Protein: ZN444
Zinc finger protein 444 (Endothelial zinc finger protein 2) (EZF-2) (Zinc finger and SCAN domain-containing protein 17)

Gene: ZN444, ZNF444
Organism: Homo sapiens
Interactions: 132
UniProt ID: Q8N0Y2

Gene Ontology (top 5):
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

600333

ZNF24
Zinc finger protein 24

5

20

High-throughput

0.926

High

1153640

ZKSC8
Zinc finger protein with KRAB and SCAN domains 8

5

20

High-throughput

0.926

High

944193

SCND1
SCAN domain-containing protein 1

3

20

High-throughput

0.861

High

1152371

ZN174
Zinc finger protein 174

3

20

High-throughput

0.861

High

1246834

SCND3
SCAN domain-containing protein 3

3

20

High-throughput

0.861

High

1291994

ZSC30
Zinc finger and SCAN domain-containing protein 30

3

20

High-throughput

0.861

High

1322329

ZN397
Zinc finger protein 397

3

20

High-throughput

0.861

High

1322337

ZKSC4
Zinc finger protein with KRAB and SCAN domains 4

3

20

High-throughput

0.861

High

1322352

ZKSC3
Zinc finger protein with KRAB and SCAN domains 3

3

20

High-throughput

0.861

High

1322361

ZN446
Zinc finger protein 446

3

20

High-throughput

0.861

High

1322362

ZSC32
Zinc finger and SCAN domain-containing protein 32

3

19

High-throughput

0.861

High

171896

ZN263
Zinc finger protein 263

2

20

High-throughput

0.811

High

1322370

ZN232
Zinc finger protein 232

2

20

High-throughput

0.811

High

517591

ZSC22
Zinc finger and SCAN domain-containing protein 22

2

20

High-throughput

0.783

High

1322349

SRPK1
SRSF protein kinase 1

1

5

High-throughput

0.710

High

270829

ROCK2
Rho-associated protein kinase 2

1

2

High-throughput

0.691

High

600428

ZKSC1
Zinc finger protein with KRAB and SCAN domains 1

1

20

High-throughput

0.691

High

691790

MK03
Mitogen-activated protein kinase 3

1

2

High-throughput

0.691

High

703643

MK01
Mitogen-activated protein kinase 1

1

2

High-throughput

0.691

High

704475

MZF1
Myeloid zinc finger 1

1

20

High-throughput

0.691

High

1322375

STK24
Serine/threonine-protein kinase 24

1

9

High-throughput

0.691

High

977540

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

3

7

High-throughput

0.667

High

1113656

CUL3
Cullin-3

3

20

High-throughput

0.667

High

1322360

RBM22
Pre-mRNA-splicing factor RBM22

3

2

High-throughput

0.667

High

603306

KPCA
Protein kinase C alpha type

1

4

High-throughput

0.665

High

1322333

CHC10
Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial

2

1

High-throughput

0.628

High

385954

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

2

20

High-throughput

0.621

High

1322328

ZN579
Zinc finger protein 579

1

19

High-throughput

0.618

High

1322345

KLH15
Kelch-like protein 15

2

6

High-throughput

0.611

High

230059

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

3

4

High-throughput

0.609

High

1156542

CCDC6
Coiled-coil domain-containing protein 6

3

3

High-throughput

0.609

High

1322342

SAHH3
Adenosylhomocysteinase 3

3

4

High-throughput

0.609

High

1322358

STRN4
Striatin-4

3

4

High-throughput

0.609

High

192382

GSC2
Homeobox protein goosecoid-2

2

17

High-throughput

0.606

High

1096458

PAK1
Serine/threonine-protein kinase PAK 1

1

8

High-throughput

0.594

High

593260

LIPP
Pancreatic triacylglycerol lipase

2

1

High-throughput

0.574

High

1086424

FBLN3
EGF-containing fibulin-like extracellular matrix protein 1

2

20

High-throughput

0.574

High

1278535

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

2

2

High-throughput

0.574

High

1322330

GP156
Probable G-protein coupled receptor 156

2

1

High-throughput

0.574

High

1322340

VWCE
von Willebrand factor C and EGF domain-containing protein

2

20

High-throughput

0.574

High

