Protein: PVR
Poliovirus receptor (Nectin-like protein 5) (NECL-5) (CD antigen CD155)

Gene: PVR
Organism: Homo sapiens
Interactions: 155
UniProt ID: P15151

Gene Ontology (top 5):
GO:0001618 - virus receptor activity
GO:0001675 - acrosome assembly
GO:0002860 - positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
GO:0002891 - positive regulation of immunoglobulin mediated immune response
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

545119

TIGIT
T-cell immunoreceptor with Ig and ITIM domains

3

3

Small-scale

0.865

High

545132

NT2NA
Notch homolog 2 N-terminal-like protein A

3

20

High-throughput

0.861

High

545112

CD226
CD226 antigen

3

17

Small-scale

0.853

High

126509

QSOX1
Sulfhydryl oxidase 1

2

6

High-throughput

0.811

High

545095

RAB5B
Ras-related protein Rab-5B

2

10

High-throughput

0.811

High

545120

CDON
Cell adhesion molecule-related/down-regulated by oncogenes

2

14

High-throughput

0.811

High

119138

LEG9
Galectin-9

2

6

High-throughput

0.789

High

545113

ADIPO
Adiponectin

2

3

High-throughput

0.783

High

545173

NECT3
Nectin-3

2

18

Small-scale

0.778

High

469842

CO4A
Complement C4-A

2

0

High-throughput

0.770

High

545080

TNFL9
Tumor necrosis factor ligand superfamily member 9

2

0

High-throughput

0.770

High

545191

MTCH2
Mitochondrial carrier homolog 2

2

0

High-throughput

0.770

High

483456

PEPA4
Pepsin A-4

2

0

High-throughput

0.742

High

545105

CD47
Leukocyte surface antigen CD47

2

0

High-throughput

0.742

High

545153

S41A2
Solute carrier family 41 member 2

2

0

High-throughput

0.742

High

545081

GPDM
Glycerol-3-phosphate dehydrogenase, mitochondrial

2

3

High-throughput

0.726

High

545170

WNK1
Serine/threonine-protein kinase WNK1

1

3

High-throughput

0.698

High

450638

PAEP
Glycodelin

1

1

High-throughput

0.691

High

488114

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

2

High-throughput

0.691

High

545067

TSHR
Thyrotropin receptor

1

5

High-throughput

0.691

High

545068

LEG3
Galectin-3

1

6

High-throughput

0.691

High

545069

EPHA1
Ephrin type-A receptor 1

1

7

High-throughput

0.691

High

545075

TNFL8
Tumor necrosis factor ligand superfamily member 8

1

2

High-throughput

0.691

High

545086

RAB13
Ras-related protein Rab-13

1

6

High-throughput

0.691

High

545104

PCDH1
Protocadherin-1

1

9

High-throughput

0.691

High

545106

ITAD
Integrin alpha-D

1

5

High-throughput

0.691

High

545111

EPHA7
Ephrin type-A receptor 7

1

8

High-throughput

0.691

High

545115

MICB
MHC class I polypeptide-related sequence B

1

4

High-throughput

0.691

High

545122

SDK2
Protein sidekick-2

1

9

High-throughput

0.691

High

545146

NECT2
Nectin-2

1

18

High-throughput

0.691

High

545150

ASIC4
Acid-sensing ion channel 4

1

1

High-throughput

0.691

High

545166

ULBP3
UL16-binding protein 3

1

4

High-throughput

0.691

High

545178

CBLN4
Cerebellin-4

1

3

High-throughput

0.691

High

545185

BTNL2
Butyrophilin-like protein 2

1

18

High-throughput

0.691

High

545158

ZNT2
Proton-coupled zinc antiporter SLC30A2

4

0

High-throughput

0.668

High

545175

TMPS4
Transmembrane protease serine 4

1

9

High-throughput

0.665

High

514336

PSPC
Surfactant protein C

3

1

High-throughput

0.665

High

545108

GNA13
Guanine nucleotide-binding protein subunit alpha-13

1

0

High-throughput

0.656

High

545145

MO2R1
Cell surface glycoprotein CD200 receptor 1

1

0

High-throughput

0.656

High

545088

EP3B
Epididymal secretory protein E3-beta

2

0

High-throughput

0.655

High

545172

HHATL
Protein-cysteine N-palmitoyltransferase HHAT-like protein

2

0

High-throughput

0.655

High

545110

NECT1
Nectin-1

1

17

Small-scale

0.647

High

545102

TYRO3
Tyrosine-protein kinase receptor TYRO3

1

17

High-throughput

0.646

High

545114

NTRK3
NT-3 growth factor receptor

1

10

High-throughput

0.646

High

135919

UBE2C
Ubiquitin-conjugating enzyme E2 C

2

3

High-throughput

0.628

High

172559

GNPAT
Dihydroxyacetone phosphate acyltransferase

2

1

High-throughput

0.628

High

545076

RYK
Tyrosine-protein kinase RYK

2

18

High-throughput

0.628

High

545085

LRBA
Lipopolysaccharide-responsive and beige-like anchor protein

2

1

High-throughput

0.628

High

545098

EFNB1
