Protein: COPT1
High affinity copper uptake protein 1 (Copper transporter 1) (hCTR1) (Solute carrier family 31 member 1) [Cleaved into: Truncated CTR1 form]

Gene: COPT1, SLC31A1
Organism: Homo sapiens
Interactions: 182
UniProt ID: O15431

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0005375 - copper ion transmembrane transporter activity
GO:0005507 - copper ion binding
GO:0005886 - plasma membrane
GO:0006825 - copper ion transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

179127

COPT1
High affinity copper uptake protein 1

3

7

Small-scale

0.672

High

178308

STX7
Syntaxin-7

3

0

High-throughput

0.638

High

179142

ERBB3
Receptor tyrosine-protein kinase erbB-3

3

0

High-throughput

0.638

High

179149

CD70
CD70 antigen

2

0

High-throughput

0.602

High

179197

NR3L1
Natural cytotoxicity triggering receptor 3 ligand 1

2

0

High-throughput

0.602

High

179215

TM11B
Transmembrane protease serine 11B

2

0

High-throughput

0.602

High

179172

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

1

Small-scale

0.561

High

179128

COPT2
Protein SLC31A2

1

7

High-throughput

0.536

High

179138

APBA3
Amyloid-beta A4 precursor protein-binding family A member 3

1

2

High-throughput

0.536

High

179144

AVR2A
Activin receptor type-2A

1

2

High-throughput

0.536

High

179145

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

3

High-throughput

0.536

High

179150

BMR1A
Bone morphogenetic protein receptor type-1A

1

2

High-throughput

0.536

High

179171

DLG1
Disks large homolog 1

1

1

High-throughput

0.536

High

179175

MTMR1
Myotubularin-related protein 1

1

2

High-throughput

0.536

High

179176

AVR2B
Activin receptor type-2B

1

2

High-throughput

0.536

High

179179

DIP2A
Disco-interacting protein 2 homolog A

1

2

High-throughput

0.536

High

179192

MPP7
MAGUK p55 subfamily member 7

1

1

High-throughput

0.536

High

179205

RHDF2
Inactive rhomboid protein 2

1

1

High-throughput

0.536

High

179222

ARL17
ADP-ribosylation factor-like protein 17

1

1

High-throughput

0.536

High

179233

P4K2B
Phosphatidylinositol 4-kinase type 2-beta

1

1

High-throughput

0.536

High

179250

OSMR
Oncostatin-M-specific receptor subunit beta

1

1

High-throughput

0.536

High

179251

APBA2
Amyloid-beta A4 precursor protein-binding family A member 2

1

2

High-throughput

0.536

High

179253

P4K2A
Phosphatidylinositol 4-kinase type 2-alpha

1

1

High-throughput

0.536

High

179268

LIN7C
Protein lin-7 homolog C

1

2

High-throughput

0.536

High

179281

S12A4
Solute carrier family 12 member 4

1

2

High-throughput

0.536

High

179282

SC5A6
Sodium-dependent multivitamin transporter

1

2

High-throughput

0.536

High

179283

NISCH
Nischarin

1

1

High-throughput

0.536

High

179287

MRCKB
Serine/threonine-protein kinase MRCK beta

1

1

High-throughput

0.536

High

179289

S12A7
Solute carrier family 12 member 7

1

2

High-throughput

0.536

High

157791

T4S5
Transmembrane 4 L6 family member 5

1

0

High-throughput

0.513

High

160261

AURKA
Aurora kinase A

1

0

High-throughput

0.513

High

179129

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

0

High-throughput

0.513

High

179131

ADCY6
Adenylate cyclase type 6

1

0

High-throughput

0.513

High

179132

LTOR5
Ragulator complex protein LAMTOR5

1

0

High-throughput

0.513

High

179134

ACSL4
Long-chain-fatty-acid--CoA ligase 4

1

0

High-throughput

0.513

High

179135

NMT2
Glycylpeptide N-tetradecanoyltransferase 2

1

0

High-throughput

0.513

High

179141

RAB4A
Ras-related protein Rab-4A

1

0

High-throughput

0.513

High

179143

PTPRD
Receptor-type tyrosine-protein phosphatase delta

1

0

High-throughput

0.513

High

179147

UFO
Tyrosine-protein kinase receptor UFO

1

0

High-throughput

0.513

High

179148

ARRB2
Beta-arrestin-2

1

0

High-throughput

0.513

High

179151

WNT5A
Protein Wnt-5a

1

0

High-throughput

