Protein: METL9
Protein-L-histidine N-pros-methyltransferase (EC 2.1.1.-) (DORA reverse strand protein) (DREV) (DREV1) (Methyltransferase-like protein 9) (hMETTL9)

Gene: METL9, METTL9
Organism: Homo sapiens
Interactions: 92
UniProt ID: Q9H1A3

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005783 - endoplasmic reticulum
GO:0032259 - methylation
GO:0106370 - protein-L-histidine N-pros-methyltransferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

699109

CALX
Calnexin

3

1

High-throughput

0.662

High

1430893

ZNT1
Proton-coupled zinc antiporter SLC30A1

3

5

High-throughput

0.643

High

1242929

S39A4
Zinc transporter ZIP4

4

7

High-throughput

0.630

High

1251801

S39A5
Zinc transporter ZIP5

3

7

High-throughput

0.604

High

1416209

FUND2
FUN14 domain-containing protein 2

2

1

High-throughput

0.601

High

1291891

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

3

1

High-throughput

0.593

High

166411

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

3

5

High-throughput

0.587

High

1346784

ZNT5
Proton-coupled zinc antiporter SLC30A5

3

5

High-throughput

0.587

High

1411143

ZNT2
Proton-coupled zinc antiporter SLC30A2

3

5

High-throughput

0.587

High

1430892

S39AA
Zinc transporter ZIP10

3

7

High-throughput

0.587

High

160762

TOR1A
Torsin-1A

2

0

High-throughput

0.576

High

1421123

LNP
Endoplasmic reticulum junction formation protein lunapark

2

0

High-throughput

0.576

High

1337948

ZNT7
Zinc transporter 7

2

5

High-throughput

0.552

High

1363443

S39A7
Zinc transporter SLC39A7

2

7

High-throughput

0.552

High

1239548

ZNT6
Zinc transporter 6

2

5

High-throughput

0.549

High

351964

S1PR4
Sphingosine 1-phosphate receptor 4

1

1

High-throughput

0.536

High

1309032

FUND1
FUN14 domain-containing protein 1

1

1

High-throughput

0.536

High

1430890

CLC2D
C-type lectin domain family 2 member D

1

1

High-throughput

0.536

High

521000

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

0

High-throughput

0.513

High

1231142

SCAR3
Scavenger receptor class A member 3

1

0

High-throughput

0.513

High

1272625

PCAT2
Lysophosphatidylcholine acyltransferase 2

1

0

High-throughput

0.513

High

1324860

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.513

High

466966

ACM4
Muscarinic acetylcholine receptor M4

1

1

High-throughput

0.494

High

1430880

MYG1
MYG1 exonuclease

1

0

High-throughput

0.493

High

833868

P2RY2
P2Y purinoceptor 2

1

1

High-throughput

0.489

High

1363142

CLC2B
C-type lectin domain family 2 member B

1

1

High-throughput

0.489

High

1430881

LPAR2
Lysophosphatidic acid receptor 2

1

1

High-throughput

0.489

High

1416855

TACAN
Transmembrane protein 120A

1

1

High-throughput

0.479

High

1430876

UN93B
Protein unc-93 homolog B1

1

1

High-throughput

0.479

High

1430884

PLCC
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma

1

1

High-throughput

0.479

High

170952

CLGN
Calmegin

1

1

High-throughput

0.445

High

934281

BI1
Bax inhibitor 1

1

1

High-throughput

0.445

High

1027175

REEP5
Receptor expression-enhancing protein 5

1

1

High-throughput

0.445

High

1105239

S39A6
Zinc transporter ZIP6

1

7

High-throughput

0.445

High

1248660

LCLT1
Lysocardiolipin acyltransferase 1

1

1

High-throughput

0.445

High

1393444

REEP6
Receptor expression-enhancing protein 6

1

1

High-throughput

0.445

High

1430877

GHITM
Growth hormone-inducible transmembrane protein

1

1

High-throughput

0.445

High

49695

T120B
Transmembrane protein 120B

1

1

High-throughput

0.437

High

1412859

YIPF4
Protein YIPF4

1

0

High-throughput

0.426

High

1430888

SE1L1
Protein sel-1 homolog 1

1

0

High-throughput

0.426

High

1430891

STML2
Stomatin-like protein 2, mitochondrial

1

0

High-throughput

0.426

High

1139563

S39AE
Metal cation symporter ZIP14

1

7

High-throughput

0.407

High

1323764

S39AB
Zinc transporter ZIP11

1

7

High-throughput

0.407

High

1392713

S39AD
Zinc transporter ZIP13

1

7

High-throughput

