Protein: DPY30
Protein dpy-30 homolog (Dpy-30-like protein) (Dpy-30L)

Gene: DPY30
Organism: Homo sapiens
Interactions: 184
UniProt ID: Q9C005

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005794 - Golgi apparatus
GO:0005802 - trans-Golgi network
GO:0016197 - endosomal transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1420458

DPY30
Protein dpy-30 homolog

7

1

Small-scale

0.969

High

1359112

DYDC1
DPY30 domain-containing protein 1

3

1

High-throughput

0.861

High

1394292

DYDC2
DPY30 domain-containing protein 2

2

1

High-throughput

0.783

High

1420472

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

21

6

Small-scale

0.768

High

965218

WDR5
WD repeat-containing protein 5

8

2

Small-scale

0.747

High

1145521

RBBP5
Retinoblastoma-binding protein 5

7

5

Small-scale

0.740

High

1420468

CXXC1
CXXC-type zinc finger protein 1

5

5

Small-scale

0.716

High

175924

SET1A
Histone-lysine N-methyltransferase SETD1A

5

7

Small-scale

0.709

High

1312688

BAP18
BPTF-associated chromatin complex component 1

4

0

Small-scale

0.665

High

1257124

PAXI1
PAX-interacting protein 1

3

3

Small-scale

0.657

High

1288073

RSPH3
Radial spoke head protein 3 homolog

2

0

High-throughput

0.655

High

1086813

BPTF
Nucleosome-remodeling factor subunit BPTF

3

3

Small-scale

0.651

High

194608

KDM6A
Lysine-specific demethylase 6A

3

2

Small-scale

0.650

High

1130598

NCOA6
Nuclear receptor coactivator 6

3

2

Small-scale

0.650

High

138306

PSDE
26S proteasome non-ATPase regulatory subunit 14

3

0

High-throughput

0.646

High

129401

MEN1
Menin

4

0

Small-scale

0.643

High

1005956

GTF2I
General transcription factor II-I

3

0

High-throughput

0.639

High

1041592

KMT2A
Histone-lysine N-methyltransferase 2A

3

7

Small-scale

0.633

High

1420492

BIG1
Brefeldin A-inhibited guanine nucleotide-exchange protein 1

2

1

Small-scale

0.619

High

243725

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

2

2

Small-scale

0.618

High

703372

SMCA1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1

2

2

Small-scale

0.618

High

1066478

RBBP4
Histone-binding protein RBBP4

2

1

Small-scale

0.618

High

1420480

KMT2B
Histone-lysine N-methyltransferase 2B

2

7

Small-scale

0.611

High

1420482

SET1B
Histone-lysine N-methyltransferase SETD1B

2

7

High-throughput

0.611

High

1413529

PAGR1
PAXIP1-associated glutamate-rich protein 1

3

0

Small-scale

0.606

High

66549

TSPY2
Testis-specific Y-encoded protein 2

2

2

High-throughput

0.606

High

1338272

KMT2C
Histone-lysine N-methyltransferase 2C

2

8

Small-scale

0.595

High

316976

MTA2
Metastasis-associated protein MTA2

2

3

Small-scale

0.594

High

905477

HCFC1
Host cell factor 1

2

1

Small-scale

0.594

High

373089

MYC
Myc proto-oncogene protein

2

1

High-throughput

0.584

High

520355

ANDR
Androgen receptor

2

2

High-throughput

0.584

High

610462

PRS6A
26S proteasome regulatory subunit 6A

2

0

High-throughput

0.580

High

1025634

CDK17
Cyclin-dependent kinase 17

2

0

High-throughput

0.580

High

1213146

BEND3
BEN domain-containing protein 3

2

0

High-throughput

0.580

High

1228210

CR3L3
Cyclic AMP-responsive element-binding protein 3-like protein 3

2

0

High-throughput

0.580

High

1336664

ICA1L
Islet cell autoantigen 1-like protein

2

0

High-throughput

0.580

High

1420466

GPTC2
G patch domain-containing protein 2

2

0

High-throughput

0.580

High

1420490

MOFA1
MORF4 family-associated protein 1

2

0

High-throughput

0.580

High

161511

KMT2D
Histone-lysine N-methyltransferase 2D

2

7

Small-scale

0.571

High

396890

ESR1
Estrogen receptor

2

2

High-throughput

0.571

High

1279148

RHG22
Rho GTPase-activating protein 22

2

1

High-throughput

0.571

High

980282

H4
Histone H4

2

0

High-throughput

0.559

High

386199

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

2

0

High-throughput

0.547

High

625604

CSK22
Casein kinase II subunit alpha'

