Interactor 1: TOP1 (P11387)
DNA topoisomerase 1 (EC 5.6.2.1) (DNA topoisomerase I)
Gene: TOP1

Interactor 2: NUCL (P19338)
Nucleolin (Protein C23)
Gene: NCL

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 0.60 0.685

The method score is based on:

Property Details
Experiments 9512561, 8567649, 15848144
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005694 - chromosome
GO:0005730 - nucleolus
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 765
Hs

1 710
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024