0.513

High

179152

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

0

High-throughput

0.513

High

179154

GRK6
G protein-coupled receptor kinase 6

1

0

High-throughput

0.513

High

179159

RAB13
Ras-related protein Rab-13

1

0

High-throughput

0.513

High

179163

ARF5
ADP-ribosylation factor 5

1

0

High-throughput

0.513

High

179164

AT2C1
Calcium-transporting ATPase type 2C member 1

1

0

High-throughput

0.513

High

179165

PYRD
Dihydroorotate dehydrogenase

1

0

High-throughput

0.513

High

179167

DDR1
Epithelial discoidin domain-containing receptor 1

1

0

High-throughput

0.513

High

179173

PLD1
Phospholipase D1

1

0

High-throughput

0.513

High

179174

DGKZ
Diacylglycerol kinase zeta

1

0

High-throughput

0.513

High

179180

SHB
SH2 domain-containing adapter protein B

1

0

High-throughput

0.513

High

179188

PKHG4
Puratrophin-1

1

0

High-throughput

0.513

High

179191

SNP47
Synaptosomal-associated protein 47

1

0

High-throughput

0.513

High

179195

DAB2P
Disabled homolog 2-interacting protein

1

0

High-throughput

0.513

High

179201

C2D1A
Coiled-coil and C2 domain-containing protein 1A

1

0

High-throughput

0.513

High

179207

DUSTY
Dual serine/threonine and tyrosine protein kinase

1

0

High-throughput

0.513

High

179226

ARG39
Rho guanine nucleotide exchange factor 39

1

0

High-throughput

0.513

High

179234

CERK1
Ceramide kinase

1

0

High-throughput

0.513

High

179239

TR19L
Tumor necrosis factor receptor superfamily member 19L

1

0

High-throughput

0.513

High

179241

NGBR
Dehydrodolichyl diphosphate synthase complex subunit NUS1

1

0

High-throughput

0.513

High

179255

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

0

High-throughput

0.513

High

179258

CE295
Centrosomal protein of 295 kDa

1

0

High-throughput

0.513

High

179259

ADT4
ADP/ATP translocase 4

1

0

High-throughput

0.513

High

179265

CD320
CD320 antigen

1

0

High-throughput

0.513

High

179266

IL1AP
Interleukin-1 receptor accessory protein

1

0

High-throughput

0.513

High

179271

FMN2
Formin-2

1

0

High-throughput

0.513

High

179278

NB5R1
NADH-cytochrome b5 reductase 1

1

0

High-throughput

0.513

High

179288

SNX9
Sorting nexin-9

1

0

High-throughput

0.513

High

179292

KC1G3
Casein kinase I isoform gamma-3

1

0

High-throughput

0.513

High

179293

ZNT1
Proton-coupled zinc antiporter SLC30A1

1

0

High-throughput

0.513

High

179294

WASF2
Actin-binding protein WASF2

1

0

High-throughput

0.513

High

129145

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

2

High-throughput

0.489

High

179137

MTMR5
Myotubularin-related protein 5

1

2

High-throughput

0.489

High

179140

PPAL
Lysosomal acid phosphatase

1

1

High-throughput

0.489

High

179170

SIA4C
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4

1

1

High-throughput

0.489

High

179182

SIA4B
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2

1

1

High-throughput

0.489

High

179185

AR13B
ADP-ribosylation factor-like protein 13B

1

1

High-throughput

0.489

High

179194

MRCKA
Serine/threonine-protein kinase MRCK alpha

1

1

High-throughput

0.489

High

179203

FXL19
F-box/LRR-repeat protein 19

1

1

High-throughput

0.489

High

179204

KLD10
Kelch domain-containing protein 10

1

1

High-throughput

0.489

High

179208

UBP30
Ubiquitin carboxyl-terminal hydrolase 30

1

1

High-throughput

0.489

High

179210

POGZ
Pogo transposable element with ZNF domain

1

1

High-throughput

0.489

High

179219

MTMRD
Myotubularin-related protein 13

1

2

High-throughput

0.489

High

179236

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

1

2

High-throughput

0.489

High

179237

ZN592
Zinc finger protein 592

1

1

High-throughput

0.489

High

179243

DDX11
ATP-dependent DNA helicase DDX11

1

2

High-throughput

0.489

High

179244

FACR2
Fatty acyl-CoA reductase 2

1

2

