Protein: OPRX
Nociceptin receptor (Kappa-type 3 opioid receptor) (KOR-3) (Orphanin FQ receptor)

Gene: OPRX, OPRL1
Organism: Homo sapiens
Interactions: 96
UniProt ID: P41146

Gene Ontology (top 5):
GO:0001626 - nociceptin receptor activity
GO:0004930 - G protein-coupled receptor activity
GO:0005886 - plasma membrane
GO:0007193 - adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0007200 - phospholipase C-activating G protein-coupled receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

723013

OPRM
Mu-type opioid receptor

1

14

Small-scale

0.724

High

781083

WDFY3
WD repeat and FYVE domain-containing protein 3

1

0

High-throughput

0.656

High

781057

PNOC
Prepronociceptin [Cleaved into: Nocistatin; Nociceptin

3

0

Small-scale

0.623

High

708266

TTK
Dual specificity protein kinase TTK

1

6

High-throughput

0.618

High

781078

CERS6
Ceramide synthase 6

2

5

High-throughput

0.591

High

488147

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

2

High-throughput

0.541

High

126773

ACATN
Acetyl-coenzyme A transporter 1

1

1

High-throughput

0.536

High

154319

TR10B
Tumor necrosis factor receptor superfamily member 10B

1

3

High-throughput

0.536

High

168242

DEGS1
Sphingolipid delta(4)-desaturase DES1

1

2

High-throughput

0.536

High

175562

TM9S1
Transmembrane 9 superfamily member 1

1

4

High-throughput

0.536

High

234792

ACSL4
Long-chain-fatty-acid--CoA ligase 4

1

2

High-throughput

0.536

High

240876

S19A2
Thiamine transporter 1

1

2

High-throughput

0.536

High

309897

UCP5
Brain mitochondrial carrier protein 1

1

11

High-throughput

0.536

High

415239

ATPB
ATP synthase subunit beta, mitochondrial

1

6

High-throughput

0.536

High

530844

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

17

High-throughput

0.536

High

586009

SL9A1
Sodium/hydrogen exchanger 1

1

2

High-throughput

0.536

High

619206

AT2B4
Plasma membrane calcium-transporting ATPase 4

1

20

High-throughput

0.536

High

636834

ATPA
ATP synthase subunit alpha, mitochondrial

1

6

High-throughput

0.536

High

781047

ATPO
ATP synthase subunit O, mitochondrial

1

1

High-throughput

0.536

High

781049

KNTC1
Kinetochore-associated protein 1

1

1

High-throughput

0.536

High

781050

AT12A
Potassium-transporting ATPase alpha chain 2

1

16

High-throughput

0.536

High

781051

ACTB
Actin, cytoplasmic 1

1

6

High-throughput

0.536

High

781053

AT2B2
Plasma membrane calcium-transporting ATPase 2

1

20

High-throughput

0.536

High

781054

S20A2
Sodium-dependent phosphate transporter 2

1

1

High-throughput

0.536

High

781059

AT2B3
Plasma membrane calcium-transporting ATPase 3

1

20

High-throughput

0.536

High

781066

MRP7
ATP-binding cassette sub-family C member 10

1

1

High-throughput

0.536

High

781068

AB17B
Alpha/beta hydrolase domain-containing protein 17B

1

8

High-throughput

0.536

High

781069

LMBD2
G-protein coupled receptor-associated protein LMBRD2

1

5

High-throughput

0.536

High

781073

MFS12
Major facilitator superfamily domain-containing protein 12

1

1

High-throughput

0.536

High

781093

PAQR1
Adiponectin receptor protein 1

1

1

High-throughput

0.536

High

781095

RB39B
Ras-related protein Rab-39B

1

7

High-throughput

0.536

High

781112

ENPP4
Bis(5'-adenosyl)-triphosphatase ENPP4

1

2

High-throughput

0.536

High

179306

COPT2
Protein SLC31A2

1

0

High-throughput

0.518

High

179345

MRP4
ATP-binding cassette sub-family C member 4

1

0

High-throughput

0.513

High

781048

MAP2
Methionine aminopeptidase 2

1

0

High-throughput

0.513

High

781055

CLN3
Battenin

1

0

High-throughput

0.513

High

781090

SPPL3
Signal peptide peptidase-like 3

1

0

High-throughput

0.513

High

781100

P2RX4
P2X purinoceptor 4

1

0

High-throughput

0.513

High

781098

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

1

High-throughput

0.494

High

781110

PLLP
Plasmolipin

1

4

High-throughput

0.494

High

63310

MET15
12S rRNA N4-methylcytidine

1

2

High-throughput

0.489

High

64421

RTL8C
Retrotransposon Gag-like protein 8C

1

2

High-throughput

0.489

High

163577

BTAF1
TATA-binding protein-associated factor 172

1

3

High-throughput

0.489

High

210641

NDUB3
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3

1

1

High-throughput

0.489

High

234101

FADS1
Acyl-CoA

