Protein: HAIR
Lysine-specific demethylase hairless (EC 1.14.11.65) ([histone H3]-dimethyl-L-lysine(9) demethylase hairless)

Gene: HAIR, HR
Organism: Homo sapiens
Interactions: 49
UniProt ID: O43593

Gene Ontology (top 5):
GO:0000118 - histone deacetylase complex
GO:0000785 - chromatin
GO:0003712 - transcription coregulator activity
GO:0003714 - transcription corepressor activity
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

221023

VDR
Vitamin D3 receptor

2

7

Small-scale

0.629

High

221027

HXA1
Homeobox protein Hox-A1

2

1

High-throughput

0.606

High

221047

SPAG8
Sperm-associated antigen 8

2

1

High-throughput

0.606

High

221033

HDAC1
Histone deacetylase 1

2

7

Small-scale

0.584

High

221028

GEMI4
Gem-associated protein 4

2

0

High-throughput

0.580

High

221032

INCA1
Protein INCA1

2

0

High-throughput

0.580

High

221053

ZMY12
Zinc finger MYND domain-containing protein 12

2

0

High-throughput

0.580

High

221054

CFA68
Cilia- and flagella-associated protein 68

2

0

High-throughput

0.580

High

221057

AMMR1
Nuclear protein AMMECR1

2

0

High-throughput

0.580

High

221035

KR151
Keratin-associated protein 15-1

2

1

High-throughput

0.553

High

221037

KR132
Keratin-associated protein 13-2

2

1

High-throughput

0.553

High

221050

KRA33
Keratin-associated protein 3-3

2

1

High-throughput

0.553

High

221051

KRA31
Keratin-associated protein 3-1

2

1

High-throughput

0.553

High

221014

TBL1X
F-box-like/WD repeat-containing protein TBL1X

1

2

High-throughput

0.541

High

221019

RARA
Retinoic acid receptor alpha

1

8

High-throughput

0.541

High

221021

RARB
Retinoic acid receptor beta

1

8

High-throughput

0.541

High

221024

TRI27
Zinc finger protein RFP

1

1

High-throughput

0.541

High

221016

CYTA
Cystatin-A

1

1

High-throughput

0.536

High

221052

TBL1R
F-box-like/WD repeat-containing protein TBL1XR1

1

2

High-throughput

0.536

High

221026

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

0

High-throughput

0.513

High

221031

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

1

0

High-throughput

0.513

High

221015

ANT3
Antithrombin-III

1

1

High-throughput

0.489

High

221030

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

1

High-throughput

0.489

High

221025

KPCA
Protein kinase C alpha type

1

0

Small-scale

0.480

High

188112

HDAC3
Histone deacetylase 3

1

7

Small-scale

0.479

High

221022

THA
Thyroid hormone receptor alpha

1

5

Small-scale

0.479

High

221046

HDAC2
Histone deacetylase 2

1

7

Small-scale

0.479

High

221055

HDAC5
Histone deacetylase 5

1

8

Small-scale

0.479

High

221040

Q86WV8
TSC complex subunit 1

1

1

High-throughput

0.470

High

221048

Q9BS75
Kelch-like protein 20

1

2

High-throughput

0.470

High

221017

P53
Cellular tumor antigen p53

1

0

Small-scale

0.458

High

221045

ESR2
Estrogen receptor beta

1

10

High-throughput

0.445

High

221044

TSC1
Hamartin

1

2

High-throughput

0.439

High

221056

KLH20
Kelch-like protein 20

1

2

High-throughput

0.439

High

70042

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

192041

PA2GX
Group 10 secretory phospholipase A2

2

0

High-throughput

0.316

High

221013

SPY3
Protein sprouty homolog 3

2

0

High-throughput

0.316

High

221020

RET3
Retinol-binding protein 3

2

0

High-throughput

0.316

High

221038

ACTMP
Actin maturation protease

2

0

High-throughput

0.316

High

221041

KR111
Keratin-associated protein 11-1

2

0

High-throughput

0.316

High

221043

F168A
Protein FAM168A

2

0

High-throughput

0.316

High

221049

CNFN
Cornifelin

2

0

High-throughput

0.316

High

221058

ATP23
Mitochondrial inner membrane protease ATP23 homolog

2

0

High-throughput

0.316

High

221039

IQGA3
Ras GTPase-activating-like protein IQGAP3

1

0

High-throughput

0.279

Low

221034

KRA63
Keratin-associated protein 6-3

1

0

High-throughput

0.268

Low

221042

ABHDB
sn-1-specific diacylglycerol lipase ABHD11

1

0

High-throughput

0.268

Low

221029

YPEL3
Protein yippee-like 3

1

0

High-throughput

0.251

Low

221036

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.251

Low

221018

IGLC1
Immunoglobulin lambda constant 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025