Interactor 1: SIN3 (P22579)
Transcriptional regulatory protein SIN3
Gene: SIN3
Interactor 2: HOS1 (Q12214)
Histone deacetylase HOS1 (EC 3.5.1.98)
Gene: HOS1
Species: Saccharomyces cerevisiae S288C
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.46 | 1.00 | 0.680 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 22543816 |
| Identification Methods | pull down, two hybrid |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Hist_deacetyl~Sin3_corepress, Hist_deacetyl~Sin3a_C |
| Common GO terms | GO:0045944 - positive regulation of transcription by RNA polymerase II |
| Homologous interactions | 19 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
