Protein: HIBCH
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (EC 3.1.2.4) (3-hydroxyisobutyryl-coenzyme A hydrolase) (HIB-CoA hydrolase) (HIBYL-CoA-H)

Gene: HIBCH
Organism: Homo sapiens
Interactions: 41
UniProt ID: Q6NVY1

Gene Ontology (top 5):
GO:0003860 - 3-hydroxyisobutyryl-CoA hydrolase activity
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006574 - valine catabolic process
GO:0009083 - branched-chain amino acid catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

832916

ACADV
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial

3

6

High-throughput

0.667

High

1124788

OXLD1
Oxidoreductase-like domain-containing protein 1

3

0

High-throughput

0.638

High

1156940

MKRN2
E3 ubiquitin-protein ligase makorin-2

3

1

High-throughput

0.609

High

212055

GATC
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial

2

0

High-throughput

0.602

High

1086614

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

4

High-throughput

0.584

High

818158

SOX2
Transcription factor SOX-2

2

4

High-throughput

0.574

High

1153114

ETFR1
Electron transfer flavoprotein regulatory factor 1

1

1

High-throughput

0.536

High

1156942

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

6

High-throughput

0.536

High

388889

CP1A1
Cytochrome P450 1A1

1

1

High-throughput

0.489

High

555505

H2AX
Histone H2AX

1

5

High-throughput

0.489

High

1156937

DDX54
ATP-dependent RNA helicase DDX54

1

1

High-throughput

0.489

High

1156939

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

1

5

High-throughput

0.489

High

1156941

GSX1
GS homeobox 1

1

1

High-throughput

0.489

High

1156943

SCRT2
Transcriptional repressor scratch 2

1

3

High-throughput

0.489

High

227782

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

262852

CISY
Citrate synthase, mitochondrial

1

5

High-throughput

0.479

High

486553

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

4

High-throughput

0.479

High

499836

CH60
60 kDa heat shock protein, mitochondrial

1

4

High-throughput

0.479

High

799257

EFTS
Elongation factor Ts, mitochondrial

1

4

High-throughput

0.479

High

990122

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

4

High-throughput

0.479

High

1067988

PDK1
[Pyruvate dehydrogenase

1

4

High-throughput

0.479

High

1156938

FAKD4
FAST kinase domain-containing protein 4

1

7

High-throughput

0.479

High

167244

MRPP3
Mitochondrial ribonuclease P catalytic subunit

1

0

High-throughput

0.458

High

1130214

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

5

High-throughput

0.445

High

504255

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.437

High

924642

GRB2
Growth factor receptor-bound protein 2

1

4

High-throughput

0.437

High

961159

HSF1
Heat shock factor protein 1

1

2

High-throughput

0.437

High

1156934

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.437

High

1156945

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.437

High

664096

T2EB
Transcription initiation factor IIE subunit beta

2

0

High-throughput

0.328

High

1156933

T184A
Transmembrane protein 184A

2

0

High-throughput

0.328

High

63518

PRR19
Proline-rich protein 19

1

0

High-throughput

0.279

Low

319449

RPP29
Ribonuclease P protein subunit p29

1

0

High-throughput

0.279

Low

574370

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.279

Low

827229

ARRB1
Beta-arrestin-1

1

0

High-throughput

0.279

Low

960047

HXC5
Homeobox protein Hox-C5

1

0

High-throughput

0.279

Low

1156935

CIART
Circadian-associated transcriptional repressor

1

0

High-throughput

0.279

Low

1156944

CENPM
Centromere protein M

1

0

High-throughput

0.279

Low

1156946

NP1L2
Nucleosome assembly protein 1-like 2

1

0

High-throughput

0.279

Low

1156936

FLCN
Folliculin

1

0

High-throughput

0.269

Low

352137

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024