Protein: ELOV4
Very long chain fatty acid elongase 4 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL4) (ELOVL fatty acid elongase 4) (ELOVL FA elongase 4) (Elongation of very long chain fatty acids protein 4) (Very long chain 3-ketoacyl-CoA synthase 4) (Very long chain 3-oxoacyl-CoA synthase 4)

Gene: ELOV4, ELOVL4
Organism: Homo sapiens
Interactions: 133
UniProt ID: Q9GZR5

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006633 - fatty acid biosynthetic process
GO:0006636 - unsaturated fatty acid biosynthetic process
GO:0008020 - G protein-coupled photoreceptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1428504

ELOV4
Very long chain fatty acid elongase 4

1

4

Small-scale

0.618

High

160329

GOSR2
Golgi SNAP receptor complex member 2

2

3

High-throughput

0.606

High

180041

BET1
BET1 homolog

2

9

High-throughput

0.606

High

280328

SC22B
Vesicle-trafficking protein SEC22b

2

3

High-throughput

0.606

High

333185

VAPB
Vesicle-associated membrane protein-associated protein B/C

2

4

High-throughput

0.606

High

483968

HMOX1
Heme oxygenase 1

2

5

High-throughput

0.606

High

611333

PTN1
Tyrosine-protein phosphatase non-receptor type 1

2

3

High-throughput

0.606

High

720036

HMOX2
Heme oxygenase 2

2

5

High-throughput

0.606

High

789957

FDFT
Squalene synthase

2

1

High-throughput

0.606

High

1005412

CP4F2
Cytochrome P450 4F2

2

1

High-throughput

0.606

High

1091979

SEC20
Vesicle transport protein SEC20

2

1

High-throughput

0.606

High

1125644

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

2

1

High-throughput

0.606

High

1198945

ORML2
ORM1-like protein 2

2

1

High-throughput

0.606

High

1272376

FA2H
Fatty acid 2-hydroxylase

2

5

High-throughput

0.606

High

1322835

ORML3
ORM1-like protein 3

2

1

High-throughput

0.606

High

1327049

VMA12
Vacuolar ATPase assembly protein VMA12

2

1

High-throughput

0.606

High

1329664

SERP2
Stress-associated endoplasmic reticulum protein 2

2

1

High-throughput

0.606

High

1359665

GIMA1
GTPase IMAP family member 1

2

1

High-throughput

0.606

High

1388800

YIPF6
Protein YIPF6

2

1

High-throughput

0.606

High

1394424

FXDC2
Fatty acid hydroxylase domain-containing protein 2

2

6

High-throughput

0.606

High

1394448

SC22A
Vesicle-trafficking protein SEC22a

2

3

High-throughput

0.606

High

1406180

PMYT1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

2

1

High-throughput

0.606

High

1428507

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

2

2

High-throughput

0.606

High

1428510

AT131
Endoplasmic reticulum transmembrane helix translocase

2

6

High-throughput

0.606

High

1428516

TECR
Very-long-chain enoyl-CoA reductase

2

5

High-throughput

0.606

High

1428525

UB2J1
Ubiquitin-conjugating enzyme E2 J1

2

5

High-throughput

0.606

High

325594

YIF1A
Protein YIF1A

2

0

High-throughput

0.580

High

360109

NB5R3
NADH-cytochrome b5 reductase 3

2

0

High-throughput

0.580

High

688414

PPLA
Phospholamban

2

0

High-throughput

0.580

High

1060222

B2CL1
Bcl-2-like protein 1

2

0

High-throughput

0.580

High

1092090

BNIP3
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

2

0

High-throughput

0.580

High

1309054

ZDH21
Palmitoyltransferase ZDHHC21

2

0

High-throughput

0.580

High

1328196

JAGN1
Protein jagunal homolog 1

2

0

High-throughput

0.580

High

1381084

TM203
Transmembrane protein 203

2

0

High-throughput

0.580

High

1428511

RAB18
Ras-related protein Rab-18

2

0

High-throughput

0.580

High

1428514

TREX1
Three-prime repair exonuclease 1

2

0

High-throughput

0.580

High

1428521

ERG28
Ergosterol biosynthetic protein 28 homolog

2

0

High-throughput

0.580

High

1428527

IR3IP
Immediate early response 3-interacting protein 1

2

0

High-throughput

0.580

High

722610

CTR1
High affinity cationic amino acid transporter 1

