Protein: ALG2
Alpha-1,3/1,6-mannosyltransferase ALG2 (EC 2.4.1.132) (EC 2.4.1.257) (Asparagine-linked glycosylation protein 2 homolog) (GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase) (GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase) (GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase)

Gene: ALG2
Organism: Homo sapiens
Interactions: 56
UniProt ID: Q9H553

Gene Ontology (top 5):
GO:0000033 - alpha-1,3-mannosyltransferase activity
GO:0004378 - GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity
GO:0005789 - endoplasmic reticulum membrane
GO:0006486 - protein glycosylation
GO:0006487 - protein N-linked glycosylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1357005

PDC6I
Programmed cell death 6-interacting protein

5

1

Small-scale

0.712

High

720043

HMOX2
Heme oxygenase 2

3

0

High-throughput

0.638

High

1434477

ALG2
Alpha-1,3/1,6-mannosyltransferase ALG2

1

6

Small-scale

0.621

High

628021

ANXA7
Annexin A7

2

1

Small-scale

0.611

High

899715

ANX11
Annexin A11

2

1

Small-scale

0.611

High

218776

TGON2
Trans-Golgi network integral membrane protein 2

3

1

High-throughput

0.609

High

1434483

VSIG4
V-set and immunoglobulin domain-containing protein 4

2

0

High-throughput

0.576

High

859696

RL21
Large ribosomal subunit protein eL21

2

0

High-throughput

0.559

High

1322580

SHSA5
Protein shisa-5

1

0

Small-scale

0.537

High

358802

LDHA
L-lactate dehydrogenase A chain

1

1

High-throughput

0.536

High

63034

POTEF
POTE ankyrin domain family member F

1

0

High-throughput

0.513

High

486618

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.513

High

565709

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

0

High-throughput

0.513

High

1434479

TECR
Very-long-chain enoyl-CoA reductase

1

0

High-throughput

0.513

High

1432900

PTN23
Tyrosine-protein phosphatase non-receptor type 23

1

1

Small-scale

0.504

High

821772

CD79B
B-cell antigen receptor complex-associated protein beta chain

1

1

High-throughput

0.489

High

1429283

S22A4
Solute carrier family 22 member 4

1

1

High-throughput

0.489

High

721170

SORCN
Sorcin

1

0

Small-scale

0.480

High

242928

PRKN
E3 ubiquitin-protein ligase parkin

1

6

High-throughput

0.479

High

323911

SC31A
Protein transport protein Sec31A

1

1

Small-scale

0.479

High

333204

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

1

High-throughput

0.445

High

564369

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.445

High

638520

FPR1
fMet-Leu-Phe receptor

1

1

High-throughput

0.445

High

1125300

FAK2
Protein-tyrosine kinase 2-beta

1

1

Small-scale

0.437

High

1255540

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

774622

BASI
Basigin

1

0

High-throughput

0.426

High

983575

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

0

High-throughput

0.426

High

262306

SCN2B
Sodium channel regulatory subunit beta-2

1

1

High-throughput

0.407

High

479080

CEL3A
Chymotrypsin-like elastase family member 3A

1

1

High-throughput

0.407

High

628463

KLK2
Kallikrein-2

1

1

High-throughput

0.407

High

941842

ARL4C
ADP-ribosylation factor-like protein 4C

1

1

High-throughput

0.407

High

1432113

KLK15
Kallikrein-15

1

1

High-throughput

0.407

High

1434482

CLC11
C-type lectin domain family 11 member A

1

1

High-throughput

0.407

High

1407465

TS101
Tumor susceptibility gene 101 protein

3

0

Small-scale

0.345

High

1233485

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.279

Low

843984

HD
Huntingtin

1

0

High-throughput

0.268

Low

927548

ATX1
Ataxin-1

1

0

High-throughput

0.268

Low

331325

KI20A
Kinesin-like protein KIF20A

1

0

High-throughput

0.249

Low

589682

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

1217427

OBSCN
Obscurin

1

0

High-throughput

0.249

Low

1312603

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

High-throughput

0.249

Low

1338223

VP37A
Vacuolar protein sorting-associated protein 37A

1

0

Small-scale

0.249

Low

1412980

CNPY3
Protein canopy homolog 3

1

0

Small-scale

0.249

Low

1433884

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1434478

PLS3
Phospholipid scramblase 3

1

0

Small-scale

0.249

Low

1434480

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

1434481

VPS28
Vacuolar protein sorting-associated protein 28 homolog

1

0

Small-scale

0.249

Low

64908

RCCD1
RCC1 domain-containing protein 1

1

0

High-throughput

0.232

Low

317371

ACL6B
Actin-like protein 6B

1

0

High-throughput

0.232

Low

388669

C1QA
Complement C1q subcomponent subunit A

1

0

High-throughput

0.232

Low

424306

INHA
Inhibin alpha chain

1

0

High-throughput

0.232

Low

457701

TBB5
Tubulin beta chain

1

0

High-throughput

0.232

Low

669364

ACKR3
Atypical chemokine receptor 3

1

0

High-throughput

0.232

Low

1199039

KLH12
Kelch-like protein 12

1

0

High-throughput

0.232

Low

1420110

CHIA
Acidic mammalian chitinase

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025