Protein: VGFR3
Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)

Gene: VGFR3, FLT4
Organism: Homo sapiens
Interactions: 244
UniProt ID: P35916

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001934 - positive regulation of protein phosphorylation
GO:0001938 - positive regulation of endothelial cell proliferation
GO:0001944 - vasculature development
GO:0001945 - lymph vessel development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

666022

SHC1
SHC-transforming protein 1

3

20

Small-scale

0.876

High

729237

VGFR2
Vascular endothelial growth factor receptor 2

3

17

Small-scale

0.827

High

217378

VEGFD
Vascular endothelial growth factor D

2

20

Small-scale

0.778

High

729289

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

2

5

High-throughput

0.778

High

729247

VEGFC
Vascular endothelial growth factor C

2

20

Small-scale

0.776

High

729258

GRB2
Growth factor receptor-bound protein 2

2

20

Small-scale

0.768

High

719673

RADI
Radixin

1

20

High-throughput

0.691

High

121120

LEG8
Galectin-8

3

6

High-throughput

0.667

High

729241

PE2R3
Prostaglandin E2 receptor EP3 subtype

3

2

High-throughput

0.667

High

382329

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

9

High-throughput

0.646

High

729273

PTK7
Inactive tyrosine-protein kinase 7

1

20

High-throughput

0.646

High

380094

MAS
Proto-oncogene Mas

2

2

High-throughput

0.628

High

729246

NPY2R
Neuropeptide Y receptor type 2

2

2

High-throughput

0.628

High

729394

PCDGD
Protocadherin gamma-B1

2

3

High-throughput

0.628

High

383654

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

Small-scale

0.621

High

118700

AIP
AH receptor-interacting protein

1

5

High-throughput

0.618

High

129225

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

20

High-throughput

0.618

High

414788

CDK1
Cyclin-dependent kinase 1

1

8

High-throughput

0.618

High

557624

NCK1
SH2/SH3 adapter protein NCK1

1

20

High-throughput

0.618

High

573600

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

20

High-throughput

0.618

High

640055

MOES
Moesin

1

20

High-throughput

0.618

High

655241

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

20

High-throughput

0.618

High

665160

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.618

High

729266

NOTC2
Neurogenic locus notch homolog protein 2

1

16

High-throughput

0.618

High

729307

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

1

3

High-throughput

0.618

High

729310

UNC5B
Netrin receptor UNC5B

1

14

High-throughput

0.618

High

729332

SH3K1
SH3 domain-containing kinase-binding protein 1

1

20

High-throughput

0.618

High

729340

SRPK1
SRSF protein kinase 1

1

20

High-throughput

0.618

High

729350

OSBL8
Oxysterol-binding protein-related protein 8

1

5

High-throughput

0.618

High

729403

S23IP
SEC23-interacting protein

1

10

High-throughput

0.618

High

437949

HS90B
Heat shock protein HSP 90-beta

2

20

High-throughput

0.611

High

572301

LEG3
Galectin-3

2

6

High-throughput

0.611

High

431595

HS90A
Heat shock protein HSP 90-alpha

2

20

High-throughput

0.594

High

729402

NEMO
NF-kappa-B essential modulator

1

7

High-throughput

0.561

High

729276

SNTB1
Beta-1-syntrophin

1

20

High-throughput

0.553

High

729312

PDZD8
PDZ domain-containing protein 8

1

2

High-throughput

0.553

High

729359

LRC40
Leucine-rich repeat-containing protein 40

1

17

High-throughput

0.553

High

729387

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

15

High-throughput

0.553

High

729317

DUS19
Dual specificity protein phosphatase 19

1

20

High-throughput

0.541

High

208449

OX2R
Orexin receptor type 2

1

1

High-throughput

0.536

High

335055

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

1

High-throughput

0.536

High

449210

LEG1
Galectin-1

1

6

High-throughput

0.536

High

591197

ACM3
Muscarinic acetylcholine receptor M3

1

2

High-throughput

0.536

High

653500

CALR
Calreticulin

1

14

High-throughput

0.536

High

729245

COPD
Coatomer subunit delta

1

4

High-throughput

0.536

High

729259

X3CL1
Fractalkine

1

1

High-throughput

0.536

High

729260

PRKDC
DNA-dependent protein kinase catalytic subunit

1

10

High-throughput

0.536

High

729287

CDC37
Hsp90 co-chaperone Cdc37

1

14

High-throughput

0.536

High

729382

CLC4A
C-type lectin domain family 4 member A

1

9

High-throughput

0.536

High

118218

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.513

High

729293

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.513

High

729242

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

13

High-throughput

0.501