2

19

High-throughput

0.574

High

1242923

S39A4
Zinc transporter ZIP4

2

7

High-throughput

0.558

High

60605

TM218
Transmembrane protein 218

2

1

High-throughput

0.553

High

258668

G37L1
G-protein coupled receptor 37-like 1

2

2

High-throughput

0.553

High

278556

VAMP4
Vesicle-associated membrane protein 4

2

6

High-throughput

0.553

High

297317

SERF1
Small EDRK-rich factor 1

2

1

High-throughput

0.553

High

327439

ZFPL1
Zinc finger protein-like 1

2

3

High-throughput

0.553

High

328736

VAMP5
Vesicle-associated membrane protein 5

2

7

High-throughput

0.553

High

331484

APOL3
Apolipoprotein L3

2

1

High-throughput

0.553

High

390952

TRFE
Serotransferrin

2

1

High-throughput

0.553

High

602265

TMM11
Transmembrane protein 11, mitochondrial

2

1

High-throughput

0.553

High

662361

VAMP1
Vesicle-associated membrane protein 1

2

8

High-throughput

0.553

High

712125

CO4A5

2

1

High-throughput

0.553

High

1092818

MALL
MAL-like protein

2

2

High-throughput

0.553

High

1100715

STX3
Syntaxin-3

2

3

High-throughput

0.553

High

1154734

VAMP3
Vesicle-associated membrane protein 3

2

7

High-throughput

0.553

High

1208737

RTP2
Receptor-transporting protein 2

2

2

High-throughput

0.553

High

1292136

ANR46
Ankyrin repeat domain-containing protein 46

2

1

High-throughput

0.553

High

1310948

ZNT8
Proton-coupled zinc antiporter SLC30A8

2

7

High-throughput

0.553

High

1388181

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

2

1

High-throughput

0.553

High

1390244

GIMA5
GTPase IMAP family member 5

2

1

High-throughput

0.553

High

1391135

CKLF7
CKLF-like MARVEL transmembrane domain-containing protein 7

2

3

High-throughput

0.553

High

1398560

CKLF3
CKLF-like MARVEL transmembrane domain-containing protein 3

2

4

High-throughput

0.553

High

1406741

ZNT3
Probable proton-coupled zinc antiporter SLC30A3

2

7

High-throughput

0.553

High

1414032

TM243
Transmembrane protein 243

2

1

High-throughput

0.553

High

1428505

FXYD6
FXYD domain-containing ion transport regulator 6

2

1

High-throughput

0.553

High

1428506

TM222
Transmembrane protein 222

2

4

High-throughput

0.553

High

1428508

SYNG1
Synapse differentiation-inducing gene protein 1

2

2

High-throughput

0.553

High

1428517

NINJ2
Ninjurin-2

2

1

High-throughput

0.553

High

1428520

AGRE2
Adhesion G protein-coupled receptor E2

2

1

High-throughput

0.553

High

1428524

PLLP
Plasmolipin

2

4

High-throughput

0.553

High

1270847

SV2A
Synaptic vesicle glycoprotein 2A

1

7

High-throughput

0.536

High

1391500

BSCL2
Seipin

1

1

High-throughput

0.536

High

1392296

ZDH12
Palmitoyltransferase ZDHHC12

1

1

High-throughput

0.536

High

182764

GP182
G-protein coupled receptor 182

1

8

High-throughput

0.489

High

596776

DPEP1
Dipeptidase 1

1

1

High-throughput

0.489

High

867677

GPR12
G-protein coupled receptor 12

1

4

High-throughput

0.489

High

880199

PTH2R
Parathyroid hormone 2 receptor

1

6

High-throughput

0.489

High

907057

CCR6
C-C chemokine receptor type 6

1

3

High-throughput

0.489

High

1053065

VMAT2
Synaptic vesicular amine transporter

1

4

High-throughput

0.489

High

1329171

SC5A8
Sodium-coupled monocarboxylate transporter 1

1

1

High-throughput

0.489

High

1348635

S7A14
Solute carrier family 7 member 14

1

15

High-throughput

0.489

High

1428523

SC5A6
Sodium-dependent multivitamin transporter

1

1

High-throughput

0.489

High

1410669

APOL2
Apolipoprotein L2

1

1

High-throughput

0.481

High

1428522

STX8
Syntaxin-8

1

8

High-throughput

0.481

High

1428529

UBIA1
UbiA prenyltransferase domain-containing protein 1

1

1

High-throughput

0.481

High

1391289

CERS2
Ceramide synthase 2

1

8

Small-scale

0.479

High

1404191

SEC62
Translocation protein SEC62

1

2