1

1

High-throughput

0.536

High

998001

CSK21
Casein kinase II subunit alpha

1

1

High-throughput

0.536

High

1029747

FOXK2
Forkhead box protein K2

1

1

High-throughput

0.536

High

1163192

H2B2E
Histone H2B type 2-E

1

2

High-throughput

0.536

High

1250037

WDR82
WD repeat-containing protein 82

1

5

Small-scale

0.536

High

1420487

KDM2A
Lysine-specific demethylase 2A

1

1

High-throughput

0.536

High

1420491

BIG2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2

1

1

High-throughput

0.536

High

511004

TSPYA
Testis-specific Y-encoded protein 10

1

2

High-throughput

0.529

High

1324074

RHG24
Rho GTPase-activating protein 24

2

1

High-throughput

0.521

High

215183

PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3

1

0

High-throughput

0.518

High

1372297

H2B1H
Histone H2B type 1-H

1

2

High-throughput

0.515

High

229076

AKAP8
A-kinase anchor protein 8

1

0

Small-scale

0.513

High

342312

BRD1
Bromodomain-containing protein 1

1

0

High-throughput

0.513

High

502118

H2AZ
Histone H2A.Z

1

0

High-throughput

0.513

High

542202

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

571634

IRF2
Interferon regulatory factor 2

1

0

High-throughput

0.513

High

584142

FOSL2
Fos-related antigen 2

1

0

High-throughput

0.513

High

601847

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.513

High

650947

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

0

High-throughput

0.513

High

729439

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

0

High-throughput

0.513

High

846465

MATR3
Matrin-3

1

0

High-throughput

0.513

High

882564

ARRB1
Beta-arrestin-1

1

0

High-throughput

0.513

High

885888

KC1E
Casein kinase I isoform epsilon

1

0

High-throughput

0.513

High

1065415

SSRP1
FACT complex subunit SSRP1

1

0

High-throughput

0.513

High

1115989

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.513

High

1250653

BCOR
BCL-6 corepressor

1

0

Small-scale

0.513

High

1401495

UIMC1
BRCA1-A complex subunit RAP80

1

0

High-throughput

0.513

High

1420465

FANCI
Fanconi anemia group I protein

1

0

High-throughput

0.513

High

1420473

DAXX
Death domain-associated protein 6

1

0

High-throughput

0.513

High

733220

OTX1
Homeobox protein OTX1

1

1

High-throughput

0.508

High

573885

CCNB1
G2/mitotic-specific cyclin-B1

1

0

High-throughput

0.493

High

1420477

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

High-throughput

0.493

High

1060569

KLC1
Kinesin light chain 1

1

1

High-throughput

0.489

High

1030940

TSPY1
Testis-specific Y-encoded protein 1

1

2

High-throughput

0.481

High

508575

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

1395182

ZN462
Zinc finger protein 462

1

0

Small-scale

0.479

High

1420483

SATB2
DNA-binding protein SATB2

1

0

Small-scale

0.479

High

143237

NFIB
Nuclear factor 1 B-type

1

2

High-throughput

0.479

High

223557

ZN207
BUB3-interacting and GLEBS motif-containing protein ZNF207

1

2

High-throughput

0.479

High

260419

BRD4
Bromodomain-containing protein 4

1

2

High-throughput

0.479

High

332040

KAT7
Histone acetyltransferase KAT7

1

1

High-throughput

0.479

High

352239

MBD3
Methyl-CpG-binding domain protein 3

1

1

High-throughput

0.479

High

404396

GCR
Glucocorticoid receptor

1

2

High-throughput

0.479

High

406615

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

474265

NFIC
Nuclear factor 1 C-type

1

4

High-throughput

0.479

High

607083

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

664807

CCND1
G1/S-specific cyclin-D1

1

1

High-throughput

0.479

High

754976

H2B1B
Histone H2B type 1-B

1

2

High-throughput

0.479

High

