1
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 211 Dm			1 277
+	Hs
		463618 LYN_HUMAN (3-199): 4e-35: 131: 25.24		PHLB2_HUMAN (10-273): 8.05e-66: 224: 32.04
+	Hs
		987954 GRB2_HUMAN (1-210): 1.15e-62: 195: 62.62		PKHA2_HUMAN (150-272): 5.97e-33: 126: 21.95
+	Hs
		987887 GRB2_HUMAN (1-210): 1.15e-62: 195: 62.62		CYH2_HUMAN (136-277): 1.36e-32: 125: 17.47
+	Mm
		1221262 GRB2_MOUSE (1-210): 5.92e-63: 196: 63.08		GAB1_MOUSE (172-275): 1.62e-30: 121: 25.66
+	Hs
		987613 GRB2_HUMAN (1-210): 1.15e-62: 195: 62.62		GAB1_HUMAN (172-275): 2e-30: 121: 25.66
+	Hs
		988039 GRB2_HUMAN (1-210): 1.15e-62: 195: 62.62		GAB2_HUMAN (172-267): 2.41e-30: 121: 24.76
+	Mm
		1191823 GRB2_MOUSE (1-210): 5.92e-63: 196: 63.08		Q3ZB59_MOUSE (172-267): 2.1e-29: 118: 24.76
+	Mm
		1221267 GRB2_MOUSE (1-210): 5.92e-63: 196: 63.08		GAB2_MOUSE (172-267): 1.91e-29: 118: 24.76
+	Mm
		73036 B1AT92_MOUSE (1-210): 1.03e-60: 190: 60.66		GAB2_MOUSE (172-267): 1.91e-29: 118: 24.76
+	Hs
		987801 GRB2_HUMAN (1-210): 1.15e-62: 195: 62.62		GAB3_HUMAN (172-267): 6.98e-27: 111: 29.63
+	Hs
		1111771 GRAP_HUMAN (1-210): 3.49e-56: 179: 54.17		GAB2_HUMAN (172-267): 2.41e-30: 121: 24.76
+	Hs
		902834 BLK_HUMAN (3-190): 1.12e-50: 172: 25.87		GAB1_HUMAN (172-275): 2e-30: 121: 25.66
+	Hs
		463775 LYN_HUMAN (3-199): 4e-35: 131: 25.24		PKHA5_HUMAN (69-271): 1.39e-42: 157: 18.05
+	Hs
		463776 LYN_HUMAN (3-199): 4e-35: 131: 25.24		PKHA1_HUMAN (100-271): 2.38e-44: 156: 21.26
+	Dm
		1061487 GRAP_DROME (1-211): 6.06e-61: 191: 100.00		Y34F_DROME (162-267): 2.27e-16: 81.1: 25.93
+	Hs
		463631 LYN_HUMAN (3-199): 4e-35: 131: 25.24		PKHH2_HUMAN (109-268): 2.94e-33: 130: 21.61
+	Hs
		463507 LYN_HUMAN (3-199): 4e-35: 131: 25.24		GAB1_HUMAN (172-275): 2e-30: 121: 25.66
+	Hs
		463850 LYN_HUMAN (3-199): 4e-35: 131: 25.24		GAB2_HUMAN (172-267): 2.41e-30: 121: 24.76
+	Mm
		683116 LYN_MOUSE (3-199): 4.33e-35: 131: 24.29		GAB2_MOUSE (172-267): 1.91e-29: 118: 24.76
+	Hs
		463682 LYN_HUMAN (3-199): 4e-35: 131: 25.24		GAB3_HUMAN (172-267): 6.98e-27: 111: 29.63