Protein: GDE1
Glycerophosphodiester phosphodiesterase 1 (Glycerophosphoinositol glycerophosphodiesterase GDE1) (EC 3.1.4.44) (Lysophospholipase D GDE1) (EC 3.1.4.-) (Membrane-interacting protein of RGS16) (RGS16-interacting membrane protein)

Gene: GDE1
Organism: Homo sapiens
Interactions: 34
UniProt ID: Q9NZC3

Gene Ontology (top 5):
GO:0004622 - phosphatidylcholine lysophospholipase activity
GO:0005886 - plasma membrane
GO:0006580 - ethanolamine metabolic process
GO:0006629 - lipid metabolic process
GO:0006644 - phospholipid metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1231477

ATLA3
Atlastin-3

3

0

High-throughput

0.638

High

1396162

LRAT2
Protein LRATD2

3

0

High-throughput

0.638

High

1453152

S4A7
Sodium bicarbonate cotransporter 3

3

0

High-throughput

0.638

High

180607

PLS1
Phospholipid scramblase 1

2

1

High-throughput

0.611

High

1027218

REEP5
Receptor expression-enhancing protein 5

3

1

High-throughput

0.609

High

322119

CDK14
Cyclin-dependent kinase 14

2

0

High-throughput

0.602

High

1134178

NTCP
Hepatic sodium/bile acid cotransporter

2

0

High-throughput

0.580

High

1064187

ADCY2
Adenylate cyclase type 2

1

1

High-throughput

0.536

High

192039

RGS16
Regulator of G-protein signaling 16

1

1

Small-scale

0.527

High

833435

RGS2
Regulator of G-protein signaling 2

1

1

Small-scale

0.527

High

770749

ADA1A
Alpha-1A adrenergic receptor

1

0

High-throughput

0.518

High

209127

CYB5B
Cytochrome b5 type B

1

0

High-throughput

0.513

High

607319

NEUM
Neuromodulin

1

0

High-throughput

0.513

High

170994

CLGN
Calmegin

1

1

High-throughput

0.494

High

387570

APOA2
Apolipoprotein A-II

1

1

High-throughput

0.489

High

1393457

REEP6
Receptor expression-enhancing protein 6

1

1

High-throughput

0.489

High

1414939

RN126
E3 ubiquitin-protein ligase RNF126

1

1

High-throughput

0.489

High

178425

NPC1
NPC intracellular cholesterol transporter 1

1

1

High-throughput

0.479

High

218871

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

485471

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

0

High-throughput

0.458

High

1453151

EPCR
Endothelial protein C receptor

1

0

High-throughput

0.458

High

769367

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

1005184

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.437

High

1326488

S22AO
Steroid transmembrane transporter SLC22A24

1

0

High-throughput

0.426

High

1363792

YLAT2
Y+L amino acid transporter 2

1

0

High-throughput

0.426

High

156358

G3PT
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

3

0

High-throughput

0.347

High

1397064

CX058
Uncharacterized protein CXorf58

3

0

High-throughput

0.345

High

1212157

ATD3C
ATPase family AAA domain-containing protein 3C

2

0

High-throughput

0.318

High

1361371

BRI3B
BRI3-binding protein

2

0

High-throughput

0.318

High

1139152

DAZP2
DAZ-associated protein 2

1

0

High-throughput

0.279

Low

1333712

UBAC2
Ubiquitin-associated domain-containing protein 2

1

0

High-throughput

0.279

Low

1447525

XPP1
Xaa-Pro aminopeptidase 1

1

0

High-throughput

0.279

Low

1415196

TM109
Voltage-gated monoatomic cation channel TMEM109

1

0

High-throughput

0.249

Low

1412215

S35A5
UDP-sugar transporter protein SLC35A5

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025