Ephrin-B1

2

2

High-throughput

0.628

High

545134

NLRX1
NLR family member X1

2

3

High-throughput

0.628

High

545171

XPO5
Exportin-5

2

1

High-throughput

0.628

High

545117

CEA21
Carcinoembryonic antigen-related cell adhesion molecule 21

1

17

High-throughput

0.618

High

545176

HELLS
Lymphoid-specific helicase

1

1

High-throughput

0.618

High

177812

TMPS2
Transmembrane protease serine 2

1

9

High-throughput

0.618

High

386027

P53
Cellular tumor antigen p53

1

3

High-throughput

0.618

High

545130

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.618

High

545133

TM11B
Transmembrane protease serine 11B

1

9

High-throughput

0.618

High

545162

ACE2
Angiotensin-converting enzyme 2

1

1

Small-scale

0.618

High

545093

KR108
Keratin-associated protein 10-8

3

20

High-throughput

0.616

High

545077

TACT
T-cell surface protein tactile

2

1

High-throughput

0.611

High

66972

CRTP1
Cysteine-rich tail protein 1

2

2

High-throughput

0.606

High

305351

ZFPL1
Zinc finger protein-like 1

2

3

High-throughput

0.606

High

306752

VAMP5
Vesicle-associated membrane protein 5

2

1

High-throughput

0.606

High

545126

BRID5
BRICHOS domain-containing protein 5

2

2

High-throughput

0.606

High

545128

OLFM4
Olfactomedin-4

2

1

High-throughput

0.606

High

545135

ANR46
Ankyrin repeat domain-containing protein 46

2

10

High-throughput

0.606

High

545140

CLD19
Claudin-19

2

1

High-throughput

0.606

High

545141

ZDH22
Palmitoyltransferase ZDHHC22

2

1

High-throughput

0.606

High

545147

NINJ1
Ninjurin-1

2

1

High-throughput

0.606

High

545155

AQP10
Aquaporin-10

2

1

High-throughput

0.606

High

545181

GPC5D
G-protein coupled receptor family C group 5 member D

2

1

High-throughput

0.606

High

545182

NINJ2
Ninjurin-2

2

1

High-throughput

0.606

High

273360

PPM1B
Protein phosphatase 1B

2

0

High-throughput

0.602

High

545084

MAP2
Methionine aminopeptidase 2

2

0

High-throughput

0.602

High

545116

ALG11
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase

2

0

High-throughput

0.602

High

545139

CISD2
CDGSH iron-sulfur domain-containing protein 2

2

0

High-throughput

0.602

High

545156

XPO6
Exportin-6

2

0

High-throughput

0.602

High

545160

P4K2A
Phosphatidylinositol 4-kinase type 2-alpha

2

0

High-throughput

0.602

High

545177

LANC2
LanC-like protein 2

2

0

High-throughput

0.602

High

545190

ALG5
Dolichyl-phosphate beta-glucosyltransferase

2

0

High-throughput

0.602

High

484560

NT2NC
Notch homolog 2 N-terminal-like protein C

1

20

High-throughput

0.594

High

70795

SMIM1
Small integral membrane protein 1

2

0

High-throughput

0.580

High

136146

SCD
Stearoyl-CoA desaturase

2

0

High-throughput

0.580

High

218094

MFS11
UNC93-like protein MFSD11

2

0

High-throughput

0.580

High

545074

TSPO
Translocator protein

2

0

High-throughput

0.580

High

545087

BI1
Bax inhibitor 1

2

0

High-throughput

0.580

High

545089

T2R19
Taste receptor type 2 member 19

2

0

High-throughput

0.580

High

545100

PLP2
Proteolipid protein 2

2

0

High-throughput

0.580

High

545121

CTXN3
Cortexin-3

2

0

High-throughput

0.580

High

545123

TTMP
TPA-induced transmembrane protein

2

0

High-throughput

0.580

High

545124

SNP47
Synaptosomal-associated protein 47

2

0

High-throughput

0.580

High

545125

TMM65
Transmembrane protein 65

2

0

High-throughput

0.580

High

545137

PLPP6
Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6

2

0

High-throughput

0.580

High

545142

T229B
Transmembrane protein 229B

2

0

High-throughput

0.580

High

545148

TMM54
Transmembrane protein 54

2

0

High-throughput

0.580

High

545151

RUSF1
RUS family member 1

2

0

High-throughput

0.580

High

545161

TM147
BOS complex subunit TMEM147

2

0

High-throughput

0.580

High

319507

LY86
Lymphocyte antigen 86

1

0

High-throughput

0.578

High

545188

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

0

High-throughput

0.578

High

545107

ATR
Serine/threonine-protein kinase ATR

2

1

High-throughput

0.574

High

545131

UBP30
Ubiquitin carboxyl-terminal hydrolase 30

2

3

High-throughput

0.574

High

506865

LAMP1
Lysosome-associated membrane glycoprotein 1

2

3

High-throughput

0.571

High

545083

HXA1