High

323617

BAG2
BAG family molecular chaperone regulator 2

1

2

High-throughput

0.500

High

381136

TBB4A
Tubulin beta-4A chain

1

6

High-throughput

0.500

High

501763

BIP
Endoplasmic reticulum chaperone BiP

1

8

High-throughput

0.500

High

729240

EAA1
Excitatory amino acid transporter 1

1

6

High-throughput

0.500

High

729248

EMD
Emerin

1

7

High-throughput

0.500

High

729256

COPZ1
Coatomer subunit zeta-1

1

3

High-throughput

0.500

High

729263

S25A3
Solute carrier family 25 member 3

1

3

High-throughput

0.500

High

729265

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

1

11

High-throughput

0.500

High

729268

LG3BP
Galectin-3-binding protein

1

9

High-throughput

0.500

High

729295

S27A3
Long-chain fatty acid transport protein 3

1

1

High-throughput

0.500

High

729296

ATD3B
ATPase family AAA domain-containing protein 3B

1

5

High-throughput

0.500

High

729297

CROCC
Rootletin

1

5

High-throughput

0.500

High

729333

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

10

High-throughput

0.500

High

729346

NTPCR
Cancer-related nucleoside-triphosphatase

1

7

High-throughput

0.500

High

729378

FBW1B
F-box/WD repeat-containing protein 11

1

8

High-throughput

0.500

High

729388

ITM2B
Integral membrane protein 2B

1

2

High-throughput

0.500

High

50102

HACL2
2-hydroxyacyl-CoA lyase 2

1

1

High-throughput

0.489

High

130452

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

5

High-throughput

0.489

High

531749

PDIA4
Protein disulfide-isomerase A4

1

13

High-throughput

0.489

High

532068

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

4

High-throughput

0.489

High

654121

CALX
Calnexin

1

14

High-throughput

0.489

High

729255

S61A1
Protein transport protein Sec61 subunit alpha isoform 1

1

4

High-throughput

0.489

High

729277

TBB2A
Tubulin beta-2A chain

1

6

High-throughput

0.489

High

729291

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

4

High-throughput

0.489

High

729308

PLD3
5'-3' exonuclease PLD3

1

2

High-throughput

0.489

High

729347

TBB6
Tubulin beta-6 chain

1

6

High-throughput

0.489

High

729374

DJB11
DnaJ homolog subfamily B member 11

1

11

High-throughput

0.489

High

729272

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

0

High-throughput

0.479

High

729299

SFXN4
Sideroflexin-4

1

0

High-throughput

0.479

High

729318

THEM6
Protein THEM6

1

0

High-throughput

0.479

High

48281

ESYT2
Extended synaptotagmin-2

1

4

High-throughput

0.479

High

68544

NUD19
Acyl-coenzyme A diphosphatase NUDT19

1

6

High-throughput

0.479

High

117099

DX39A
ATP-dependent RNA helicase DDX39A

1

1

High-throughput

0.479

High

127198

IPO5
Importin-5

1

7

High-throughput

0.479

High

149565

COPE
Coatomer subunit epsilon

1

4

High-throughput

0.479

High

170808

PGRC2
Membrane-associated progesterone receptor component 2

1

5

High-throughput

0.479

High

207902

XPOT
Exportin-T

1

10

High-throughput

0.479

High

208533

TIM44
Mitochondrial import inner membrane translocase subunit TIM44

1

4

High-throughput

0.479

High

229325

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

7

High-throughput

0.479

High

240358

SNX2
Sorting nexin-2

1

14

High-throughput

0.479

High

240705

USO1
General vesicular transport factor p115

1

6

High-throughput

0.479

High

259704

PDCD6
Programmed cell death protein 6

1

2

High-throughput

0.479

High

264012

TACC1
Transforming acidic coiled-coil-containing protein 1

1

13

High-throughput

0.479

High

273706

NU155
Nuclear pore complex protein Nup155

1

8

High-throughput

0.479

High

295601

RMP
Unconventional prefoldin RPB5 interactor 1

1

1

High-throughput

0.479

High

302261

SC31A
Protein transport protein Sec31A

1

12

High-throughput

0.479

High

310529

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

15

High-throughput

0.479

High

311490

SMC2
Structural maintenance of chromosomes protein 2

1

11

High-throughput

0.479

High

314251

AHSA1
Activator of 90 kDa heat shock protein ATPase homolog 1

1

2

High-throughput

0.479

High

315527

SC24A
Protein transport protein Sec24A

1

20

High-throughput

0.479

High

315662

SC24B
Protein transport protein Sec24B

1

20

High-throughput

0.479

High

316588

ACSL3
Fatty acid CoA ligase Acsl3

1

1

High-throughput

0.479

High

320822

HS74L
Heat shock 70 kDa protein 4L

1

9

High-throughput

0.479

High

398656

IF2A
Eukaryotic translation initiation factor 2 subunit 1

1

5

High-throughput

0.479

High

403807

ITB1
Integrin beta-1

1

12

Small-scale

0.479

High

438922

ASNS
Asparagine synthetase [glutamine-hydrolyzing]

