Protein: OGG1
N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase (EC 3.2.2.-); DNA-(apurinic or apyrimidinic site) lyase (AP lyase) (EC 4.2.99.18)]

Gene: OGG1
Organism: Homo sapiens
Interactions: 17
UniProt ID: O15527

Gene Ontology (top 5):
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0003684 - damaged DNA binding
GO:0003677 - DNA binding
GO:0004519 - endonuclease activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

193358

RAD1
Cell cycle checkpoint protein RAD1

1

0

Small-scale

0.537

High

193359

HUS1
Checkpoint protein HUS1

1

0

Small-scale

0.537

High

193361

KPCA
Protein kinase C alpha type

1

0

Small-scale

0.537

High

193373

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

0

Small-scale

0.537

High

193374

RAD9A
Cell cycle checkpoint control protein RAD9A

1

0

Small-scale

0.537

High

193362

XRCC1
DNA repair protein XRCC1

1

0

Small-scale

0.504

High

193366

RUXF
Small nuclear ribonucleoprotein F

1

0

High-throughput

0.493

High

193367

XPC
DNA repair protein complementing XP-C cells

1

0

Small-scale

0.480

High

193368

ERCC6
DNA excision repair protein ERCC-6

1

1

Small-scale

0.479

High

193369

ERCC8
DNA excision repair protein ERCC-8

1

0

Small-scale

0.458

High

193370

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

0

Small-scale

0.458

High

193364

APJ
Apelin receptor

2

0

High-throughput

0.328

High

193360

SCG1
Secretogranin-1

1

0

High-throughput

0.282

High

193371

NHLC3
NHL repeat-containing protein 3

1

0

High-throughput

0.279

Low

193363

CD80
T-lymphocyte activation antigen CD80

1

0

High-throughput

0.232

Low

193365

PTH2R
Parathyroid hormone 2 receptor

1

0

High-throughput

0.232

Low

193372

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025