Protein: MF2L2
Probable guanine nucleotide exchange factor MCF2L2 (Dbs-related Rho family guanine nucleotide exchange factor) (MCF2-transforming sequence-like protein 2)

Gene: MF2L2, MCF2L2
Organism: Homo sapiens
Interactions: 41
UniProt ID: Q86YR7

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1025382

CDK6
Cyclin-dependent kinase 6

2

3

High-throughput

0.628

High

1295385

HIC2
Hypermethylated in cancer 2 protein

2

1

High-throughput

0.574

High

1099146

SRSF5
Serine/arginine-rich splicing factor 5

2

4

High-throughput

0.571

High

1295398

ANFY1
Rabankyrin-5

2

12

High-throughput

0.571

High

128270

PSD12
26S proteasome non-ATPase regulatory subunit 12

2

0

High-throughput

0.547

High

1209096

EXOS6
Exosome complex component MTR3

2

0

High-throughput

0.547

High

1295382

NU205
Nuclear pore complex protein Nup205

2

0

High-throughput

0.547

High

1108873

OLIG2
Oligodendrocyte transcription factor 2

1

2

High-throughput

0.541

High

1295395

BIRC6
Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6

1

5

High-throughput

0.536

High

350610

TXD12
Thioredoxin domain-containing protein 12

2

3

High-throughput

0.521

High

959612

MAX
Protein max

2

11

High-throughput

0.521

High

1295380

MGAP
MAX gene-associated protein

2

3

High-throughput

0.521

High

1295390

SF3B5
Splicing factor 3B subunit 5

2

1

High-throughput

0.521

High

1295391

RT26
Small ribosomal subunit protein mS26

2

1

High-throughput

0.521

High

1295384

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

3

Small-scale

0.515

High

331112

KI20A
Kinesin-like protein KIF20A

1

13

High-throughput

0.479

High

451021

LDHB
L-lactate dehydrogenase B chain

1

1

High-throughput

0.479

High

724772

METK2
S-adenosylmethionine synthase isoform type-2

1

1

High-throughput

0.479

High

973062

RS29
Small ribosomal subunit protein uS14

1

2

High-throughput

0.479

High

973759

RUXE
Small nuclear ribonucleoprotein E

1

1

High-throughput

0.479

High

1119964

CIRBP
Cold-inducible RNA-binding protein

1

2

High-throughput

0.479

High

1217149

RIF1
Telomere-associated protein RIF1

1

9

High-throughput

0.479

High

1295389

RANB9
Ran-binding protein 9

1

1

High-throughput

0.479

High

698846

CALX
Calnexin

1

1

High-throughput

0.470

High

992246

SKP1
S-phase kinase-associated protein 1

1

0

High-throughput

0.458

High

1131758

LBR
Delta(14)-sterol reductase LBR

1

0

High-throughput

0.458

High

1295386

SPTCS
Spatacsin

1

2

Small-scale

0.457

High

1295397

DISC1
Disrupted in schizophrenia 1 protein

1

10

High-throughput

0.457

High

895597

SERPH
Serpin H1

1

7

High-throughput

0.437

High

1295381

TM263
Transmembrane protein 263

1

3

High-throughput

0.437

High

1295393

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

1

9

High-throughput

0.437

High

1295400

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

3

High-throughput

0.437

High

1295388

IPO9
Importin-9

1

0

High-throughput

0.426

High

1295387

MEG10
Multiple epidermal growth factor-like domains protein 10

1

2

Small-scale

0.417

High

372485

MYC
Myc proto-oncogene protein

1

14

High-throughput

0.407

High

256324

RT14
Small ribosomal subunit protein uS14m

2

0

High-throughput

0.298

High

1295383

RT31
Small ribosomal subunit protein mS31

2

0

High-throughput

0.298

High

1295392

DPY30
Protein dpy-30 homolog

2

0

High-throughput

0.298

High

1295396

CHRC1
Chromatin accessibility complex protein 1

1

0

High-throughput

0.279

Low

1295394

SFXN1
Sideroflexin-1

1

0

High-throughput

0.249

Low

1295399

STML2
Stomatin-like protein 2, mitochondrial

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025