1

4

High-throughput

0.479

High

541318

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

5

High-throughput

0.479

High

571681

PFKAL
ATP-dependent 6-phosphofructokinase, liver type

1

11

High-throughput

0.479

High

574612

ARF4
ADP-ribosylation factor 4

1

13

High-throughput

0.479

High

588845

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

5

High-throughput

0.479

High

592634

RAB6A
Ras-related protein Rab-6A

1

7

High-throughput

0.479

High

595586

HXA5
Homeobox protein Hox-A5

1

4

High-throughput

0.479

High

681349

DNJA1
DnaJ homolog subfamily A member 1

1

16

High-throughput

0.479

High

725373

COPB2
Coatomer subunit beta'

1

9

High-throughput

0.479

High

729238

LONM
Lon protease homolog, mitochondrial

1

2

High-throughput

0.479

High

729239

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

8

High-throughput

0.479

High

729243

SYQ
Glutamine--tRNA ligase

1

3

High-throughput

0.479

High

729244

SC6A8
Sodium- and chloride-dependent creatine transporter 1

1

5

High-throughput

0.479

High

729251

AL3A2
Aldehyde dehydrogenase family 3 member A2

1

7

High-throughput

0.479

High

729252

COPB
Coatomer subunit beta

1

5

High-throughput

0.479

High

729253

COPA
Coatomer subunit alpha

1

9

High-throughput

0.479

High

729254

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

6

High-throughput

0.479

High

729257

ARF6
ADP-ribosylation factor 6

1

13

High-throughput

0.479

High

729264

PURA
Transcriptional activator protein Pur-alpha

1

2

High-throughput

0.479

High

729269

NSUN2
RNA cytosine C(5)-methyltransferase NSUN2

1

6

High-throughput

0.479

High

729270

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

3

High-throughput

0.479

High

729271

NDK3
Nucleoside diphosphate kinase 3

1

2

High-throughput

0.479

High

729274

STIM1
Stromal interaction molecule 1

1

9

High-throughput

0.479

High

729278

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

4

High-throughput

0.479

High

729279

SMC1A
Structural maintenance of chromosomes protein 1A

1

12

High-throughput

0.479

High

729280

CND2
Condensin complex subunit 2

1

3

High-throughput

0.479

High

729281

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

2

High-throughput

0.479

High

729282

SYK
Lysine--tRNA ligase

1

5

High-throughput

0.479

High

729283

SC23A
Protein transport protein Sec23A

1

20

High-throughput

0.479

High

729284

SC23B
Protein transport protein Sec23B

1

20

High-throughput

0.479

High

729285

PCH2
Pachytene checkpoint protein 2 homolog

1

4

High-throughput

0.479

High

729288

VATF
V-type proton ATPase subunit F

1

1

High-throughput

0.479

High

729298

F1711
Protein FAM171A1

1

17

High-throughput

0.479

High

729300

C1TM
Monofunctional C1-tetrahydrofolate synthase, mitochondrial

1

3

High-throughput

0.479

High

729302

DHX30
ATP-dependent RNA helicase DHX30

1

7

High-throughput

0.479

High

729304

MON2
Protein MON2 homolog

1

4

High-throughput

0.479

High

729305

RM10
Large ribosomal subunit protein uL10m

1

1

High-throughput

0.479

High

729306

PRUN1
Exopolyphosphatase PRUNE1

1

1

High-throughput

0.479

High

729311

NUP93
Nuclear pore complex protein Nup93

1

5

High-throughput

0.479

High

729313

NUP37
Nucleoporin Nup37

1

3

High-throughput

0.479

High

729314

NBEA
Neurobeachin

1

12

High-throughput

0.479

High

729315

DDX54
ATP-dependent RNA helicase DDX54

1

14

High-throughput

0.479

High

729319

SCFD1
Sec1 family domain-containing protein 1

1

9

High-throughput

0.479

High

729321

LIPH
Lipase member H

1

2

High-throughput

0.479

High

729322

DNJC9
DnaJ homolog subfamily C member 9

1

20

High-throughput

0.479

High

729325

HS105
Heat shock protein 105 kDa

1

18

High-throughput

0.479

High