High-throughput

0.489

High

179245

MARK4
MAP/microtubule affinity-regulating kinase 4

1

1

High-throughput

0.489

High

179252

KLDC3
Kelch domain-containing protein 3

1

1

High-throughput

0.489

High

179254

FANCJ
Fanconi anemia group J protein

1

2

High-throughput

0.489

High

179267

SNRK
SNF-related serine/threonine-protein kinase

1

1

High-throughput

0.489

High

179272

RTEL1
Regulator of telomere elongation helicase 1

1

2

High-throughput

0.489

High

179274

DIP2B
Disco-interacting protein 2 homolog B

1

2

High-throughput

0.489

High

179290

SAR1B
Small COPII coat GTPase SAR1B

1

1

High-throughput

0.489

High

179139

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

126979

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

0

High-throughput

0.458

High

150283

CCS
Copper chaperone for superoxide dismutase

1

0

Small-scale

0.458

High

179158

CDK7
Cyclin-dependent kinase 7

1

0

High-throughput

0.458

High

179162

CD81
CD81 antigen

1

0

High-throughput

0.426

High

121055

LEG8
Galectin-8

3

0

High-throughput

0.347

High

179206

PXDC2
Plexin domain-containing protein 2

2

0

High-throughput

0.328

High

179248

NED4L
E3 ubiquitin-protein ligase NEDD4-like

2

0

Small-scale

0.305

High

61954

CB072
Uncharacterized protein C2orf72

1

0

High-throughput

0.279

Low

70629

MYO9A
Unconventional myosin-IXa

1

0

High-throughput

0.279

Low

161588

GAK
Cyclin-G-associated kinase

1

0

High-throughput

0.279

Low

167183

MRPP3
Mitochondrial ribonuclease P catalytic subunit

1

0

High-throughput

0.279

Low

175589

INP4B
Inositol polyphosphate 4-phosphatase type II

1

0

High-throughput

0.279

Low

179130

SERA
D-3-phosphoglycerate dehydrogenase

1

0

High-throughput

0.279

Low

179133

XRCC3
DNA repair protein XRCC3

1

0

High-throughput

0.279

Low

179136

B3GA3
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3

1

0

High-throughput

0.279

Low

179146

DPOD1
DNA polymerase delta catalytic subunit

1

0

High-throughput

0.279

Low

179153

MTOR
Serine/threonine-protein kinase mTOR

1

0

High-throughput

0.279

Low

179155

TPC10
Trafficking protein particle complex subunit 10

1

0

High-throughput

0.279

Low

179156

PRI1
DNA primase small subunit

1

0

High-throughput

0.279

Low

179157

PRI2
DNA primase large subunit

1

0

High-throughput

0.279

Low

179160

LIMK2
LIM domain kinase 2

1

0

High-throughput

0.279

Low

179161

PMS1
PMS1 protein homolog 1

1

0

High-throughput

0.279

Low

179166

FOXM1
Forkhead box protein M1

1

0

High-throughput

0.279

Low

179168

ABD18
Protein ABHD18

1

0

High-throughput

0.279

Low

179169

DYH14
Dynein axonemal heavy chain 14

1

0

High-throughput

0.279

Low

179177

NUCG
Endonuclease G, mitochondrial

1

0

High-throughput

0.279

Low

179178

ZN268
Zinc finger protein 268

1

0

High-throughput

0.279

Low

179181

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

0

High-throughput

0.279

Low

179183

CP51A
Lanosterol 14-alpha demethylase

1

0

High-throughput

0.279

Low

179184

HSDL1
Inactive hydroxysteroid dehydrogenase-like protein 1

1

0

High-throughput

0.279

Low

179186

TTC31
Tetratricopeptide repeat protein 31

1

0

High-throughput

0.279

Low

179187

ESCO2
N-acetyltransferase ESCO2

1

0

High-throughput

0.279

Low

179189

ZRAB3
DNA annealing helicase and endonuclease ZRANB3

1

0

High-throughput

0.279

Low

179190

WDR44
WD repeat-containing protein 44

1

0

High-throughput

0.279

Low

179193

M3K21
Mitogen-activated protein kinase kinase kinase 21

1

0

High-throughput

0.279

Low

179196

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.279

Low

179198

ACD10
Acyl-CoA dehydrogenase family member 10

1

0

High-throughput

0.279

Low

179199

LIN54
Protein lin-54 homolog

1

0

High-throughput

0.279

Low

179200

RETST
All-trans-retinol 13,14-reductase

1

0

High-throughput

0.279

Low

179202

