Protein: SGCA
Alpha-sarcoglycan (Alpha-SG) (50 kDa dystrophin-associated glycoprotein) (50DAG) (Adhalin) (Dystroglycan-2)

Gene: SGCA
Organism: Homo sapiens
Interactions: 107
UniProt ID: Q16586

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005509 - calcium ion binding
GO:0005789 - endoplasmic reticulum membrane
GO:0005856 - cytoskeleton
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

226781

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

6

1

High-throughput

0.679

High

1159218

PTPRU
Receptor-type tyrosine-protein phosphatase U

3

2

High-throughput

0.667

High

1087052

FSTL1
Follistatin-related protein 1

3

0

High-throughput

0.641

High

963568

DAD1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

3

0

High-throughput

0.638

High

1159253

MAN1
Inner nuclear membrane protein Man1

3

1

High-throughput

0.609

High

641302

PGS1
Biglycan

1

1

Small-scale

0.561

High

1159220

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

2

1

High-throughput

0.553

High

389398

FINC
Fibronectin

1

2

High-throughput

0.541

High

522669

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

2

High-throughput

0.536

High

565625

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

1

High-throughput

0.536

High

787301

ACV1B
Activin receptor type-1B

1

2

High-throughput

0.536

High

1023338

AT2C1
Calcium-transporting ATPase type 2C member 1

1

1

High-throughput

0.536

High

1102707

PTPRS
Receptor-type tyrosine-protein phosphatase S

1

2

High-throughput

0.536

High

1120614

DAG1
Dystroglycan 1

1

2

High-throughput

0.536

High

1159199

MICA
MHC class I polypeptide-related sequence A

1

1

High-throughput

0.536

High

1159231

TMM59
Transmembrane protein 59

1

1

High-throughput

0.536

High

1159243

CC50A
Cell cycle control protein 50A

1

1

High-throughput

0.536

High

1159248

TM59L
Transmembrane protein 59-like

1

1

High-throughput

0.536

High

1159254

BIG2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2

1

1

High-throughput

0.536

High

1159255

BIG1
Brefeldin A-inhibited guanine nucleotide-exchange protein 1

1

1

High-throughput

0.536

High

1159249

ITBP2
Integrin beta-1-binding protein 2

1

0

High-throughput

0.518

High

788933

TGFR2
TGF-beta receptor type-2

1

2

High-throughput

0.515

High

61109

T131L
Transmembrane protein 131-like

1

0

High-throughput

0.513

High

166919

MGST3
Glutathione S-transferase 3, mitochondrial

1

0

High-throughput

0.513

High

178551

PLCB
1-acyl-sn-glycerol-3-phosphate acyltransferase beta

1

0

High-throughput

0.513

High

194827

KCNN4
Intermediate conductance calcium-activated potassium channel protein 4

1

0

High-throughput

0.513

High

249856

STX10
Syntaxin-10

1

0

High-throughput

0.513

High

271709

HIP1R
Huntingtin-interacting protein 1-related protein

1

0

High-throughput

0.513

High

275521

RTN2
Reticulon-2

1

0

High-throughput

0.513

High

316502

B3GA3
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3

1

0

High-throughput

0.513

High

341425

CDS2
Phosphatidate cytidylyltransferase 2

1

0

High-throughput

0.513

High

418160

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.513

High

552014

ADT1
ADP/ATP translocase 1

1

0

High-throughput

0.513

High

556113

CADH1
Cadherin-1

1

0

High-throughput

0.513

High

640177

EPHA1
Ephrin type-A receptor 1

1

0

High-throughput

0.513

High

719714

HLAF
HLA class I histocompatibility antigen, alpha chain F

1

0

High-throughput

0.513

High

749611

ACSL1
Long-chain-fatty-acid--CoA ligase 1

1

0

High-throughput

0.513

High

800213

VKGC
Vitamin K-dependent gamma-carboxylase

1

0

High-throughput

0.513

High

834661

TNFL9
Tumor necrosis factor ligand superfamily member 9

1

0

High-throughput

0.513

High

876685

HSP13
Heat shock 70 kDa protein 13

1

0

High-throughput

0.513

High

878028

AGRE5
Adhesion G protein-coupled receptor E5

1

0

High-throughput

0.513

High

896764

DYN2
Dynamin-2

1

0

High-throughput

0.513

High

936055

PAR2
Proteinase-activated receptor 2

1

0

High-throughput

0.513

High

1055315

APLP2
Amyloid beta precursor like protein 2

1

0

High-throughput

0.513

High

1062167

PCDH1
Protocadherin-1

1

0

High-throughput

0.513

High

1062976

DDR1
Epithelial discoidin domain-containing receptor 1

1

0

High-throughput

0.513

High

1105731

ADAM9
Disintegrin and metalloproteinase domain-containing protein 9

1

0

High-throughput

0.513

High

1154039

MSMO1
Methylsterol monooxygenase 1

1

0

High-throughput

0.513

High

1159198

PRSS8
Prostasin

1

0

High-throughput

0.513

High

1159200

ALG11
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase

1

0

High-throughput

0.513

High

1159201

GP107
