Protein: AMACR
Alpha-methylacyl-CoA racemase (EC 5.1.99.4) (2-methylacyl-CoA racemase)

Gene: AMACR
Organism: Homo sapiens
Interactions: 67
UniProt ID: Q9UHK6

Gene Ontology (top 5):
GO:0005102 - signaling receptor binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005777 - peroxisome
GO:0005782 - peroxisomal matrix

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1106112

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

2

0

High-throughput

0.602

High

1206312

PSMG4
Proteasome assembly chaperone 4

2

0

High-throughput

0.602

High

1413182

PSMG3
Proteasome assembly chaperone 3

2

0

High-throughput

0.602

High

62010

GTPBA
GTP-binding protein 10

1

1

High-throughput

0.536

High

229172

GTPB6
Putative GTP-binding protein 6

1

2

High-throughput

0.536

High

554857

ODBA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

1

1

High-throughput

0.536

High

856421

IF2M
Translation initiation factor IF-2, mitochondrial

1

1

High-throughput

0.536

High

884722

SYHM
Histidine--tRNA ligase, mitochondrial

1

1

High-throughput

0.536

High

1138908

SYLM
Leucine--tRNA ligase, mitochondrial

1

1

High-throughput

0.536

High

1194770

ACSF3
Malonate--CoA ligase ACSF3, mitochondrial

1

1

High-throughput

0.536

High

1200289

FAKD1
FAST kinase domain-containing protein 1, mitochondrial

1

1

High-throughput

0.536

High

1210638

SYVM
Valine--tRNA ligase, mitochondrial

1

1

High-throughput

0.536

High

1381768

FAKD4
FAST kinase domain-containing protein 4

1

1

High-throughput

0.536

High

1385785

NSUN4
5-cytosine rRNA methyltransferase NSUN4

1

1

High-throughput

0.536

High

1386092

ACSF2
Medium-chain acyl-CoA ligase ACSF2, mitochondrial

1

1

High-throughput

0.536

High

1433749

MTG2
Mitochondrial ribosome-associated GTPase 2

1

1

High-throughput

0.536

High

1437481

RSAD1
Radical S-adenosyl methionine domain-containing protein 1, mitochondrial

1

1

High-throughput

0.536

High

1459992

SARDH
Sarcosine dehydrogenase, mitochondrial

1

1

High-throughput

0.536

High

1459995

COQ6
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial

1

1

High-throughput

0.536

High

1202081

HS905
Putative heat shock protein HSP 90-alpha A5

2

0

High-throughput

0.528

High

61673

VWA8
von Willebrand factor A domain-containing protein 8

1

0

High-throughput

0.513

High

66327

MET15
12S rRNA N(4)-cytidine methyltransferase METTL15

1

0

High-throughput

0.513

High

134406

RPOM
DNA-directed RNA polymerase, mitochondrial

1

0

High-throughput

0.513

High

166711

BCKD
Branched-chain alpha-ketoacid dehydrogenase kinase

1

0

High-throughput

0.513

High

177618

MRPP3
Mitochondrial ribonuclease P catalytic subunit

1

0

High-throughput

0.513

High

271112

PTCD1
Pentatricopeptide repeat-containing protein 1, mitochondrial

1

0

High-throughput

0.513

High

296168

GATB
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial

1

0

High-throughput

0.513

High

301996

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

0

High-throughput

0.513

High

322339

GLSK
Glutaminase kidney isoform, mitochondrial

1

0

High-throughput

0.513

High

333726

NDUAA
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial

1

0

High-throughput

0.513

High

425972

PCCB
Propionyl-CoA carboxylase beta chain, mitochondrial

1

0

High-throughput

0.513

High

533045

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.513

High

547219

PYC
Pyruvate carboxylase, mitochondrial

1

0

High-throughput

0.513

High

643258

MUTA
Methylmalonyl-CoA mutase, mitochondrial

1

0

High-throughput

0.513

High

653646

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.513

High

662811

CPT2
Carnitine O-palmitoyltransferase 2, mitochondrial

1

0

High-throughput

0.513

High

894498

PPOX
Protoporphyrinogen oxidase

1

0

High-throughput

0.513

High

926135

DPOG1
DNA polymerase subunit gamma-1

1

0

High-throughput

0.513

High

932959

P5CS
Delta-1-pyrroline-5-carboxylate synthase

1

0

High-throughput

0.513

High

960602

PSME3
Proteasome activator complex subunit 3

1

0

High-throughput

0.513

High

1052967

FOLC
Folylpolyglutamate synthase, mitochondrial

1

0

High-throughput

0.513

High

1061366

CP24A
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

1

0

High-throughput

0.513

High

1093499

COASY
Bifunctional coenzyme A synthase

1

0

High-throughput

0.513

High

1205748

SYEM
Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial

1

0

High-throughput

0.513

High

1207177

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

1244601

SYDM
Aspartate--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

1247915

C1TM
Monofunctional C1-tetrahydrofolate synthase, mitochondrial

1

0

High-throughput

0.513

High

1325704

GUF1
Translation factor GUF1, mitochondrial

1

0

High-throughput

0.513

High

1387079

COQ8B
Atypical kinase COQ8B, mitochondrial

1

0

High-throughput

0.513

High

1403210

CK5P1
Mitochondrial tRNA methylthiotransferase CDK5RAP1

1

0

High-throughput

0.513

High

1410057

RNZ2
Zinc phosphodiesterase ELAC protein 2

1

0

High-throughput

0.513

High

1416037

SYTM
Threonine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

1417450

HDHD5
Haloacid dehalogenase-like hydrolase domain-containing 5

1

0

High-throughput

0.513

High

1428937

PIP30
PSME3-interacting protein

1

0

High-throughput

0.513

High

1448463

D39U1
Epimerase family protein SDR39U1

1

0

High-throughput

0.513

High

1450541

TMLH
Trimethyllysine dioxygenase, mitochondrial

1

0

High-throughput

0.513

High

1451683

RM16
Large ribosomal subunit protein uL16m

1

0

High-throughput

0.513

High

1459993

MTO1
5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial

1

0

High-throughput

0.513

High

1459994

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

1459996

CIA30
Complex I intermediate-associated protein 30, mitochondrial

1

0

High-throughput

0.513

High

1459997

PUS1
Pseudouridylate synthase 1 homolog

1

0

High-throughput

0.513

High

1114579

CUL3
Cullin-3

1

0

High-throughput

0.458

High

58962

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

0

High-throughput

0.426

High

1199740

KLH22
Kelch-like protein 22

1

0

High-throughput

0.426

High

896328

PEX5
Peroxisomal targeting signal 1 receptor

1

0

Small-scale

0.391

High

1357598

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.249

Low

1335435

SPX3
Sugar phosphate exchanger 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025