907571

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

1

High-throughput

0.479

High

937893

FOXA1
Hepatocyte nuclear factor 3-alpha

1

1

High-throughput

0.479

High

998778

H31
Histone H3.1

1

2

High-throughput

0.479

High

1017190

H33
Histone H3.3

1

2

High-throughput

0.479

High

1087994

NFIA
Nuclear factor 1 A-type

1

3

High-throughput

0.479

High

1088549

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

2

High-throughput

0.479

High

1089008

TP53B
TP53-binding protein 1

1

1

High-throughput

0.479

High

1102644

MTA1
Metastasis-associated protein MTA1

1

3

High-throughput

0.479

High

1129734

MDC1
Mediator of DNA damage checkpoint protein 1

1

3

High-throughput

0.479

High

1287012

UBP37
Ubiquitin carboxyl-terminal hydrolase 37

1

1

Small-scale

0.479

High

1295298

P66A
Transcriptional repressor p66-alpha

1

1

High-throughput

0.479

High

1314690

SRRM1
Serine/arginine repetitive matrix protein 1

1

3

High-throughput

0.479

High

1361002

P66B
Transcriptional repressor p66-beta

1

1

High-throughput

0.479

High

1368605

KAT6A
Histone acetyltransferase KAT6A

1

5

High-throughput

0.479

High

1380146

FBXW7
F-box/WD repeat-containing protein 7

1

1

Small-scale

0.479

High

1387737

MBD6
Methyl-CpG-binding domain protein 6

1

3

High-throughput

0.479

High

1398767

PWP2A
PWWP domain-containing protein 2A

1

1

High-throughput

0.479

High

1413337

MTA3
Metastasis-associated protein MTA3

1

3

High-throughput

0.479

High

1420460

WDR76
WD repeat-containing protein 76

1

3

High-throughput

0.479

High

1420462

NANOG
Homeobox protein NANOG

1

1

High-throughput

0.479

High

1420469

MBD5
Methyl-CpG-binding domain protein 5

1

1

High-throughput

0.479

High

1420470

RERE
Arginine-glutamic acid dipeptide repeats protein

1

4

High-throughput

0.479

High

1420471

MBD2
Methyl-CpG-binding domain protein 2

1

1

High-throughput

0.479

High

1420478

YETS2
YEATS domain-containing protein 2

1

3

High-throughput

0.479

High

1420481

ING4
Inhibitor of growth protein 4

1

2

High-throughput

0.479

High

1420489

HCFC2
Host cell factor 2

1

1

High-throughput

0.479

High

155349

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

0

High-throughput

0.458

High

168318

HAT1
Histone acetyltransferase type B catalytic subunit

1

0

High-throughput

0.458

High

181936

SMAD9
Mothers against decapentaplegic homolog 9

1

0

Small-scale

0.458

High

223311

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

282302

SAP30
Histone deacetylase complex subunit SAP30

1

0

High-throughput

0.458

High

283140

PSIP1
PC4 and SFRS1-interacting protein

1

0

High-throughput

0.458

High

285720

BAF
Barrier-to-autointegration factor

1

0

Small-scale

0.458

High

326022

UBR5
E3 ubiquitin-protein ligase UBR5

1

0

High-throughput

0.458

High

343044

HERC2
E3 ubiquitin-protein ligase HERC2

1

0

High-throughput

0.458

High

519558

MYBB
Myb-related protein B

1

0

High-throughput

0.458

High

786831

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

0

High-throughput

0.458

High

799460

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.458

High

879444

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

895036

EMD
Emerin

1

0

Small-scale

0.458

High

913808

ZN131
Zinc finger protein 131

1

0

High-throughput

0.458

High

971045

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

1033774

PO5F1
POU domain, class 5, transcription factor 1

1

0

High-throughput

0.458

High

1114227

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1137509

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.458

High

1138611

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1208640

