HitPredict

Interactor 1: SH21A (O60880)
SH2 domain-containing protein 1A (Duncan disease SH2-protein) (Signaling lymphocytic activation molecule-associated protein) (SLAM-associated protein) (T-cell signal transduction molecule SAP)
Gene: SH2D1A

Interactor 2: SIGL7 (Q9Y286)
Sialic acid-binding Ig-like lectin 7 (Siglec-7) (Adhesion inhibitory receptor molecule 1) (AIRM-1) (CDw328) (D-siglec) (QA79 membrane protein) (p75) (CD antigen CD328)
Gene: SIGLEC7

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	19150402
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 128 Hs			1 467
+	Hs
		224533 SH21A_HUMAN (1-128): 5.2e-38: 126: 100.00		SIGL6_HUMAN (16-467): 1.87e-88: 279: 48.79
+	Hs
		439918 LCK_HUMAN (1-125): 8.6e-41: 143: 19.08		PTPRF_HUMAN (3-460): 1.55e-53: 196: 12.94
+	Hs
		463875 LYN_HUMAN (1-125): 1.58e-39: 139: 19.85		ROBO1_HUMAN (16-463): 1.55e-53: 196: 11.75
+	Mm
		59107 FYN_MOUSE (1-125): 4.05e-37: 133: 19.26		PTPRF_MOUSE (2-460): 5.48e-54: 197: 12.91
+	Hs
		440313 FYN_HUMAN (1-125): 4.26e-37: 133: 19.26		PTPRF_HUMAN (3-460): 1.55e-53: 196: 12.94
+	Hs
		463779 LYN_HUMAN (1-125): 1.58e-39: 139: 19.85		ROBO2_HUMAN (25-461): 2.31e-47: 177: 12.32
+	Hs
		463499 LYN_HUMAN (1-125): 1.58e-39: 139: 19.85		PTK7_HUMAN (22-389): 9.71e-31: 128: 12.73
+	Hs
		188586 SH21A_HUMAN (1-128): 5.2e-38: 126: 100.00		SIGL5_HUMAN (39-467): 4.87e-32: 130: 18.40
+	Hs
		557081 SRC_HUMAN (1-127): 1.8e-38: 137: 20.90		CD33_HUMAN (190-465): 3.37e-25: 108: 21.74
+	Hs
		463325 LYN_HUMAN (1-125): 1.58e-39: 139: 19.85		CD22_HUMAN (31-354): 8.92e-23: 103: 16.31
+	Hs
		629550 SHIP1_HUMAN (4-103): 1.67e-37: 136: 43.00		CD22_HUMAN (31-354): 8.92e-23: 103: 16.31
+	Hs
		440359 FYN_HUMAN (1-125): 4.26e-37: 133: 19.26		MAG_HUMAN (24-466): 1.49e-23: 105: 13.36
+	Hs
		462981 YES_HUMAN (1-127): 5.29e-40: 141: 19.40		VCAM1_HUMAN (107-363): 1.99e-19: 93.3: 18.02
+	Mm
		770704 SHIP1_MOUSE (4-103): 9.68e-37: 133: 42.00		CD22_MOUSE (20-365): 1.96e-21: 99.6: 17.05
+	Hs
		258587 SH21A_HUMAN (1-128): 5.2e-38: 126: 100.00		CD22_HUMAN (31-354): 8.92e-23: 103: 16.31
+	Hs
		629547 GRB2_HUMAN (1-123): 4.48e-35: 121: 19.69		CD22_HUMAN (31-354): 8.92e-23: 103: 16.31
+	Mm
		770697 GRB2_MOUSE (1-123): 1.99e-35: 122: 19.69		CD22_MOUSE (20-365): 1.96e-21: 99.6: 17.05
+	Hs
		187285 SHIP2_HUMAN (3-122): 1.12e-34: 128: 37.50		VCAM1_HUMAN (107-363): 1.99e-19: 93.3: 18.02
+	Hs
		557323 SRC_HUMAN (1-127): 1.8e-38: 137: 20.90		MYLK_HUMAN (232-342): 3.2e-16: 84: 21.19
+	Hs
		619714 GRB2_HUMAN (1-123): 4.48e-35: 121: 19.69		VCAM1_HUMAN (107-363): 1.99e-19: 93.3: 18.02