Protein: GNPTA
N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (EC 2.7.8.17) (GlcNAc-1-phosphotransferase subunits alpha/beta) (Stealth protein GNPTAB) (UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta) [Cleaved into: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta]

Gene: GNPTA, GNPTAB
Organism: Homo sapiens
Interactions: 66
UniProt ID: Q3T906

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0003976 - UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity
GO:0005509 - calcium ion binding
GO:0005794 - Golgi apparatus
GO:0007040 - lysosome organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

351861

IGSF6
Immunoglobulin superfamily member 6

2

0

High-throughput

0.679

High

1188014

SGCZ
Zeta-sarcoglycan

3

1

High-throughput

0.656

High

229186

B3GT2
Beta-1,3-galactosyltransferase 2

3

0

High-throughput

0.638

High

1188021

PICK1
PRKCA-binding protein

3

0

High-throughput

0.638

High

1188008

PXYP1
2-phosphoxylose phosphatase 1

2

0

High-throughput

0.602

High

1188024

GNPTG
N-acetylglucosamine-1-phosphotransferase subunit gamma

2

0

Small-scale

0.585

High

1187995

GNPTA
N-acetylglucosamine-1-phosphotransferase subunits alpha/beta

1

0

Small-scale

0.546

High

703612

MK01
Mitogen-activated protein kinase 1

1

0

High-throughput

0.518

High

1037068

OC90
Otoconin-90

1

0

High-throughput

0.513

High

1188006

SPP2B
Signal peptide peptidase-like 2B

1

0

High-throughput

0.513

High

1188018

CHST8
Carbohydrate sulfotransferase 8

1

0

High-throughput

0.513

High

1188019

NDST4
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4

1

0

High-throughput

0.513

High

1188026

DSE
Dermatan-sulfate epimerase

1

0

High-throughput

0.513

High

422230

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

218252

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

668615

APC
Adenomatous polyposis coli protein

1

0

High-throughput

0.458

High

1113251

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1188016

S29A3
Equilibrative nucleoside transporter 3

1

0

High-throughput

0.458

High

170785

CLGN
Calmegin

1

0

High-throughput

0.426

High

1188017

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.426

High

538761

GTR2
Solute carrier family 2, facilitated glucose transporter member 2

1

1

High-throughput

0.407

High

1033928

SC6A3
Sodium-dependent dopamine transporter

1

1

High-throughput

0.407

High

1066069

Q08AT0
SGCZ protein

1

1

High-throughput

0.407

High

1139439

S39AE
Metal cation symporter ZIP14

1

1

High-throughput

0.407

High

1188000

S39A4
Zinc transporter ZIP4

1

1

High-throughput

0.407

High

1188001

GTR7
Solute carrier family 2, facilitated glucose transporter member 7

1

1

High-throughput

0.407

High

1188015

S4A5
Electrogenic sodium bicarbonate cotransporter 4

1

1

High-throughput

0.407

High

1188023

S6A13
Sodium- and chloride-dependent GABA transporter 2

1

1

High-throughput

0.407

High

1188027

S4A7
Sodium bicarbonate cotransporter 3

1

1

High-throughput

0.407

High

1188002

RETR3
Reticulophagy regulator 3

4

0

High-throughput

0.360

High

1039106

RASF7
Ras association domain-containing protein 7

3

0

High-throughput

0.347

High

1188007

ZPLD1
Zona pellucida-like domain-containing protein 1

2

0

High-throughput

0.328

High

1188022

DISC1
Disrupted in schizophrenia 1 protein

2

0

High-throughput

0.307

High

585042

ZN250
Zinc finger protein 250

1

0

High-throughput

0.299

High

680894

PSA1
Proteasome subunit alpha type-1

1

0

High-throughput

0.299

High

1188003

F90A1
Protein FAM90A1

1

0

High-throughput

0.299

High

1188009

AEN
Apoptosis-enhancing nuclease

1

0

High-throughput

0.299

High

1188012

STALP
AMSH-like protease

1

0

High-throughput

0.299

High

249145

DSCAM
Cell adhesion molecule DSCAM

1

0

High-throughput

0.282

High

351899

S1PR4
Sphingosine 1-phosphate receptor 4

1

0

High-throughput

0.279

Low

480812

LEG1
Galectin-1

1

0

High-throughput

0.279

Low

640390

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

0

High-throughput

0.279

Low

946356

FAM3B
Protein FAM3B

1

0

High-throughput

0.279

Low

948532

APC15
Anaphase-promoting complex subunit 15

1

0

High-throughput

0.279

Low

1187997

CV042
Uncharacterized protein C22orf42

1

0

High-throughput

0.279

Low

1187998

PRR27
Proline-rich protein 27

1

0

High-throughput

0.279

Low

1188005

THOC2
THO complex subunit 2

1

0

High-throughput

0.279

Low

1188011

T106A
Transmembrane protein 106A

1

0

High-throughput

0.279

Low

1188025

FBX2
F-box only protein 2

1

0

High-throughput

0.279

Low

134761

SAP18
Histone deacetylase complex subunit SAP18

1

0

High-throughput

0.269

Low

1027495

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

0

High-throughput

0.269

Low

276837

VATG1
V-type proton ATPase subunit G 1

1

0

High-throughput

0.249

Low

377093

PDYN
Proenkephalin-B

1

0

High-throughput

0.249

Low

729887

1433B
14-3-3 protein beta/alpha

1

0

High-throughput

0.249

Low

872384

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.249

Low

967450

RS7
Small ribosomal subunit protein eS7

1

0

High-throughput

0.249

Low

1095262

REST
RE1-silencing transcription factor

1

0

High-throughput

0.249

Low

947006

DSCR9
Down syndrome critical region protein 9

1

0

High-throughput

0.238

Low

722474

CTR1
High affinity cationic amino acid transporter 1

1

0

High-throughput

0.232

Low

1187996

KLH22
Kelch-like protein 22

1

0

High-throughput

0.232

Low

1187999

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.232

Low

1188004

S35F3
Solute carrier family 35 member F3

1

0

High-throughput

0.232

Low

1188010

S22AH
Solute carrier family 22 member 17

1

0

High-throughput

0.232

Low

1188013

S47A1
Multidrug and toxin extrusion protein 1

1

0

High-throughput

0.232

Low

1188020

GPC5C
G-protein coupled receptor family C group 5 member C

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025