HitPredict

Interactor 1: CTRO (O14578)
Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)
Gene: CIT

Interactor 2: SRSF2 (Q01130)
Serine/arginine-rich splicing factor 2 (Protein PR264) (Splicing component, 35 kDa) (Splicing factor SC35) (SC-35) (Splicing factor, arginine/serine-rich 2)
Gene: SRSF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 2027 Hs			1 221
+	Hs
		148855 CTRO_HUMAN (1-2027): 0: 1212: 100.00		SF3B4_HUMAN (4-205): 1.41e-52: 176: 17.24
+	Hs
		148334 CTRO_HUMAN (1-2027): 0: 1212: 100.00		PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27
+	Hs
		149226 CTRO_HUMAN (1-2027): 0: 1212: 100.00		SRSF8_HUMAN (1-183): 4.13e-29: 111: 63.39
+	Hs
		148763 CTRO_HUMAN (1-2027): 0: 1212: 100.00		PABP4_HUMAN (5-191): 4.16e-25: 104: 13.37
+	Hs
		149282 CTRO_HUMAN (1-2027): 0: 1212: 100.00		PABP3_HUMAN (15-221): 2.48e-24: 101: 16.91
+	Hs
		149393 CTRO_HUMAN (1-2027): 0: 1212: 100.00		PUF60_HUMAN (8-108): 1.34e-23: 100: 23.76
+	Hs
		148691 CTRO_HUMAN (1-2027): 0: 1212: 100.00		TIAR_HUMAN (9-167): 1.19e-15: 76.6: 9.26
+	Hs
		148894 CTRO_HUMAN (1-2027): 0: 1212: 100.00		PAP1L_HUMAN (104-193): 4.46e-11: 63.5: 8.89
+	Rn
		1144336 AKT3_RAT (44-404): 7.24e-122: 395: 31.37		PABP1_RAT (6-202): 1.95e-41: 150: 18.27
+	Hs
		516724 KS6B2_HUMAN (57-412): 7.82e-122: 395: 30.44		PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27
+	Hs
		964075 KS6B2_HUMAN (57-412): 7.82e-122: 395: 30.44		SRSF2_HUMAN (1-221): 1.22e-43: 147: 100.00
+	Hs
		116962 SGK1_HUMAN (59-407): 8.42e-121: 390: 31.37		PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27