Protein: UTP25
U3 small nucleolar RNA-associated protein 25 (U3 snoRNA-associated protein 25) (U three protein 25)

Gene: UTP25
Organism: Saccharomyces cerevisiae S288C
Interactions: 92
UniProt ID: P40498

Gene Ontology (top 5):
GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0019843 - rRNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

825534

MPP10
U3 small nucleolar RNA-associated protein MPP10

5

1

Small-scale

0.729

High

825575

SAS10
Something about silencing protein 10

5

1

Small-scale

0.729

High

825561

UTP21
U3 small nucleolar RNA-associated protein 21

3

2

Small-scale

0.663

High

825545

ESF2
Pre-rRNA-processing protein ESF2

2

1

High-throughput

0.614

High

825550

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

2

1

High-throughput

0.614

High

798234

ENP1
Essential nuclear protein 1

3

0

High-throughput

0.613

High

825541

UTP22
U3 small nucleolar RNA-associated protein 22

2

0

High-throughput

0.610

High

818309

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

2

0

High-throughput

0.588

High

823340

UTP18
U3 small nucleolar RNA-associated protein 18

2

0

Small-scale

0.585

High

825542

UTP8
U3 small nucleolar RNA-associated protein 8

2

0

Small-scale

0.585

High

825566

RRP9
Ribosomal RNA-processing protein 9

2

0

Small-scale

0.585

High

677433

KRR1
KRR1 small subunit processome component

2

0

High-throughput

0.559

High

825557

UTP14
U3 small nucleolar RNA-associated protein 14

2

0

High-throughput

0.559

High

825567

NOC4
Nucleolar complex protein 4

2

0

High-throughput

0.559

High

779131

DHR2
Probable ATP-dependent RNA helicase DHR2

1

0

High-throughput

0.558

High

825578

RRP36
rRNA biogenesis protein RRP36

1

0

High-throughput

0.558

High

818945

SSB2
Ribosome-associated molecular chaperone SSB2

2

1

High-throughput

0.552

High

524177

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.536

High

545145

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.536

High

704611

SBA1
Co-chaperone protein SBA1

1

1

Small-scale

0.527

High

825540

SLX9
Ribosome biogenesis protein SLX9

1

0

High-throughput

0.518

High

825546

SQS1
Protein SQS1

1

0

High-throughput

0.518

High

656496

KC11
Casein kinase I homolog 1

1

1

High-throughput

0.501

High

656798

KC12
Casein kinase I homolog 2

1

1

High-throughput

0.501

High

825535

JHD2
Histone demethylase JHD2

1

0

High-throughput

0.493

High

748854

SWE1
Mitosis inhibitor protein kinase SWE1

1

0

High-throughput

0.480

High

808636

AURK
Aurora kinase

1

0

High-throughput

0.480

High

825553

SKY1
Serine/threonine-protein kinase SKY1

1

0

High-throughput

0.480

High

632686

DBP4
ATP-dependent RNA helicase HCA4

1

3

High-throughput

0.479

High

678402

PWP2
Periodic tryptophan protein 2

1

1

High-throughput

0.479

High

825530

UTP10
U3 small nucleolar RNA-associated protein 10

1

1

High-throughput

0.479

High

825547

NAT10
RNA cytidine acetyltransferase

1

1

High-throughput

0.479

High

825552

UTP17
NET1-associated nuclear protein 1

1

3

High-throughput

0.479

High

825554

UTP5
U3 small nucleolar RNA-associated protein 5

1

1

High-throughput

0.479

High

825560

UTP13
U3 small nucleolar RNA-associated protein 13

1

2

High-throughput

0.479

High

825562

SGD1
Suppressor of glycerol defect protein 1

1

1

High-throughput

0.479

High

825568

BFR2
Protein BFR2

1

1

High-throughput

0.479

High

825570

UTP4
U3 small nucleolar RNA-associated protein 4

1

1

High-throughput

0.479

High

825576

UTP12
U3 small nucleolar RNA-associated protein 12

1

2

High-throughput

0.479

High

825577

NOP56
Nucleolar protein 56

1

2

High-throughput

0.479

High

825579

NOP58
Nucleolar protein 58

1

2

High-throughput

0.479

High

825580

RRP12
Ribosomal RNA-processing protein 12

1

1

High-throughput

0.479

High

