Protein: MORC3
MORC family CW-type zinc finger protein 3 (Nuclear matrix protein 2) (Zinc finger CW-type coiled-coil domain protein 3)

Gene: MORC3
Organism: Homo sapiens
Interactions: 76
UniProt ID: Q14149

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0003677 - DNA binding
GO:0003723 - RNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

991524

DYL1
Dynein light chain 1, cytoplasmic

6

1

High-throughput

0.739

High

1121644

DYL2
Dynein light chain 2, cytoplasmic

4

1

High-throughput

0.691

High

998306

H31
Histone H3.1

3

4

High-throughput

0.640

High

1121631

MORC3
MORC family CW-type zinc finger protein 3

1

5

Small-scale

0.618

High

507956

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

1

High-throughput

0.602

High

714108

PML
Protein PML

2

1

Small-scale

0.584

High

1121653

RN216
E3 ubiquitin-protein ligase RNF216

2

0

High-throughput

0.580

High

413814

P53
Cellular tumor antigen p53

2

1

High-throughput

0.571

High

966301

1433G
14-3-3 protein gamma

1

4

High-throughput

0.554

High

931514

RD23A
UV excision repair protein RAD23 homolog A

2

0

Small-scale

0.547

High

142550

IMA3
Importin subunit alpha-3

1

1

High-throughput

0.541

High

238817

KALRN
Kalirin

1

2

High-throughput

0.541

High

297601

PIAS1
E3 SUMO-protein ligase PIAS1

1

1

High-throughput

0.541

High

939187

SUMO3
Small ubiquitin-related modifier 3

1

1

High-throughput

0.541

High

993564

UBC9
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.541

High

1040290

DYST
Dystonin

1

1

High-throughput

0.541

High

1050992

FAK1
Focal adhesion kinase 1

1

2

High-throughput

0.541

High

1121636

RN123
E3 ubiquitin-protein ligase RNF123

1

1

High-throughput

0.541

High

1121646

RANB9
Ran-binding protein 9

1

1

High-throughput

0.541

High

1121649

SPTN4
Spectrin beta chain, non-erythrocytic 4

1

1

High-throughput

0.541

High

1121658

ZMYM5
Zinc finger MYM-type protein 5

1

1

High-throughput

0.541

High

1121661

PIAS3
E3 SUMO-protein ligase PIAS3

1

1

High-throughput

0.541

High

1065188

SSRP1
FACT complex subunit SSRP1

1

2

High-throughput

0.536

High

1121641

SYNE2
Nesprin-2

1

2

High-throughput

0.536

High

971511

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.530

High

721156

SORCN
Sorcin

1

0

High-throughput

0.518

High

1121642

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.518

High

1121643

ARK2N
Protein ARK2N

1

0

High-throughput

0.518

High

1121659

MKLN1
Muskelin

1

0

High-throughput

0.518

High

1121660

KIF3A
Kinesin-like protein KIF3A

1

0

High-throughput

0.518

High

843555

HD
Huntingtin

1

0

High-throughput

0.513

High

1121635

DEP1A
DEP domain-containing protein 1A

1

0

High-throughput

0.513

High

1121645

TRIB1
Tribbles homolog 1

1

0

High-throughput

0.513

High

1121648

GDF15
Growth/differentiation factor 15

1

0

High-throughput

0.513

High

1049279

1433F
14-3-3 protein eta

1

4

High-throughput

0.506

High

964272

SUMO2
Small ubiquitin-related modifier 2

1

1

High-throughput

0.501

High

1042861

ERCC6
DNA excision repair protein ERCC-6

1

1

High-throughput

0.501

High

1034155

ROR1
Inactive tyrosine-protein kinase transmembrane receptor ROR1

1

1

Small-scale

0.489

High

910892

IMA1
Importin subunit alpha-1

1

1

High-throughput

0.481

High

241651

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

487298

PARP1
Poly [ADP-ribose] polymerase 1

1

3

High-throughput

0.479

High

520033

ANDR
Androgen receptor

1

5

High-throughput

0.479

High

588669

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

695430

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

729823

1433B
14-3-3 protein beta/alpha

1

4

High-throughput

0.479

High

768163

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

879076

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.479

High

980758

H2B1C
Histone H2B type 1-C/E/F/G/I

1

1

High-throughput

0.479

High

990210

1433Z
14-3-3 protein zeta/delta

1

4

High-throughput

0.479

High

1016846

H33
Histone H3.3

1

4

High-throughput

0.479

High

1113078

CUL3
Cullin-3

1

1

High-throughput

0.479

High

1121632

SUZ12
Polycomb protein SUZ12

1

1

High-throughput

0.479

High

1121637

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

1121647

TBX5
T-box transcription factor TBX5

1

2

High-throughput

0.479

High

1121655

ZMYM2
Zinc finger MYM-type protein 2

1

1

High-throughput

0.479

High

1121657

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

620362

NUCL
Nucleolin

1

0

High-throughput

0.458

High

799099

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.458

High

1004553

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

1088837

TP53B
TP53-binding protein 1

1

0

High-throughput

0.458

High

1121633

KS6A1
Ribosomal protein S6 kinase alpha-1

1

0

High-throughput

0.458

High

1121656

DAXX
Death domain-associated protein 6

1

0

Small-scale

0.458

High

1121639

RDH10
Retinol dehydrogenase 10

1

1

High-throughput

0.437

High

1121650

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

374596

RASH
GTPase HRas

1

0

High-throughput

0.426

High

95823

E5RK48
Retinol dehydrogenase 10

1

1

High-throughput

0.407

High

1121634

CF141
Uncharacterized protein C6orf141

2

0

High-throughput

0.328

High

333332

SNAPN
SNARE-associated protein Snapin

1

0

High-throughput

0.282

High

1121651

RETR1
Reticulophagy regulator 1

1

0

High-throughput

0.282

High

1116859

MOGS
Mannosyl-oligosaccharide glucosidase

1

0

High-throughput

0.279

Low

1118429

SNTB1
Beta-1-syntrophin

1

0

High-throughput

0.279

Low

1121638

FAM9C
Protein FAM9C

1

0

High-throughput

0.279

Low

1121640

DOCK8
Dedicator of cytokinesis protein 8

1

0

High-throughput

0.279

Low

1121654

CRIPT
Cysteine-rich PDZ-binding protein

1

0

High-throughput

0.279

Low

1121652

DLRB1
Dynein light chain roadblock-type 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025