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

0

High-throughput

0.458

High

1216626

LIN9
Protein lin-9 homolog

1

0

High-throughput

0.458

High

1229673

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1276102

KANL1
KAT8 regulatory NSL complex subunit 1

1

0

High-throughput

0.458

High

1338355

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

1352734

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1364580

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

1390156

MCRS1
Microspherule protein 1

1

0

High-throughput

0.458

High

1392567

LIN37
Protein lin-37 homolog

1

0

High-throughput

0.458

High

1394239

BOD1
Biorientation of chromosomes in cell division protein 1

1

0

High-throughput

0.458

High

1396122

Z512B
Zinc finger protein 512B

1

0

High-throughput

0.458

High

1407413

EPAS1
Endothelial PAS domain-containing protein 1

1

0

Small-scale

0.458

High

1420459

BC11A
BCL11 transcription factor A

1

0

High-throughput

0.458

High

1420461

KANL2
KAT8 regulatory NSL complex subunit 2

1

0

High-throughput

0.458

High

1420463

EAF6
Chromatin modification-related protein MEAF6

1

0

High-throughput

0.458

High

1420467

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1420474

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1420475

HMGX4
HMG domain-containing protein 4

1

1

Small-scale

0.457

High

1206536

PRC2B
Protein PRRC2B

1

4

High-throughput

0.439

High

1420479

HECD1
E3 ubiquitin-protein ligase HECTD1

1

1

High-throughput

0.437

High

185998

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

Small-scale

0.426

High

1356478

TB22A
TBC1 domain family member 22A

1

0

Small-scale

0.426

High

1420485

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.426

High

1162035

H31T
Histone H3.1t

1

2

High-throughput

0.408

High

878554

PAXI
Paxillin

3

0

High-throughput

0.340

High

1278711

CFA91
Cilia- and flagella-associated protein 91

2

0

High-throughput

0.316

High

1288705

AKA28
A-kinase anchor protein 14

2

0

High-throughput

0.316

High

1351357

BCAS4
Breast carcinoma-amplified sequence 4

2

0

High-throughput

0.316

High

1385337

F136A
Protein FAM136A

2

0

High-throughput

0.316

High

1395636

ANCHR
Abscission/NoCut checkpoint regulator

2

0

High-throughput

0.316

High

1397939

KAD8
Adenylate kinase 8

2

0

High-throughput

0.316

High

699088

CALX
Calnexin

2

0

High-throughput

0.298

High

1295392

MF2L2
Probable guanine nucleotide exchange factor MCF2L2

2

0

High-throughput

0.298

High

839082

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

0

High-throughput

0.279

Low

1310026

FXRD2
FAD-dependent oxidoreductase domain-containing protein 2

1

0

High-throughput

0.279

Low

1420476

CHRD1
Cysteine and histidine-rich domain-containing protein 1

1

0

High-throughput

0.279

Low

1420486

E41L3
Band 4.1-like protein 3

1

0

High-throughput

0.279

Low

1420488

PCDBF
Protocadherin beta-15

1

0

High-throughput

0.279

Low

270118

TMCC2
Transmembrane and coiled-coil domains protein 2

1

0

High-throughput

0.251

Low

157820

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

294293

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

1412975

CNPY3
Protein canopy homolog 3

1

0

Small-scale

0.249

Low

1420464

ARHG4
Rho guanine nucleotide exchange factor 4

1

0

High-throughput

0.249

Low

1279426

AB1IP
Amyloid beta A4 precursor protein-binding family B member 1-interacting protein

1

0

High-throughput

0.238

Low

1420484

CHM2B
Charged multivesicular body protein 2b

1

0

High-throughput

0.238

Low

1335710

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025