Protein: SQS1
Protein SQS1 (Squelch of splicing suppression protein 1)

Gene: SQS1
Organism: Saccharomyces cerevisiae S288C
Interactions: 77
UniProt ID: P53866

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0003676 - nucleic acid binding
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

917443

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

12

0

Small-scale

0.935

High

924132

HAS1
ATP-dependent RNA helicase HAS1

1

2

High-throughput

0.752

High

632712

DBP4
ATP-dependent RNA helicase HCA4

1

2

High-throughput

0.698

High

779146

DHR2
Probable ATP-dependent RNA helicase DHR2

1

1

High-throughput

0.698

High

864491

MTR4
ATP-dependent RNA helicase DOB1

1

1

Small-scale

0.618

High

677510

KRR1
KRR1 small subunit processome component

2

0

High-throughput

0.610

High

666513

DBP2
ATP-dependent RNA helicase DBP2

1

0

High-throughput

0.586

High

792175

GBLP
Small ribosomal subunit protein RACK1

2

0

High-throughput

0.585

High

747034

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

1

1

High-throughput

0.582

High

514763

RS18A
Small ribosomal subunit protein uS13A

2

0

High-throughput

0.559

High

674757

RS2
Small ribosomal subunit protein uS5

2

0

Small-scale

0.559

High

918795

UTP22
U3 small nucleolar RNA-associated protein 22

1

0

High-throughput

0.558

High

524759

HSP71
Heat shock protein SSA1

2

1

High-throughput

0.552

High

924134

SP382
Pre-mRNA-splicing factor SPP382

2

0

Small-scale

0.551

High

782086

RL1D1
Ribosome biogenesis protein UTP30

1

0

High-throughput

0.518

High

798282

ENP1
Essential nuclear protein 1

1

0

High-throughput

0.518

High

825546

UTP25
U3 small nucleolar RNA-associated protein 25

1

0

High-throughput

0.518

High

918604

SLX9
Ribosome biogenesis protein SLX9

1

0

High-throughput

0.518

High

919592

NOP19
Nucleolar protein 19

1

0

High-throughput

0.518

High

919749

PXR1
Protein PXR1

1

0

High-throughput

0.518

High

924122

SQS1
Protein SQS1

1

0

High-throughput

0.518

High

924127

UTP6
U3 small nucleolar RNA-associated protein 6

1

0

High-throughput

0.518

High

924133

SGD1
Suppressor of glycerol defect protein 1

1

0

High-throughput

0.518

High

924138

SAS10
Something about silencing protein 10

1

0

High-throughput

0.518

High

924140

RRP36
rRNA biogenesis protein RRP36

1

0

High-throughput

0.518

High

924142

NOP14
Nucleolar complex protein 14

1

0

High-throughput

0.518

High

545805

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.513

High

924129

IMA1
Importin subunit alpha

1

0

High-throughput

0.513

High

735531

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

0

High-throughput

0.480

High

149888

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.479

High

410264

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

435264

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

436092

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

436480

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.458

High

442042

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

512574

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

513142

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.458

High

513898

RS11B
Small ribosomal subunit protein uS17B

1

0

High-throughput

0.458

High

677951

YCQ6
Uncharacterized protein YCR016W

1

0

High-throughput

0.458

High

678250

BUD23
18S rRNA

1

0

High-throughput

0.458

High

689586

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

707826

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

741044

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

0

High-throughput

0.458

High

747505

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.458

High

753508

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.458

High

778464

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

802306

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

815352

PAC2
Protein PAC2

1

0

High-throughput

0.458

High

874452

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

923174

NOG2
Nucleolar GTP-binding protein 2

1

0

High-throughput

0.458

High

924123

NOP13
Nucleolar protein 13

1

0

High-throughput

0.458

High

924124

NOP3
Serine/arginine

1

0

High-throughput

0.458

High

924125

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

924128

XRN2
5'-3' exoribonuclease 2

1

0

High-throughput

0.458

High

924130

NOG1
Nucleolar GTP-binding protein 1

1

0

High-throughput

0.458

High

924131

TMA23
Protein TMA23

1

0

Small-scale

0.458

High

924135

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

924139

YRA1
RNA annealing protein YRA1

1

0

High-throughput

0.458

High

924141

RRP12
Ribosomal RNA-processing protein 12

1

0

High-throughput

0.458

High

527350

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

742117

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

671675

SCJ1
DnaJ-related protein SCJ1

1

0

High-throughput

0.426

High

813829

MBO1
Gamma tubulin complex adapter SPC72

1

0

High-throughput

0.269

Low

383827

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

433770

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

455192

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

503170

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

504343

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

513736

RL2A
Large ribosomal subunit protein uL2A

1

0

High-throughput

0.249

Low

795134

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

807836

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.249

Low

812539

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

918416

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

924136

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

924137

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

924126

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025