Protein: INSL5
Insulin-like peptide INSL5 (Insulin-like peptide 5) [Cleaved into: Insulin-like peptide INSL5 B chain; Insulin-like peptide INSL5 A chain]

Gene: INSL5
Organism: Homo sapiens
Interactions: 56
UniProt ID: Q9Y5Q6

Gene Ontology (top 5):
GO:0001664 - G protein-coupled receptor binding
GO:0005179 - hormone activity
GO:0005576 - extracellular region
GO:2000253 - positive regulation of feeding behavior

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1052186

COEA1
Collagen alpha-1(XIV) chain

1

1

High-throughput

0.691

High

1366083

PXDN
Peroxidasin homolog

1

1

High-throughput

0.691

High

439891

INSR
Insulin receptor

2

0

High-throughput

0.679

High

215735

COCH
Cochlin

2

3

High-throughput

0.628

High

551832

CO6A1

2

2

High-throughput

0.628

High

551904

CO6A2

2

2

High-throughput

0.628

High

586392

ARSB
Arylsulfatase B

2

4

High-throughput

0.628

High

1248938

ARSK
Arylsulfatase K

2

4

High-throughput

0.628

High

1419512

CNTP3
Contactin-associated protein-like 3

2

1

High-throughput

0.628

High

1292566

AMGO1
Amphoterin-induced protein 1

1

2

High-throughput

0.618

High

1394731

LRIG1
Leucine-rich repeats and immunoglobulin-like domains protein 1

1

1

High-throughput

0.618

High

1369118

PCSK5
Proprotein convertase subtilisin/kexin type 5

2

0

High-throughput

0.602

High

1006236

CNTP1
Contactin-associated protein 1

2

1

High-throughput

0.574

High

1008463

ADA17
Disintegrin and metalloproteinase domain-containing protein 17

2

1

High-throughput

0.574

High

1105793

ADAM9
Disintegrin and metalloproteinase domain-containing protein 9

2

1

High-throughput

0.574

High

1311067

SULF1
Extracellular sulfatase Sulf-1

2

4

High-throughput

0.574

High

1311136

UBR1
E3 ubiquitin-protein ligase UBR1

2

1

High-throughput

0.574

High

1311196

UBR2
E3 ubiquitin-protein ligase UBR2

2

1

High-throughput

0.574

High

183313

LAMA5
Laminin subunit alpha-5

1

3

High-throughput

0.536

High

582367

ARSA
Arylsulfatase A

1

4

High-throughput

0.536

High

756596

GALNS
N-acetylgalactosamine-6-sulfatase

1

4

High-throughput

0.536

High

937455

LAMB2
Laminin subunit beta-2

1

1

High-throughput

0.536

High

997210

TBA4A
Tubulin alpha-4A chain

1

2

High-throughput

0.536

High

284025

CAH11
Carbonic anhydrase-related protein 11

1

0

High-throughput

0.513

High

1259603

TBA1A
Tubulin alpha-1A chain

1

2

High-throughput

0.489

High

1410648

TBA1C
Tubulin alpha-1C chain

1

2

High-throughput

0.489

High

219835

CHSTA
Carbohydrate sulfotransferase 10

2

0

High-throughput

0.328

High

239505

H6ST1
Heparan-sulfate 6-O-sulfotransferase 1

2

0

High-throughput

0.328

High

269716

PLXA2
Plexin-A2

2

0

High-throughput

0.328

High

448081

ITAV
Integrin alpha-V

2

0

High-throughput

0.328

High

604412

ASM
Sphingomyelin phosphodiesterase

2

0

High-throughput

0.328

High

1108328

SQSTM
Sequestosome-1

2

0

High-throughput

0.328

High

1108773

TBB3
Tubulin beta-3 chain

2

0

High-throughput

0.328

High

1193221

OFUT4
GDP-fucose protein O-fucosyltransferase 4

2

0

High-throughput

0.328

High

1208468

EOGT
EGF domain-specific O-linked N-acetylglucosamine transferase

2

0

High-throughput

0.328

High

1212708

GT253
Inactive glycosyltransferase 25 family member 3

2

0

High-throughput

0.328

High

1248525

SUSD1
Sushi domain-containing protein 1

2

0

High-throughput

0.328

High

1249648

PXDC2
Plexin domain-containing protein 2

2

0

High-throughput

0.328

High

1292039

AMZ2
Archaemetzincin-2

2

0

High-throughput

0.328

High

1292156

ANR46
Ankyrin repeat domain-containing protein 46

2

0

High-throughput

0.328

High

1308862

P3H3
Prolyl 3-hydroxylase 3

2

0

High-throughput

0.328

High

1403185

INT14
Integrator complex subunit 14

2

0

High-throughput

0.328

High

1431738

SEM6A
Semaphorin-6A

2

0

High-throughput

0.328

High

1452235

CA2D2
Voltage-dependent calcium channel subunit alpha-2/delta-2

2

0

High-throughput

0.328

High

1458855

CATF
Cathepsin F

2

0

High-throughput

0.328

High

1460013

CEIP2
Cell surface hyaluronidase CEMIP2

2

0

High-throughput

0.328

High

1491421

LOXL2
Lysyl oxidase homolog 2

2

0

High-throughput

0.328

High

1086150

ASPH
Aspartyl/asparaginyl beta-hydroxylase

2

0

High-throughput

0.316

High

535724

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.279

Low

612131

ITB5
Integrin beta-5

1

0

High-throughput

0.279

Low

932399

ANAG
Alpha-N-acetylglucosaminidase

1

0

High-throughput

0.279

Low

1177257

MICA
MHC class I polypeptide-related sequence A

1

0

High-throughput

0.279

Low

1212886

UBR4
E3 ubiquitin-protein ligase UBR4

1

0

High-throughput

0.279

Low

1248299

MOXD1
DBH-like monooxygenase protein 1

1

0

High-throughput

0.279

Low

1260592

B4GN4
N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1

1

0

High-throughput

0.279

Low

1454659

TXD16
Thioredoxin domain-containing protein 16

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025