Protein: MUTA
Methylmalonyl-CoA mutase, mitochondrial (MCM) (EC 5.4.99.2) (Methylmalonyl-CoA isomerase)

Gene: MUTA, MMUT
Organism: Homo sapiens
Interactions: 53
UniProt ID: P22033

Gene Ontology (top 5):
GO:0003924 - GTPase activity
GO:0004494 - methylmalonyl-CoA mutase activity
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

643244

MMAA
Methylmalonic aciduria type A protein, mitochondrial

2

0

Small-scale

0.799

High

643219

MUTA
Methylmalonyl-CoA mutase, mitochondrial

1

1

Small-scale

0.734

High

643230

QOR
Quinone oxidoreductase

2

0

High-throughput

0.585

High

643246

GRPE2
GrpE protein homolog 2, mitochondrial

2

0

High-throughput

0.585

High

279648

CISY
Citrate synthase, mitochondrial

2

0

High-throughput

0.559

High

643221

KAD4
Adenylate kinase 4, mitochondrial

1

0

High-throughput

0.513

High

643234

ICT1
Large ribosomal subunit protein mL62

1

0

High-throughput

0.513

High

643238

ACSM5
Acyl-coenzyme A synthetase ACSM5, mitochondrial

1

0

High-throughput

0.513

High

643239

FAHD1
Oxaloacetate tautomerase FAHD1, mitochondrial

1

0

High-throughput

0.513

High

643245

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

643249

RT24
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.513

High

643256

DIC
Mitochondrial dicarboxylate carrier

1

0

High-throughput

0.513

High

643258

AMACR
Alpha-methylacyl-CoA racemase

1

0

High-throughput

0.513

High

643262

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

643224

HD
Huntingtin

1

0

High-throughput

0.493

High

643247

MCUR1
Mitochondrial calcium uniporter regulator 1

1

1

High-throughput

0.479

High

643252

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

1

High-throughput

0.479

High

411348

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

415991

CP1A1
Cytochrome P450 1A1

1

0

High-throughput

0.458

High

470848

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.458

High

536495

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

612866

EGR1
Early growth response protein 1

1

0

High-throughput

0.458

High

643223

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

643225

IF2M
Translation initiation factor IF-2, mitochondrial

1

0

High-throughput

0.458

High

643226

PSB2
Proteasome subunit beta type-2

1

0

High-throughput

0.458

High

643229

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

643232

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.458

High

643233

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.458

High

643235

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

643236

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.458

High

643237

OXLD1
Oxidoreductase-like domain-containing protein 1

1

0

High-throughput

0.458

High

643241

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

643243

BPHL
Serine hydrolase BPHL

1

0

High-throughput

0.458

High

643253

MTG2
Mitochondrial ribosome-associated GTPase 2

1

0

High-throughput

0.458

High

643254

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

643255

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

643257

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

643259

XPO7
Exportin-7

1

0

High-throughput

0.458

High

643220

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.426

High

643231

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.426

High

643251

TR61B
tRNA

1

0

High-throughput

0.426

High

643261

GAB2
GRB2-associated-binding protein 2

1

0

High-throughput

0.426

High

472272

CFAH
Complement factor H

1

0

High-throughput

0.279

Low

643240

T184A
Transmembrane protein 184A

1

0

High-throughput

0.279

Low

643260

KLF15
Krueppel-like factor 15

1

0

High-throughput

0.279

Low

105337

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

643250

T3HPD
Trans-3-hydroxy-L-proline dehydratase

1

0

High-throughput

0.249

Low

643222

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

643227

CTBP2
C-terminal-binding protein 2

1

0

High-throughput

0.249

Low

643228

PHS
Pterin-4-alpha-carbinolamine dehydratase

1

0

High-throughput

0.249

Low

643242

CTGE6
cTAGE family member 6

1

0

High-throughput

0.249

Low

643248

ARHGQ
Rho guanine nucleotide exchange factor 26

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025