1322359

TNR19
Tumor necrosis factor receptor superfamily member 19

2

2

High-throughput

0.574

High

1206094

TGO1
Transport and Golgi organization protein 1 homolog

2

1

High-throughput

0.558

High

65093

GG6L9
Golgin subfamily A member 6-like protein 9

2

17

High-throughput

0.553

High

950324

KR107
Keratin-associated protein 10-7

2

20

High-throughput

0.553

High

950576

KR108
Keratin-associated protein 10-8

2

20

High-throughput

0.553

High

1322336

DVL3
Segment polarity protein dishevelled homolog DVL-3

2

16

High-throughput

0.553

High

683740

PTX3
Pentraxin-related protein PTX3

2

2

High-throughput

0.549

High

183276

LAMA5
Laminin subunit alpha-5

1

20

High-throughput

0.536

High

634518

LMNB1
Lamin-B1

1

20

High-throughput

0.536

High

1047626

NOTC2
Neurogenic locus notch homolog protein 2

1

20

High-throughput

0.536

High

1067499

EP300
Histone acetyltransferase p300

1

5

High-throughput

0.536

High

1116426

FHL1
Four and a half LIM domains protein 1

1

20

High-throughput

0.536

High

1322341

RNF31
E3 ubiquitin-protein ligase RNF31

1

20

High-throughput

0.536

High

1322344

TRI47
E3 ubiquitin-protein ligase TRIM47

1

20

High-throughput

0.536

High

1322346

PUS7
Pseudouridylate synthase 7 homolog

1

1

High-throughput

0.536

High

1322348

ERBIN
Erbin

1

6

High-throughput

0.536

High

1322374

NDK7
Nucleoside diphosphate kinase homolog 7

1

1

High-throughput

0.536

High

216747

HTRA2
Serine protease HTRA2, mitochondrial

1

4

High-throughput

0.515

High

384480

CRYAA
Alpha-crystallin A chain

1

3

High-throughput

0.515

High

843753

HD
Huntingtin

1

8

High-throughput

0.515

High

966597

1433G
14-3-3 protein gamma

1

17

High-throughput

0.515

High

986560

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

3

High-throughput

0.515

High

1139760

SETB1
Histone-lysine N-methyltransferase SETDB1

1

11

High-throughput

0.515

High

1289860

Q86V38
Atrophin 1

1

1

High-throughput

0.515

High

1322331

LMO3
LIM domain only protein 3

1

17

High-throughput

0.515

High

1322335

KAT5
Histone acetyltransferase KAT5

1

5

High-throughput

0.515

High

1322338

OPTN
Optineurin

1

8

High-throughput

0.515

High

1322372

RNF11
RING finger protein 11

1

2

High-throughput

0.515

High

61750

SBNO1
Protein strawberry notch homolog 1

1

0

High-throughput

0.513

High

353878

BCL10
B-cell lymphoma/leukemia 10

1

0

High-throughput

0.513

High

410484

PRM2
Protamine-2

1

0

High-throughput

0.513

High

562620

RINI
Ribonuclease inhibitor

1

0

High-throughput

0.513

High

582103

PGAM2
Phosphoglycerate mutase 2

1

0

High-throughput

0.513

High

1107568

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

0

High-throughput

0.513

High

1322339

NMD3
60S ribosomal export protein NMD3

1

0

High-throughput

0.513

High

1322363

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.513

High

49531

SHSA3
Protein shisa-3 homolog

1

1

High-throughput

0.489

High

270158

LRP3
Low-density lipoprotein receptor-related protein 3

1

17

High-throughput

0.489

High

654533

FBLN1
Fibulin-1

1

20

High-throughput

0.489

High

1013312

HTRA4
Serine protease HTRA4

1

6

High-throughput

0.489

High

1022550

PGBM
Basement membrane-specific heparan sulfate proteoglycan core protein

1

3

High-throughput

0.489

High

1132103

LTBP2
Latent-transforming growth factor beta-binding protein 2

1

20

High-throughput

0.489

High

1244731

KLD10
Kelch domain-containing protein 10

1

6

High-throughput

0.489

High

1247795

KLH24
Kelch-like protein 24

1

5

High-throughput

0.489

High

1280951

CTU1
Cytoplasmic tRNA 2-thiolation protein 1

1

1

High-throughput

0.489

High

1294359

FRAS1
Extracellular matrix organizing protein FRAS1

1

20