0.407

High

1294760

LYPD6
Ly6/PLAUR domain-containing protein 6

3

0

High-throughput

0.347

High

1322257

GNT2A
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase

3

0

High-throughput

0.347

High

1430878

DPEP2
Dipeptidase 2

3

0

High-throughput

0.347

High

1239292

ARMC6
Armadillo repeat-containing protein 6

3

0

High-throughput

0.345

High

1084023

SIA4A
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1

2

0

High-throughput

0.328

High

1430879

SPRNG
SREBP regulating gene protein

2

0

High-throughput

0.328

High

1430889

ACHA9
Neuronal acetylcholine receptor subunit alpha-9

2

0

High-throughput

0.318

High

1428293

PITH1
PITH domain-containing protein 1

2

0

High-throughput

0.313

High

1430885

MDN1
Midasin

2

0

High-throughput

0.313

High

171575

S27A2
Long-chain fatty acid transport protein 2

1

0

High-throughput

0.279

Low

270049

XYLK
Glycosaminoglycan xylosylkinase

1

0

High-throughput

0.279

Low

355377

B3GT4
Beta-1,3-galactosyltransferase 4

1

0

High-throughput

0.279

Low

555820

ACE
Angiotensin-converting enzyme

1

0

High-throughput

0.279

Low

592742

LEUK
Leukosialin

1

0

High-throughput

0.279

Low

689964

IL3RA
Interleukin-3 receptor subunit alpha

1

0

High-throughput

0.279

Low

700803

DMB
HLA class II histocompatibility antigen, DM beta chain

1

0

High-throughput

0.279

Low

749276

CD70
CD70 antigen

1

0

High-throughput

0.279

Low

1057697

TNR9
Tumor necrosis factor receptor superfamily member 9

1

0

High-throughput

0.279

Low

1088791

NMDE1
Glutamate receptor ionotropic, NMDA 2A

1

0

High-throughput

0.279

Low

1185898

TMM95
Sperm-egg fusion protein TMEM95

1

0

High-throughput

0.279

Low

1191796

VMA21
Vacuolar ATPase assembly integral membrane protein VMA21

1

0

High-throughput

0.279

Low

1225910

STEA3
Metalloreductase STEAP3

1

0

High-throughput

0.279

Low

1248605

LYPD5
Ly6/PLAUR domain-containing protein 5

1

0

High-throughput

0.279

Low

1249847

BTNL9
Butyrophilin-like protein 9

1

0

High-throughput

0.279

Low

1349114

F174A
Membrane protein FAM174A

1

0

High-throughput

0.279

Low

1349409

ADA32
Disintegrin and metalloproteinase domain-containing protein 32

1

0

High-throughput

0.279

Low

1430887

P2RX2
P2X purinoceptor 2

1

0

High-throughput

0.279

Low

1391146

CHMP6
Charged multivesicular body protein 6

1

0

High-throughput

0.265

Low

218752

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

551251

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.249

Low

1143672

NOMO1
BOS complex subunit NOMO1

1

0

High-throughput

0.249

Low

1315407

TEFF1
Tomoregulin-1

1

0

High-throughput

0.249

Low

1381345

NCLN
BOS complex subunit NCLN

1

0

High-throughput

0.249

Low

1391355

WBP1
WW domain-binding protein 1

1

0

High-throughput

0.249

Low

1430883

SERC1
Serine incorporator 1

1

0

High-throughput

0.249

Low

1430886

ARL15
ADP-ribosylation factor-like protein 15

1

0

High-throughput

0.249

Low

67504

ZSWM8
Zinc finger SWIM domain-containing protein 8

1

0

High-throughput

0.232

Low

292739

RENR
Renin receptor

1

0

High-throughput

0.232

Low

316564

B3GA3
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3

1

0

High-throughput

0.232

Low

687130

MGAT1
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

1

0

High-throughput

0.232

Low

704075

5HT1E
5-hydroxytryptamine receptor 1E

1

0

High-throughput

0.232

Low

845129

EAA3
Excitatory amino acid transporter 3

1

0

High-throughput

0.232

Low

890887

TSC2
Tuberin

1

0

High-throughput

0.232

Low

1153434

CD226
CD226 antigen

1

0

High-throughput

0.232

Low

1155265

VAS1
V-type proton ATPase subunit S1

1

0

High-throughput

0.232

Low

1234002

ASPH2
Aspartate beta-hydroxylase domain-containing protein 2

1

0

High-throughput

0.232

Low

1253796

QSOX2
Sulfhydryl oxidase 2

1

0

High-throughput

0.232

Low

1430882

SO1B3
Solute carrier organic anion transporter family member 1B3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025