Protein: ASCL4
Achaete-scute homolog 4 (ASH-4) (hASH4) (Achaete-scute-like protein 4) (Class A basic helix-loop-helix protein 44) (bHLHa44)

Gene: ASCL4
Organism: Homo sapiens
Interactions: 56
UniProt ID: Q6XD76

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0043588 - skin development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1251019

HTF4
Transcription factor 12

5

20

Small-scale

0.933

High

587118

ITF2
Transcription factor 4

3

20

High-throughput

0.871

High

1036528

ID2
DNA-binding protein inhibitor ID-2

3

20

High-throughput

0.858

High

1116509

FHL3
Four and a half LIM domains protein 3

2

5

High-throughput

0.700

High

587490

TFE2
Transcription factor E2-alpha

1

20

High-throughput

0.691

High

832315

ID1
DNA-binding protein inhibitor ID-1

1

20

High-throughput

0.691

High

352170

MBD3
Methyl-CpG-binding domain protein 3

2

1

High-throughput

0.606

High

855656

CRK
Adapter molecule crk

2

7

High-throughput

0.576

High

370705

FOS
Protein c-Fos

1

2

High-throughput

0.515

High

396369

ESR1
Estrogen receptor

1

8

High-throughput

0.515

High

981554

RAN
GTP-binding nuclear protein Ran

1

2

High-throughput

0.515

High

1025117

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.493

High

1031914

NC2B
Protein Dr1

1

0

High-throughput

0.493

High

440602

FYN
Tyrosine-protein kinase Fyn

1

1

High-throughput

0.489

High

896799

DYN2
Dynamin-2

1

1

High-throughput

0.489

High

1050692

DYN1
Dynamin-1

1

1

High-throughput

0.489

High

1251016

ARAP3
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3

1

3

High-throughput

0.489

High

109428

G5E9A7
DM1 locus, WD repeat containing

1

7

High-throughput

0.470

High

245991

KIF1B
Kinesin-like protein KIF1B

1

1

High-throughput

0.470

High

274635

DNJB6
DnaJ homolog subfamily B member 6

1

2

High-throughput

0.470

High

415659

HSPB1
Heat shock protein beta-1

1

1

High-throughput

0.470

High

474764

VIME
Vimentin

1

1

High-throughput

0.470

High

557353

SRC
Proto-oncogene tyrosine-protein kinase Src

1

1

High-throughput

0.470

High

565641

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

2

High-throughput

0.470

High

593760

PECA1
Platelet endothelial cell adhesion molecule

1

3

High-throughput

0.470

High

650245

FGFR3
Fibroblast growth factor receptor 3

1

2

High-throughput

0.470

High

843686

HD
Huntingtin

1

2

High-throughput

0.470

High

937040

CASP6
Caspase-6

1

1

High-throughput

0.470

High

954509

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

1

High-throughput

0.470

High

987720

GRB2
Growth factor receptor-bound protein 2

1

3

High-throughput

0.470

High

996482

ACTS
Actin, alpha skeletal muscle

1

4

High-throughput

0.470

High

1165398

Q17RL8
HCG2004980, isoform CRA_e

1

2

High-throughput

0.470

High

1251014

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

4

High-throughput

0.470

High

1251015

Q86WV8
TSC complex subunit 1

1

1

High-throughput

0.470

High

1251018

OPTN
Optineurin

1

3

High-throughput

0.470

High

1251022

UBQL1
Ubiquilin-1

1

4

High-throughput

0.470

High

1251024

TF3C3
General transcription factor 3C polypeptide 3

1

6

High-throughput

0.470

High

430058

JUN
Transcription factor Jun

1

4

High-throughput

0.445

High

1251012

PDZD4
PDZ domain-containing protein 4

1

2

High-throughput

0.439

High

765640

BMI1
Polycomb complex protein BMI-1

1

2

High-throughput

0.407

High

1251020

PIP30
PSME3-interacting protein

1

0

High-throughput

0.279

Low

1251021

PCYOX
Prenylcysteine oxidase 1

1

0

High-throughput

0.279

Low

301502

WFS1
Wolframin

1

0

High-throughput

0.268

Low

407765

VWF
von Willebrand factor

1

0

High-throughput

0.268

Low

441549

CCKN
Cholecystokinin

1

0

High-throughput

0.268

Low

562156

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.268

Low

702465

CLAT
Choline O-acetyltransferase

1

0

High-throughput

0.268

Low

705424

GRN
Progranulin

1

0

High-throughput

0.268

Low

838459

GRIA1
Glutamate receptor 1

1

0

High-throughput

0.268

Low

976352

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.268

Low

1023561

CYC
Cytochrome c

1

0

High-throughput

0.268

Low

1103764

PLD1
Phospholipase D1

1

0

High-throughput

0.268

Low

1251013

PEX26
Peroxisome assembly protein 26

1

0

High-throughput

0.268

Low

1251017

APBB2
Amyloid beta precursor protein binding family B member 2

1

0

High-throughput

0.268

Low

1251023

RNF11
RING finger protein 11

1

0

High-throughput

0.268

Low

1251025

Q9Y649
GW128

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025