1

3

High-throughput

0.489

High

237791

TSN3
Tetraspanin-3

1

10

High-throughput

0.489

High

623212

AT5F1
ATP synthase F(0) complex subunit B1, mitochondrial

1

2

High-throughput

0.489

High

735873

ATPG
ATP synthase subunit gamma, mitochondrial

1

1

High-throughput

0.489

High

781052

TBA4A
Tubulin alpha-4A chain

1

7

High-throughput

0.489

High

781056

MTX1
Metaxin-1

1

4

High-throughput

0.489

High

781061

TBB8
Tubulin beta-8 chain

1

10

High-throughput

0.489

High

781062

ORML2
ORM1-like protein 2

1

2

High-throughput

0.489

High

781063

ACTBL
Beta-actin-like protein 2

1

6

High-throughput

0.489

High

781065

KMCP1
Kidney mitochondrial carrier protein 1

1

11

High-throughput

0.489

High

781067

TM164
Transmembrane protein 164

1

1

High-throughput

0.489

High

781070

ACD10
Acyl-CoA dehydrogenase family member 10

1

4

High-throughput

0.489

High

781071

SCMC1
Mitochondrial adenyl nucleotide antiporter SLC25A24

1

9

High-throughput

0.489

High

781072

RINT1
RAD50-interacting protein 1

1

2

High-throughput

0.489

High

781074

MBOA5
Lysophospholipid acyltransferase 5

1

5

High-throughput

0.489

High

781075

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

1

2

High-throughput

0.489

High

781076

HACD2
Very-long-chain

1

2

High-throughput

0.489

High

781077

THADA
tRNA

1

2

High-throughput

0.489

High

781079

DYM
Dymeclin

1

2

High-throughput

0.489

High

781080

ADCK1
AarF domain-containing protein kinase 1

1

5

High-throughput

0.489

High

781081

T126B
Complex I assembly factor TMEM126B, mitochondrial

1

2

High-throughput

0.489

High

781082

S35F2
Solute carrier family 35 member F2

1

2

High-throughput

0.489

High

781084

INT1
Integrator complex subunit 1

1

4

High-throughput

0.489

High

781085

F241A
Uncharacterized protein FAM241A

1

1

High-throughput

0.489

High

781086

NAV1
Neuron navigator 1

1

3

High-throughput

0.489

High

781087

ATLA2
Atlastin-2

1

7

High-throughput

0.489

High

781088

MFSD8
Major facilitator superfamily domain-containing protein 8

1

9

High-throughput

0.489

High

781091

CHPT1
Cholinephosphotransferase 1

1

2

High-throughput

0.489

High

781092

LGAT1
Acyl-CoA:lysophosphatidylglycerol acyltransferase 1

1

4

High-throughput

0.489

High

781094

TM186
Transmembrane protein 186

1

1

High-throughput

0.489

High

781097

CERS2
Ceramide synthase 2

1

5

High-throughput

0.489

High

781099

TLCD4
TLC domain-containing protein 4

1

1

High-throughput

0.489

High

781101

TBA1C
Tubulin alpha-1C chain

1

7

High-throughput

0.489

High

781103

PTSS2
Phosphatidylserine synthase 2

1

1

High-throughput

0.489

High

781105

TM9S3
Transmembrane 9 superfamily member 3

1

4

High-throughput

0.489

High

781106

PDS5B
Sister chromatid cohesion protein PDS5 homolog B

1

6

High-throughput

0.489

High

781107

MTFP1
Mitochondrial fission process protein 1

1

1

High-throughput

0.489

High

781108

GCP4
Gamma-tubulin complex component 4

1

7

High-throughput

0.489

High

781111

PEX16
Peroxisomal membrane protein PEX16

1

1

High-throughput

0.489

High

781064

GASP1
G-protein coupled receptor-associated sorting protein 1

1

6

Small-scale

0.457

High

781104

ACTBM
Putative beta-actin-like protein 3

1

6

High-throughput

0.407

High

210545

NDUB5
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial

1

0

High-throughput

0.279

Low

279096

ATP5H
ATP synthase subunit d, mitochondrial

1

0

High-throughput

0.279

Low

279928

ATP5L
ATP synthase subunit g, mitochondrial

1

0

High-throughput

0.279

Low

371269

ATP8
ATP synthase protein 8

1

0

High-throughput

0.279

Low

781058

STAR3
StAR-related lipid transfer protein 3

1

0

High-throughput

0.279

Low

781060

SIA4B
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2

1

0

High-throughput

0.279

Low

781089

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

1

0

High-throughput

0.279

Low

781096

OMA1
Metalloendopeptidase OMA1, mitochondrial

1

0

High-throughput

0.279

Low

781102

PGAP4
Post-GPI attachment to proteins factor 4

1

0

High-throughput

0.279

Low

781109

MGT4B
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.279

Low

483292

TPC2B
Trafficking protein particle complex subunit 2B

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024