High-throughput

0.489

High

1322327

RHG18
Rho GTPase-activating protein 18

1

12

High-throughput

0.489

High

1322332

DCA11
DDB1- and CUL4-associated factor 11

1

1

High-throughput

0.489

High

1322343

KAZD1
Kazal-type serine protease inhibitor domain-containing protein 1

1

5

High-throughput

0.489

High

1322347

O52B2
Olfactory receptor 52B2

1

1

High-throughput

0.489

High

1322351

KLDC3
Kelch domain-containing protein 3

1

6

High-throughput

0.489

High

1322354

LRRC1
Leucine-rich repeat-containing protein 1

1

6

High-throughput

0.489

High

1322355

BTBD1
BTB/POZ domain-containing protein 1

1

11

High-throughput

0.489

High

1322364

KLHL8
Kelch-like protein 8

1

5

High-throughput

0.489

High

1322365

KLHL9
Kelch-like protein 9

1

6

High-throughput

0.489

High

1322366

KLH42
Kelch-like protein 42

1

6

High-throughput

0.489

High

1322367

KLH13
Kelch-like protein 13

1

7

High-throughput

0.489

High

1322368

FBLN5
Fibulin-5

1

20

High-throughput

0.489

High

1322371

NISCH
Nischarin

1

5

High-throughput

0.489

High

1322373

IPP
Actin-binding protein IPP

1

5

High-throughput

0.489

High

303164

RGS20
Regulator of G-protein signaling 20

1

7

High-throughput

0.479

High

404216

GCR
Glucocorticoid receptor

1

15

High-throughput

0.479

High

1045503

TF65
Transcription factor p65

1

2

High-throughput

0.479

High

1092899

STRN3
Striatin-3

1

9

High-throughput

0.479

High

1322369

ZRAN1
Ubiquitin thioesterase ZRANB1

1

15

High-throughput

0.479

High

47373

A0A6Q8PF08
Peripheral myelin protein 22

1

1

High-throughput

0.470

High

109459

G5E9A7
DM1 locus, WD repeat containing

1

11

High-throughput

0.470

High

246035

KIF1B
Kinesin-like protein KIF1B

1

6

High-throughput

0.470

High

301551

WFS1
Wolframin

1

5

High-throughput

0.470

High

570498

GFAP
Glial fibrillary acidic protein

1

13

High-throughput

0.470

High

622213

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

1

3

High-throughput

0.470

High

705460

GRN
Progranulin

1

5

High-throughput

0.470

High

833312

PERI
Peripherin

1

13

High-throughput

0.470

High

954535

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

3

High-throughput

0.470

High

1279628

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

20

High-throughput

0.470

High

1292904

Q86WV8
TSC complex subunit 1

1

1

High-throughput

0.470

High

1322334

KLK6
Kallikrein-6

1

1

High-throughput

0.470

High

946504

YBEY
Endoribonuclease YbeY

1

0

High-throughput

0.458

High

765700

BMI1
Polycomb complex protein BMI-1

1

13

High-throughput

0.445

High

75571

B3KSW4
Regulator of G protein signaling 20

1

7

High-throughput

0.407

High

166170

AIM2
Interferon-inducible protein AIM2

1

0

High-throughput

0.279

Low

554814

ODBA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

1

0

High-throughput

0.279

Low

898112

LRBA
Lipopolysaccharide-responsive and beige-like anchor protein

1

0

High-throughput

0.279

Low

1180680

CTU2
Cytoplasmic tRNA 2-thiolation protein 2

1

0

High-throughput

0.279

Low

1206288

PSMG4
Proteasome assembly chaperone 4

1

0

High-throughput

0.279

Low

1308551

NUDC3
NudC domain-containing protein 3

1

0

High-throughput

0.279

Low

1315336

THNS1
Threonine synthase-like 1

1

0

High-throughput

0.279

Low

1322350

CMS1
Protein CMSS1

1

0

High-throughput

0.279

Low

1322353

PSMG3
Proteasome assembly chaperone 3

1

0

High-throughput

0.279

Low

1322356

GATA
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial

1

0

High-throughput

0.279

Low

1322357

NT5D2
5'-nucleotidase domain-containing protein 2

1

0

High-throughput

0.279

Low

167621

GIPC1
PDZ domain-containing protein GIPC1

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025