729326

GCN1
Stalled ribosome sensor GCN1

1

8

High-throughput

0.479

High

729327

NU205
Nuclear pore complex protein Nup205

1

7

High-throughput

0.479

High

729329

TFG
Protein TFG

1

13

High-throughput

0.479

High

729330

ARHG2
Rho guanine nucleotide exchange factor 2

1

20

High-throughput

0.479

High

729331

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

4

High-throughput

0.479

High

729334

DDX27
Probable ATP-dependent RNA helicase DDX27

1

14

High-throughput

0.479

High

729335

DDRGK
DDRGK domain-containing protein 1

1

3

High-throughput

0.479

High

729336

CK5P3
CDK5 regulatory subunit-associated protein 3

1

4

High-throughput

0.479

High

729338

RBM14
RNA-binding protein 14

1

7

High-throughput

0.479

High

729343

MMS19
MMS19 nucleotide excision repair protein homolog

1

3

High-throughput

0.479

High

729344

TTC1
Tetratricopeptide repeat protein 1

1

7

High-throughput

0.479

High

729345

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

6

High-throughput

0.479

High

729351

EGLN1
Egl nine homolog 1

1

2

High-throughput

0.479

High

729352

DDX47
Probable ATP-dependent RNA helicase DDX47

1

9

High-throughput

0.479

High

729354

RBGPR
Rab3 GTPase-activating protein non-catalytic subunit

1

3

High-throughput

0.479

High

729357

UN45A
Protein unc-45 homolog A

1

7

High-throughput

0.479

High

729358

YTDC2
3'-5' RNA helicase YTHDC2

1

7

High-throughput

0.479

High

729360

XPO5
Exportin-5

1

10

High-throughput

0.479

High

729361

CYBP
Calcyclin-binding protein

1

3

High-throughput

0.479

High

729362

VEZA
Vezatin

1

3

High-throughput

0.479

High

729365

ARFG3
ADP-ribosylation factor GTPase-activating protein 3

1

19

High-throughput

0.479

High

729367

DD19A
ATP-dependent RNA helicase DDX19A

1

4

High-throughput

0.479

High

729368

FANCI
Fanconi anemia group I protein

1

7

High-throughput

0.479

High

729371

DDX56
Probable ATP-dependent RNA helicase DDX56

1

12

High-throughput

0.479

High

729372

SYLC
Leucine--tRNA ligase, cytoplasmic

1

8

High-throughput

0.479

High

729373

COPG2
Coatomer subunit gamma-2

1

5

High-throughput

0.479

High

729377

STML2
Stomatin-like protein 2, mitochondrial

1

3

High-throughput

0.479

High

729380

RAB21
Ras-related protein Rab-21

1

10

High-throughput

0.479

High

729381

FZR1
Fizzy-related protein homolog

1

7

High-throughput

0.479

High

729384

SNX6
Sorting nexin-6

1

14

High-throughput

0.479

High

729385

TTF2
Transcription termination factor 2

1

13

High-throughput

0.479

High

729386

SMC3
Structural maintenance of chromosomes protein 3

1

11

High-throughput

0.479

High

729389

SGT1
Protein SGT1 homolog

1

7

High-throughput

0.479

High

729392

HYOU1
Hypoxia up-regulated protein 1

1

19

High-throughput

0.479

High

729393

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

2

High-throughput

0.479

High

729397

RT18B
Small ribosomal subunit protein mS40

1

1

High-throughput

0.479

High

729398

COPG1
Coatomer subunit gamma-1

1

5

High-throughput

0.479

High

729399

SAR1B
Small COPII coat GTPase SAR1B

1

18

High-throughput

0.479

High

729400

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

1

3

High-throughput

0.479

High

729401

EPN1
Epsin-1

1

15

Small-scale

0.479

High

217749

CXL13
C-X-C motif chemokine 13

1

0

High-throughput

0.458

High

352513

TNFA
Tumor necrosis factor

1

0

High-throughput

0.458

High

676825

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

0

High-throughput

0.458

High

729250

FXR2
RNA-binding protein FXR2

1

0

High-throughput

0.458

High

729376

VATH
V-type proton ATPase subunit H

1

0

High-throughput

0.458

High

729383

MAGD2
Melanoma-associated antigen D2

1

0

High-throughput

0.458

High

729301

MCAF1
