Interactor 1: HDAC1 (O09106)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein deacylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1
Interactor 2: SIN3B (Q62141)
Paired amphipathic helix protein Sin3b (Histone deacetylase complex subunit Sin3b) (Transcriptional corepressor Sin3b)
Gene: SIN3B
Species: Mus musculus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.76 | 1.00 | 0.873 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Hist_deacetyl~Sin3_corepress, Hist_deacetyl~Sin3a_C |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003682 - chromatin binding GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0005737 - cytoplasm and 3 others more... |
| Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