High-throughput

0.479

High

48204

A0AVG3
t-SNARE domain containing 1

1

7

High-throughput

0.470

High

63697

A5PKU2
TUSC5 protein

1

1

High-throughput

0.470

High

162273

CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

1

0

High-throughput

0.460

High

1358711

SRALN
Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator ARLN

1

0

High-throughput

0.460

High

1415004

EMC6
ER membrane protein complex subunit 6

1

0

High-throughput

0.460

High

1428526

INSI2
Insulin-induced gene 2 protein

1

0

High-throughput

0.460

High

1428528

PEX16
Peroxisomal membrane protein PEX16

1

0

High-throughput

0.460

High

1312125

TARG1
Trafficking regulator of GLUT4 1

1

1

High-throughput

0.439

High

1398900

TSNA1
t-SNARE domain-containing protein 1

1

8

High-throughput

0.439

High

1428519

LPAR3
Lysophosphatidic acid receptor 3

1

5

High-throughput

0.439

High

1337944

ZNT7
Zinc transporter 7

1

7

High-throughput

0.407

High

332702

LYPD3
Ly6/PLAUR domain-containing protein 3

2

0

High-throughput

0.318

High

1294759

LYPD6
Ly6/PLAUR domain-containing protein 6

2

0

High-throughput

0.318

High

329661

LERL1
Leptin receptor overlapping transcript-like 1

2

0

High-throughput

0.316

High

339232

SFT2B
Vesicle transport protein SFT2B

2

0

High-throughput

0.316

High

388291

GLPA
Glycophorin-A

2

0

High-throughput

0.316

High

539493

ITAM
Integrin alpha-M

2

0

High-throughput

0.316

High

749274

CD70
CD70 antigen

2

0

High-throughput

0.316

High

894440

MMP14
Matrix metalloproteinase-14

2

0

High-throughput

0.316

High

949293

MYPR
Myelin proteolipid protein

2

0

High-throughput

0.316

High

1102451

BIK
Bcl-2-interacting killer

2

0

High-throughput

0.316

High

1124165

LY6D
Lymphocyte antigen 6D

2

0

High-throughput

0.316

High

1179779

TMM44
Transmembrane protein 44

2

0

High-throughput

0.316

High

1200108

UNC50
Protein unc-50 homolog

2

0

High-throughput

0.316

High

1203344

TM128
Transmembrane protein 128

2

0

High-throughput

0.316

High

1229452

TMM42
Transmembrane protein 42

2

0

High-throughput

0.316

High

1249532

SNORC
Protein SNORC

2

0

High-throughput

0.316

High

1322723

F177A
Protein FAM177A1

2

0

High-throughput

0.316

High

1340537

CLDN2
Claudin domain-containing protein 2

2

0

High-throughput

0.316

High

1340710

CC4L
C-C motif chemokine 4-like

2

0

High-throughput

0.316

High

1347196

LHPL5
LHFPL tetraspan subfamily member 5 protein

2

0

High-throughput

0.316

High

1349015

TM254
Transmembrane protein 254

2

0

High-throughput

0.316

High

1358616

BT2A2
Butyrophilin subfamily 2 member A2

2

0

High-throughput

0.316

High

1363559

FAM3C
Protein FAM3C

2

0

High-throughput

0.316

High

1393236

TMM19
Transmembrane protein 19

2

0

High-throughput

0.316

High

1428515

TM242
Transmembrane protein 242

2

0

High-throughput

0.316

High

1428518

CC167
Coiled-coil domain-containing protein 167

2

0

High-throughput

0.316

High

602835

AATC
Aspartate aminotransferase, cytoplasmic

1

0

High-throughput

0.279

Low

1428509

NCKX3
Sodium/potassium/calcium exchanger 3

1

0

High-throughput

0.279

Low

1100644

DHRS2
Dehydrogenase/reductase SDR family member 2, mitochondrial

1

0

High-throughput

0.269

Low

74192

SMIM1
Small integral membrane protein 1

1

0

High-throughput

0.251

Low

1135563

CLCA4
Calcium-activated chloride channel regulator 4

1

0

High-throughput

0.251

Low

1428512

SMCO4
Single-pass membrane and coiled-coil domain-containing protein 4

1

0

High-throughput

0.251

Low

1428513

C1GLT
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

1

0

High-throughput

0.251

Low

761097

GBRA3
Gamma-aminobutyric acid receptor subunit alpha-3

1

0

High-throughput

0.249

Low

256142

S19A2
Thiamine transporter 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025