513048

RS8A
Small ribosomal subunit protein eS8A

1

0

Small-scale

0.458

High

670803

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

673188

RRP7
Ribosomal RNA-processing protein 7

1

0

High-throughput

0.458

High

707305

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

735012

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

754293

DCA13
Protein SOF1

1

0

High-throughput

0.458

High

758378

UTP11
U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.458

High

763576

UTP20
U3 small nucleolar RNA-associated protein 20

1

0

High-throughput

0.458

High

782073

RL1D1
Ribosome biogenesis protein UTP30

1

0

High-throughput

0.458

High

806530

UTP9
U3 small nucleolar RNA-associated protein 9

1

0

High-throughput

0.458

High

817580

UTP7
U3 small nucleolar RNA-associated protein 7

1

0

High-throughput

0.458

High

825054

RRT14
Regulator of rDNA transcription protein 14

1

0

High-throughput

0.458

High

825528

FAF1
Protein FAF1

1

0

High-throughput

0.458

High

825529

DIM1
Dimethyladenosine transferase

1

0

High-throughput

0.458

High

825532

ROK1
ATP-dependent RNA helicase ROK1

1

0

High-throughput

0.458

High

825533

MTR4
ATP-dependent RNA helicase DOB1

1

0

High-throughput

0.458

High

825537

NOL10
Ribosome biogenesis protein ENP2

1

0

High-throughput

0.458

High

825538

SAP4
SIT4-associating protein SAP4

1

0

High-throughput

0.458

High

825544

NOP19
Nucleolar protein 19

1

0

Small-scale

0.458

High

825549

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

825551

UTP6
U3 small nucleolar RNA-associated protein 6

1

0

High-throughput

0.458

High

825555

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.458

High

825556

UTP15
U3 small nucleolar RNA-associated protein 15

1

0

High-throughput

0.458

High

825558

RRP5
rRNA biogenesis protein RRP5

1

0

High-throughput

0.458

High

825559

FCF1
rRNA-processing protein FCF1

1

0

High-throughput

0.458

High

825564

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

0

High-throughput

0.458

High

825565

ESF1
Pre-rRNA-processing protein ESF1

1

0

High-throughput

0.458

High

825571

RCL1
rRNA processing protein RCL1

1

0

High-throughput

0.458

High

825572

UTP16
U3 small nucleolar RNA-associated protein 16

1

0

High-throughput

0.458

High

825573

BMS1
Ribosome biogenesis protein BMS1

1

0

High-throughput

0.458

High

825574

FCF2
rRNA-processing protein FCF2

1

0

High-throughput

0.458

High

825581

NOP14
Nucleolar complex protein 14

1

0

High-throughput

0.458

High

793161

AKL1
Serine/threonine-protein kinase AKL1

1

2

High-throughput

0.457

High

526879

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

727089

HS104
Heat shock protein 104

1

1

High-throughput

0.445

High

741724

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

792829

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.438

High

825548

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.438

High

739389

ZUO1
Zuotin

1

0

High-throughput

0.426

High

804217

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

825563

FKBP4
FK506-binding protein 4

1

0

High-throughput

0.426

High

752346

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.407

High

825569

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

1

High-throughput

0.407

High

825531

TOS3
Serine/threonine-protein kinase TOS3

1

0

High-throughput

0.261

Low

825536

ENT3
Epsin-3

1

0

Small-scale

0.261

Low

825539

ATG1
Serine/threonine-protein kinase ATG1

1

0

High-throughput

0.261

Low

558758

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

624763

PMA2
Plasma membrane ATPase 2

1

0

High-throughput

0.249

Low

812374

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

825543

TPO2
Polyamine transporter 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025