Protein GPR107

1

0

High-throughput

0.513

High

1159206

TMC6
Transmembrane channel-like protein 6

1

0

High-throughput

0.513

High

1159208

NIN
Ninein

1

0

High-throughput

0.513

High

1159211

DGLB
Diacylglycerol lipase-beta

1

0

High-throughput

0.513

High

1159213

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.513

High

1159214

TLC3A
TLC domain-containing protein 3A

1

0

High-throughput

0.513

High

1159219

PIGT
GPI-anchor transamidase component PIGT

1

0

High-throughput

0.513

High

1159221

BSCL2
Seipin

1

0

High-throughput

0.513

High

1159225

MBOA7
Membrane-bound acylglycerophosphatidylinositol O-acyltransferase MBOAT7

1

0

High-throughput

0.513

High

1159227

MYADM
Myeloid-associated differentiation marker

1

0

High-throughput

0.513

High

1159228

SORT
Sortilin

1

0

High-throughput

0.513

High

1159230

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

0

High-throughput

0.513

High

1159232

MAGT1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1

1

0

High-throughput

0.513

High

1159234

DOCK5
Dedicator of cytokinesis protein 5

1

0

High-throughput

0.513

High

1159237

LPAR2
Lysophosphatidic acid receptor 2

1

0

High-throughput

0.513

High

1159239

ABCB6
ATP-binding cassette sub-family B member 6

1

0

High-throughput

0.513

High

1159245

CKLF6
CKLF-like MARVEL transmembrane domain-containing protein 6

1

0

High-throughput

0.513

High

1159246

NSMA3
Sphingomyelin phosphodiesterase 4

1

0

High-throughput

0.513

High

1159247

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

0

High-throughput

0.513

High

1159251

XCT
Cystine/glutamate transporter

1

0

High-throughput

0.513

High

1159252

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.513

High

895568

SERPH
Serpin H1

1

0

High-throughput

0.493

High

1159229

S2533
Solute carrier family 25 member 33

1

1

High-throughput

0.489

High

1159238

TPC
Mitochondrial thiamine pyrophosphate carrier

1

1

High-throughput

0.489

High

228082

PM34
Peroxisomal membrane protein PMP34

1

2

High-throughput

0.437

High

1159210

LEMD2
LEM domain-containing protein 2

1

1

High-throughput

0.437

High

1159207

GP180
Integral membrane protein GPR180

3

0

High-throughput

0.347

High

536255

PPAL
Lysosomal acid phosphatase

2

0

High-throughput

0.318

High

639744

TAF1
Transcription initiation factor TFIID subunit 1

1

0

High-throughput

0.282

High

71327

F1712
Protein FAM171A2

1

0

High-throughput

0.279

Low

165585

SCAM3
Secretory carrier-associated membrane protein 3

1

0

High-throughput

0.279

Low

876253

NMU
Neuromedin-U [Cleaved into: Neuromedin precursor-related peptide 36

1

0

High-throughput

0.279

Low

941910

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.279

Low

1133203

STAR3
StAR-related lipid transfer protein 3

1

0

High-throughput

0.279

Low

1147519

UBE3C
Ubiquitin-protein ligase E3C

1

0

High-throughput

0.279

Low

1159202

RN213
E3 ubiquitin-protein ligase RNF213

1

0

High-throughput

0.279

Low

1159203

GL8D1
Glycosyltransferase 8 domain-containing protein 1

1

0

High-throughput

0.279

Low

1159204

INT5
Integrator complex subunit 5

1

0

High-throughput

0.279

Low

1159205

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

0

High-throughput

0.279

Low

1159209

RN149
E3 ubiquitin-protein ligase RNF149

1

0

High-throughput

0.279

Low

1159212

MROH1
Maestro heat-like repeat-containing protein family member 1

1

0

High-throughput

0.279

Low

1159215

THEM6
Protein THEM6

1

0

High-throughput

0.279

Low

1159216

ELYS
Protein ELYS

1

0

High-throughput

0.279

Low

1159217

TM9S4
Transmembrane 9 superfamily member 4

1

0

High-throughput

0.279

Low

1159222

MYO19
Unconventional myosin-XIX

1

0

High-throughput

0.279

Low

1159223

INT4
Integrator complex subunit 4

1

0

High-throughput

0.279

Low

1159224

S35E1
Solute carrier family 35 member E1

1

0

High-throughput

0.279

Low

1159226

SFXN2
Sideroflexin-2

1

0

High-throughput

0.279

Low

1159233

HEAT1
HEAT repeat-containing protein 1

1

0

High-throughput

0.279

Low

1159235

XPO5
Exportin-5

1

0

High-throughput

0.279

Low

1159236

S38AA
Solute carrier family 38 member 10

1

0

High-throughput

0.279

Low

1159240

PYRG2
CTP synthase 2

1

0

High-throughput

0.279

Low

1159241

SLX9
Ribosome biogenesis protein SLX9 homolog

1

0

High-throughput

0.279

Low

1159242

UFSP2
Ufm1-specific protease 2

1

0

High-throughput

0.279

Low

1159244

DJC11
DnaJ homolog subfamily C member 11

1

0

High-throughput

0.279

Low

931529

RD23A
UV excision repair protein RAD23 homolog A

1

0

High-throughput

0.268

Low

1159250

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025