HitPredict

Interactor 1: H2AZ (P0C0S5)
Histone H2A.Z (H2A/z)
Gene: H2AZ1

Interactor 2: BRD8 (Q9H0E9)
Bromodomain-containing protein 8 (Skeletal muscle abundant protein) (Skeletal muscle abundant protein 2) (Thyroid hormone receptor coactivating protein of 120 kDa) (TrCP120) (p120)
Gene: BRD8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.691

Property	Details
Experiments	33961781, 28242625, 35271311, 24463511
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0006325 - chromatin organization GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 128 Hs			1 1235
+	Hs
		470008 H2AZ_HUMAN (1-128): 9.79e-62: 186: 100.00		BPTF_HUMAN (130-1222): 5.45e-42: 171: 9.55
+	Hs
		1087073 H2A2C_HUMAN (5-127): 3.47e-55: 170: 61.29		KAT2B_HUMAN (1075-1209): 2.89e-37: 154: 23.70
+	Hs
		391825 H2A1B_HUMAN (5-125): 9.18e-55: 169: 61.48		KAT2B_HUMAN (1075-1209): 2.89e-37: 154: 23.70
+	Hs
		470198 H2AZ_HUMAN (1-128): 9.79e-62: 186: 100.00		BAZ2A_HUMAN (125-815): 2.72e-30: 132: 10.85
+	Hs
		470173 H2AZ_HUMAN (1-128): 9.79e-62: 186: 100.00		BRD7_HUMAN (1005-1212): 3.07e-29: 127: 15.02
+	Hs
		1300654 H2A1A_HUMAN (5-125): 2.16e-56: 173: 61.48		BRD7_HUMAN (1005-1212): 3.07e-29: 127: 15.02
+	Hs
		1296215 H2A1H_HUMAN (5-125): 2.98e-55: 170: 61.48		BRD7_HUMAN (1005-1212): 3.07e-29: 127: 15.02
+	Hs
		998866 H2A2B_HUMAN (5-127): 9.2e-56: 171: 59.68		EP300_HUMAN (807-1211): 2.38e-27: 123: 13.66
+	Hs
		470070 H2AZ_HUMAN (1-128): 9.79e-62: 186: 100.00		PB1_HUMAN (987-1226): 1.89e-22: 107: 15.45
+	Hs
		998781 H2A2C_HUMAN (5-127): 3.47e-55: 170: 61.29		EP300_HUMAN (807-1211): 2.38e-27: 123: 13.66
+	Hs
		391671 H2A1B_HUMAN (5-125): 9.18e-55: 169: 61.48		EP300_HUMAN (807-1211): 2.38e-27: 123: 13.66
+	Hs
		469971 H2AZ_HUMAN (1-128): 9.79e-62: 186: 100.00		SMCA4_HUMAN (1057-1208): 7.26e-19: 95.5: 13.84
+	Hs
		1087035 H2A2C_HUMAN (5-127): 3.47e-55: 170: 61.29		PB1_HUMAN (987-1226): 1.89e-22: 107: 15.45
+	Hs
		391768 H2A1B_HUMAN (5-125): 9.18e-55: 169: 61.48		PB1_HUMAN (987-1226): 1.89e-22: 107: 15.45
+	Hs
		470106 H2AZ_HUMAN (1-128): 9.79e-62: 186: 100.00		PHIP_HUMAN (1059-1206): 1.19e-14: 81.5: 15.23
+	Hs
		555359 H2AX_HUMAN (5-124): 1.08e-54: 169: 61.98		SMCA4_HUMAN (1057-1208): 7.26e-19: 95.5: 13.84
+	Hs
		1087066 H2A2C_HUMAN (5-127): 3.47e-55: 170: 61.29		PHIP_HUMAN (1059-1206): 1.19e-14: 81.5: 15.23
+	Hs
		1087072 H2A2C_HUMAN (5-127): 3.47e-55: 170: 61.29		KAT2A_HUMAN (684-810): 1.1e-12: 74.9: 17.32
+	Hs
		391824 H2A1B_HUMAN (5-125): 9.18e-55: 169: 61.48		KAT2A_HUMAN (684-810): 1.1e-12: 74.9: 17.32
+	Hs
		391823 H2A1B_HUMAN (5-125): 9.18e-55: 169: 61.48		CBP_HUMAN (125-595): 9.03e-09: 62.2: 12.22