Activating transcription factor 7-interacting protein 1

1

7

High-throughput

0.457

High

71079

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

9

High-throughput

0.457

High

161030

CLGN
Calmegin

1

14

High-throughput

0.457

High

729320

FACR1
Fatty acyl-CoA reductase 1

1

1

High-throughput

0.457

High

729353

GHC2
Mitochondrial glutamate carrier 2

1

3

High-throughput

0.457

High

729292

H90B2
Putative heat shock protein HSP 90-beta 2

1

20

High-throughput

0.445

High

68147

F1712
Protein FAM171A2

1

17

High-throughput

0.437

High

240534

DPM1
Dolichol-phosphate mannosyltransferase subunit 1

1

10

High-throughput

0.437

High

242817

TRI13
E3 ubiquitin-protein ligase TRIM13

1

3

High-throughput

0.437

High

438705

SRPRA
Signal recognition particle receptor subunit alpha

1

6

High-throughput

0.437

High

451853

CN37
2',3'-cyclic-nucleotide 3'-phosphodiesterase

1

5

High-throughput

0.437

High

671733

PDIA3
Protein disulfide-isomerase A3

1

15

High-throughput

0.437

High

729249

SERPH
Serpin H1

1

6

High-throughput

0.437

High

729261

RT05
Small ribosomal subunit protein uS5m

1

3

High-throughput

0.437

High

729262

RT09
Small ribosomal subunit protein uS9m

1

2

High-throughput

0.437

High

729275

FHL3
Four and a half LIM domains protein 3

1

12

High-throughput

0.437

High

729286

RM23
Large ribosomal subunit protein uL23m

1

1

High-throughput

0.437

High

729294

TGO1
Transport and Golgi organization protein 1 homolog

1

4

High-throughput

0.437

High

729303

TRM1L
TRMT1-like protein

1

2

High-throughput

0.437

High

729309

NUDC3
NudC domain-containing protein 3

1

2

High-throughput

0.437

High

729316

IPO4
Importin-4

1

7

High-throughput

0.437

High

729323

RT27
Small ribosomal subunit protein mS27

1

2

High-throughput

0.437

High

729324

AP3S1
AP-3 complex subunit sigma-1

1

4

High-throughput

0.437

High

729328

RT31
Small ribosomal subunit protein mS31

1

3

High-throughput

0.437

High

729337

DAA10
Dynein axonemal assembly factor 10

1

1

High-throughput

0.437

High

729339

CLCC1
Chloride channel CLIC-like protein 1

1

5

High-throughput

0.437

High

729341

STRBP
Spermatid perinuclear RNA-binding protein

1

3

High-throughput

0.437

High

729342

TM209
Transmembrane protein 209

1

2

High-throughput

0.437

High

729356

GCP60
Golgi resident protein GCP60

1

11

High-throughput

0.437

High

729363

SDF2L
Stromal cell-derived factor 2-like protein 1

1

5

High-throughput

0.437

High

729364

APMAP
Adipocyte plasma membrane-associated protein

1

2

High-throughput

0.437

High

729366

SAR1A
Small COPII coat GTPase SAR1A

1

13

High-throughput

0.437

High

729369

PIHD1
PIH1 domain-containing protein 1

1

1

High-throughput

0.437

High

729370

NSMA3
Sphingomyelin phosphodiesterase 4

1

1

High-throughput

0.437

High

729375

SEC63
Translocation protein SEC63 homolog

1

13

High-throughput

0.437

High

729379

MRT4
mRNA turnover protein 4 homolog

1

4

High-throughput

0.437

High

729390

ACOT9
Acyl-coenzyme A thioesterase 9, mitochondrial

1

1

High-throughput

0.437

High

729395

SRPRB
Signal recognition particle receptor subunit beta

1

20

High-throughput

0.437

High

729396

ALG5
Dolichyl-phosphate beta-glucosyltransferase

1

4

High-throughput

0.437

High

729290

TM52B
Transmembrane protein 52B

3

0

High-throughput

0.347

High

729267

EF1A2
Elongation factor 1-alpha 2

1

0

High-throughput

0.279

Low

729348

PBDC1
Protein PBDC1

1

0

High-throughput

0.279

Low

729355

SPNS1
Protein spinster homolog 1

1

0

High-throughput

0.261

Low

729349

PLVAP
Plasmalemma vesicle-associated protein

1

0

High-throughput

0.249

Low

729391

RT23
Small ribosomal subunit protein mS23

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024