Protein: NRF1
Nuclear respiratory factor 1 (NRF-1) (Alpha palindromic-binding protein) (Alpha-pal)

Gene: NRF1
Organism: Homo sapiens
Interactions: 66
UniProt ID: Q16656

Gene Ontology (top 5):
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1160974

POGZ
Pogo transposable element with ZNF domain

4

0

High-throughput

0.677

High

1036846

SP4
Transcription factor Sp4

3

2

High-throughput

0.675

High

1122980

FHL2
Four and a half LIM domains protein 2

4

0

High-throughput

0.674

High

1090670

TRAF2
TNF receptor-associated factor 2

3

0

High-throughput

0.646

High

991549

DYL1
Dynein light chain 1, cytoplasmic

2

1

Small-scale

0.639

High

995062

CSK2B
Casein kinase II subunit beta

3

0

Small-scale

0.625

High

965459

LMO4
LIM domain transcription factor LMO4

2

3

High-throughput

0.606

High

1034874

SP2
Transcription factor Sp2

2

2

High-throughput

0.606

High

1160983

LMBL2
Lethal(3)malignant brain tumor-like protein 2

2

1

High-throughput

0.606

High

1160986

LMBL3
Lethal(3)malignant brain tumor-like protein 3

2

1

High-throughput

0.606

High

1160988

SPSB2
SPRY domain-containing SOCS box protein 2

2

1

High-throughput

0.606

High

1160997

LHX3
LIM/homeobox protein Lhx3

2

4

High-throughput

0.606

High

1160998

KLF15
Krueppel-like factor 15

2

1

High-throughput

0.606

High

1161000

LHX6
LIM/homeobox protein Lhx6

2

3

High-throughput

0.606

High

1160971

WDR59
GATOR2 complex protein WDR59

2

0

High-throughput

0.602

High

156455

ACPM
Acyl carrier protein, mitochondrial

2

0

High-throughput

0.580

High

179051

IMA6
Importin subunit alpha-6

2

0

High-throughput

0.580

High

345186

ZMYM6
Zinc finger MYM-type protein 6

2

0

High-throughput

0.580

High

1007478

KRT83
Keratin, type II cuticular Hb3

2

0

High-throughput

0.580

High

1120669

VEZF1
Vascular endothelial zinc finger 1

2

0

High-throughput

0.580

High

1131952

MVP
Major vault protein

2

0

High-throughput

0.580

High

1160970

BICRL
BRD4-interacting chromatin-remodeling complex-associated protein-like

2

0

High-throughput

0.580

High

1160975

KHDC4
KH homology domain-containing protein 4

2

0

High-throughput

0.580

High

1160979

SRARP
Steroid receptor-associated and regulated protein

2

0

High-throughput

0.580

High

1160989

BBS2
BBSome complex member BBS2

2

0

High-throughput

0.580

High

1160991

TOLIP
Toll-interacting protein

2

0

High-throughput

0.580

High

1160994

BRWD1
Bromodomain and WD repeat-containing protein 1

2

0

High-throughput

0.580

High

1161001

TRI35
E3 ubiquitin-protein ligase TRIM35

2

0

High-throughput

0.580

High

1161002

MTL5
Tesmin

2

0

High-throughput

0.580

High

1160996

PRGC1
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha

1

1

Small-scale

0.561

High

606829

CEBPB
CCAAT/enhancer-binding protein beta

2

0

Small-scale

0.559

High

956877

CXCR4
C-X-C chemokine receptor type 4

2

0

Small-scale

0.559

High

211570

SIAH2
E3 ubiquitin-protein ligase SIAH2

1

0

Small-scale

0.554

High

997748

CSK21
Casein kinase II subunit alpha

1

0

Small-scale

0.537

High

854080

KI67
Proliferation marker protein Ki-67

1

1

High-throughput

0.536

High

1160984

DYL2
Dynein light chain 2, cytoplasmic

1

1

High-throughput

0.536

High

1160990

FOXP3
Forkhead box protein P3

1

2

High-throughput

0.536

High

1160995

FOXJ2
Forkhead box protein J2

1

1

High-throughput

0.536

High

1029687

FOXK2
Forkhead box protein K2

1

0

High-throughput

0.513

High

664756

CCND1
G1/S-specific cyclin-D1

1

1

Small-scale

0.506

High

1160969

PPRC1
Peroxisome proliferator-activated receptor gamma coactivator-related protein 1

1

1

Small-scale

0.501

High

1160993

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

0

Small-scale

0.493

High

1160980

APBB2
Amyloid beta precursor protein binding family B member 2

1

0

High-throughput

0.493

High

1160982

LHX4
LIM/homeobox protein Lhx4

1

4

High-throughput

0.481

High

487366

PARP1
Poly [ADP-ribose] polymerase 1

1

0

Small-scale

0.480

High

1160999

MAFF
Transcription factor MafF

1

0

Small-scale

0.480

High

1126853

NF2L1
Endoplasmic reticulum membrane sensor NFE2L1

1

2

Small-scale

0.479

High

1160967

Q495U3
PANX2 protein

1

1

High-throughput

0.470

High

586305

ZEP1
Zinc finger protein 40

1

0

High-throughput

0.460

High

1160978

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

0

High-throughput

0.458

High

1160981

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

0

Small-scale

0.458

High

3507

A0A0S2Z5S9
LIM homeobox 4 isoform 2

1

4

High-throughput

0.457

High

1160987

PANX2
Pannexin-2

1

1

High-throughput

0.439

High

1056754

FMR1
Fragile X messenger ribonucleoprotein 1

1

0

High-throughput

0.438

High

353362

AGR2
Anterior gradient protein 2 homolog

2

0

High-throughput

0.316

High

605139

KCRS
Creatine kinase S-type, mitochondrial

2

0

High-throughput

0.316

High

1043626

COAA1

2

0

High-throughput

0.316

High

1160966

CC036
Uncharacterized protein C3orf36

2

0

High-throughput

0.316

High

1160968

CJ055
Uncharacterized protein C10orf55

2

0

High-throughput

0.316

High

1160972

SMI10
Sperm-associated microtubule inner protein 10

2

0

High-throughput

0.316

High

1160977

BWR1B
Uncharacterized protein SLC67A1-AS

2

0

High-throughput

0.316

High

1160985

HIPL1
HHIP-like protein 1

2

0

High-throughput

0.316

High

1160992

ESM1
Endothelial cell-specific molecule 1

2

0

High-throughput

0.316

High

959475

YPEL3
Protein yippee-like 3

1

0

High-throughput

0.251

Low

1160976

PLDX1
Plexin domain-containing protein 1

1

0

High-throughput

0.251

Low

1160973

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025