Homeobox protein Hox-A1

2

5

High-throughput

0.553

High

545103

KRA11
Keratin-associated protein 1-1

2

20

High-throughput

0.553

High

545136

KRA13
Keratin-associated protein 1-3

2

20

High-throughput

0.553

High

545159

TMM79
Transmembrane protein 79

2

1

High-throughput

0.553

High

545163

KRA93
Keratin-associated protein 9-3

2

20

High-throughput

0.553

High

545164

KRA33
Keratin-associated protein 3-3

2

1

High-throughput

0.553

High

545165

KRA31
Keratin-associated protein 3-1

2

1

High-throughput

0.553

High

545189

INSI2
Insulin-induced gene 2 protein

2

2

High-throughput

0.553

High

217629

EFNA2
Ephrin-A2

1

2

High-throughput

0.536

High

545070

ITA6
Integrin alpha-6

1

2

High-throughput

0.536

High

545078

STAT3
Signal transducer and activator of transcription 3

1

1

High-throughput

0.536

High

545090

CD81
CD81 antigen

1

10

Small-scale

0.536

High

545099

IL5RA
Interleukin-5 receptor subunit alpha

1

7

High-throughput

0.536

High

545157

GML
Glycosyl-phosphatidylinositol-anchored molecule-like protein

1

2

High-throughput

0.536

High

545183

SLAF8
SLAM family member 8

1

17

High-throughput

0.536

High

545186

FBX2
F-box only protein 2

1

8

High-throughput

0.536

High

545187

CLC4A
C-type lectin domain family 4 member A

1

9

High-throughput

0.536

High

545096

DYLT1
Dynein light chain Tctex-type 1

1

0

Small-scale

0.529

High

545092

KR107
Keratin-associated protein 10-7

1

20

High-throughput

0.523

High

545094

KR109
Keratin-associated protein 10-9

1

20

High-throughput

0.523

High

545180

PA2G3
Group 3 secretory phospholipase A2

1

0

High-throughput

0.518

High

155520

TNPO2
Transportin-2

1

0

High-throughput

0.513

High

545072

CTNA2
Catenin alpha-2

1

0

High-throughput

0.513

High

545073

HMOX2
Heme oxygenase 2

1

0

High-throughput

0.513

High

545082

MSS4
Guanine nucleotide exchange factor MSS4

1

0

High-throughput

0.513

High

545184

P2RX2
P2X purinoceptor 2

1

0

High-throughput

0.513

High

484876

TM276
Transmembrane protein 276

1

0

High-throughput

0.493

High

545071

COT2
COUP transcription factor 2

1

6

High-throughput

0.489

High

545152

FXL20
F-box/LRR-repeat protein 20

1

1

High-throughput

0.489

High

472

NBPFJ
Neuroblastoma breakpoint family member 19

1

2

High-throughput

0.481

High

372987

VTNC
Vitronectin

1

0

Small-scale

0.480

High

204994

TGON2
Trans-Golgi network integral membrane protein 2

1

8

High-throughput

0.479

High

545097

RNF4
E3 ubiquitin-protein ligase RNF4

1

5

High-throughput

0.479

High

545101

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

6

Small-scale

0.479

High

545127

LMBRL
Protein LMBR1L

1

4

High-throughput

0.479

High

545174

FBX6
F-box only protein 6

1

8

High-throughput

0.479

High

545179

T106B
Transmembrane protein 106B

1

3

High-throughput

0.479

High

545091

KR103
Keratin-associated protein 10-3

1

20

High-throughput

0.439

High

545192

AP1M2
AP-1 complex subunit mu-2

1

1

Small-scale

0.439

High

545169

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

4

Small-scale

0.437

High

253771

XYLK
Glycosaminoglycan xylosylkinase

2

0

High-throughput

0.328

High

545079

RFC3
Replication factor C subunit 3

2

0

High-throughput

0.328

High

545129

MMS22
Protein MMS22-like

2

0

High-throughput

0.328

High

545144

RETR2
Reticulophagy regulator 2

2

0

High-throughput

0.328

High

545168

ARV1
Protein ARV1

2

0

High-throughput

0.328

High

545109

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

0

High-throughput

0.316

High

545138

SYS1
Protein SYS1 homolog

2

0

High-throughput

0.316

High

545143

CYAC3
Lysosomal membrane ascorbate-dependent ferrireductase CYB561A3

2

0

High-throughput

0.316

High

545149

S35B4
Nucleotide sugar transporter SLC35B4

2

0

High-throughput

0.316

High

545154

ZDH15
Palmitoyltransferase ZDHHC15

2

0

High-throughput

0.316

High

545167

TM6S2
Transmembrane 6 superfamily member 2

2

0

High-throughput

0.316

High

217771

ORC4
Origin recognition complex subunit 4

1

0

High-throughput

0.279

Low

545118

KRA63
Keratin-associated protein 6-3

1

0

High-throughput

0.268

Low


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Last updated: 15 Jul 2024