MEAK7
MTOR-associated protein MEAK7

1

0

High-throughput

0.279

Low

179209

MCM10
Protein MCM10 homolog

1

0

High-throughput

0.279

Low

179211

UBE3D
E3 ubiquitin-protein ligase E3D

1

0

High-throughput

0.279

Low

179212

PKHH3
Pleckstrin homology domain-containing family H member 3

1

0

High-throughput

0.279

Low

179213

CTU1
Cytoplasmic tRNA 2-thiolation protein 1

1

0

High-throughput

0.279

Low

179214

TPC6B
Trafficking protein particle complex subunit 6B

1

0

High-throughput

0.279

Low

179216

ADCK1
AarF domain-containing protein kinase 1

1

0

High-throughput

0.279

Low

179217

ZN598
E3 ubiquitin-protein ligase ZNF598

1

0

High-throughput

0.279

Low

179218

T200A
Transmembrane protein 200A

1

0

High-throughput

0.279

Low

179220

NIT1
Deaminated glutathione amidase

1

0

High-throughput

0.279

Low

179221

CEP57
Centrosomal protein of 57 kDa

1

0

High-throughput

0.279

Low

179223

DEN6A
Protein DENND6A

1

0

High-throughput

0.279

Low

179224

PUSL1
tRNA pseudouridine synthase-like 1

1

0

High-throughput

0.279

Low

179225

T151A
Transmembrane protein 151A

1

0

High-throughput

0.279

Low

179227

DTWD1
tRNA-uridine aminocarboxypropyltransferase 1

1

0

High-throughput

0.279

Low

179228

CISD2
CDGSH iron-sulfur domain-containing protein 2

1

0

High-throughput

0.279

Low

179229

SMG8
Nonsense-mediated mRNA decay factor SMG8

1

0

High-throughput

0.279

Low

179230

CBPC5
Cytosolic carboxypeptidase-like protein 5

1

0

High-throughput

0.279

Low

179231

UBP32
Ubiquitin carboxyl-terminal hydrolase 32

1

0

High-throughput

0.279

Low

179232

NEIL3
Endonuclease 8-like 3

1

0

High-throughput

0.279

Low

179235

MZB1
Marginal zone B- and B1-cell-specific protein

1

0

High-throughput

0.279

Low

179238

MARC2
Mitochondrial amidoxime reducing component 2

1

0

High-throughput

0.279

Low

179240

NMD3
60S ribosomal export protein NMD3

1

0

High-throughput

0.279

Low

179242

THA11
THAP domain-containing protein 11

1

0

High-throughput

0.279

Low

179246

GUCD1
Protein GUCD1

1

0

High-throughput

0.279

Low

179247

AGAP3
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3

1

0

High-throughput

0.279

Low

179249

TPPC9
Trafficking protein particle complex subunit 9

1

0

High-throughput

0.279

Low

179256

HELZ2
3'-5' exoribonuclease HELZ2

1

0

High-throughput

0.279

Low

179257

DPH1
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1

1

0

High-throughput

0.279

Low

179260

NSUN3
tRNA

1

0

High-throughput

0.279

Low

179261

PEAK1
Inactive tyrosine-protein kinase PEAK1

1

0

High-throughput

0.279

Low

179262

WDR76
WD repeat-containing protein 76

1

0

High-throughput

0.279

Low

179263

L2HDH
L-2-hydroxyglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

179264

ELP3
Elongator complex protein 3

1

0

High-throughput

0.279

Low

179269

MITOS
Mitochondrial potassium channel ATP-binding subunit

1

0

High-throughput

0.279

Low

179270

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.279

Low

179273

DTL
Denticleless protein homolog

1

0

High-throughput

0.279

Low

179275

FXL17
F-box/LRR-repeat protein 17

1

0

High-throughput

0.279

Low

179279

MRM2
rRNA methyltransferase 2, mitochondrial

1

0

High-throughput

0.279

Low

179280

TASOR
Protein TASOR

1

0

High-throughput

0.279

Low

179284

HBS1L
HBS1-like protein

1

0

High-throughput

0.279

Low

179286

AMMR1
Nuclear protein AMMECR1

1

0

High-throughput

0.279

Low

179291

TAF6L
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L

1

0

High-throughput

0.279

Low

179295

S23IP
SEC23-interacting protein

1

0

High-throughput

0.279

Low

179277

AAKG2
5'-AMP-activated protein kinase subunit gamma-2

1

0

Small-scale

0.261

Low

179285

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

0

Small-scale

0.261

Low

179276

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024