Protein: CNOT8
CCR4-NOT transcription complex subunit 8 (EC 3.1.13.4) (CAF1-like protein) (CALIFp) (CAF2) (CCR4-associated factor 8) (Caf1b)

Gene: CNOT8
Organism: Homo sapiens
Interactions: 77
UniProt ID: Q9UFF9

Gene Ontology (top 5):
GO:0000175 - 3'-5'-RNA exonuclease activity
GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0000932 - P-body
GO:0003723 - RNA binding
GO:0004535 - poly(A)-specific ribonuclease activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

61488

CNOT1
CCR4-NOT transcription complex subunit 1

6

8

Small-scale

0.950

High

912793

BTG1
Protein BTG1

6

19

Small-scale

0.944

High

944598

BTG2
Protein BTG2

2

19

Small-scale

0.837

High

841403

TOB1
Protein Tob1

2

19

High-throughput

0.811

High

1048316

TOB2
Protein Tob2

1

19

High-throughput

0.740

High

1297136

CNO6L
CCR4-NOT transcription complex subunit 6-like

5

14

Small-scale

0.713

High

1051204

BTG3
Protein BTG3

1

19

High-throughput

0.698

High

1349340

CNOT2
CCR4-NOT transcription complex subunit 2

4

9

Small-scale

0.691

High

257422

CNOT3
CCR4-NOT transcription complex subunit 3

3

12

Small-scale

0.680

High

813195

CAZA2
F-actin-capping protein subunit alpha-2

3

3

High-throughput

0.667

High

1152298

Q6IBC8
Protein BTG1

1

19

High-throughput

0.665

High

1336204

TNR6C
Trinucleotide repeat-containing gene 6C protein

3

8

Small-scale

0.656

High

258876

GA45B
Growth arrest and DNA damage-inducible protein GADD45 beta

2

1

High-throughput

0.628

High

888504

NANO2
Nanos homolog 2

2

4

High-throughput

0.628

High

1315786

TX13A
Testis-expressed protein 13A

2

1

High-throughput

0.628

High

1335759

GPBL1
Vasculin-like protein 1

2

2

High-throughput

0.628

High

1354672

CNO11
CCR4-NOT transcription complex subunit 11

2

1

High-throughput

0.628

High

1334109

CNO10
CCR4-NOT transcription complex subunit 10

2

1

High-throughput

0.621

High

160829

AURKA
Aurora kinase A

2

1

High-throughput

0.611

High

813814

CAPZB
F-actin-capping protein subunit beta

2

1

High-throughput

0.611

High

857240

CAZA1
F-actin-capping protein subunit alpha-1

2

3

High-throughput

0.611

High

448894

MMP7
Matrilysin

3

1

High-throughput

0.609

High

1242678

TNR6A
Trinucleotide repeat-containing gene 6A protein

2

6

Small-scale

0.601

High

1354674

TNR6B
Trinucleotide repeat-containing gene 6B protein

2

6

Small-scale

0.601

High

1056768

PUM1
Pumilio homolog 1

2

9

Small-scale

0.595

High

358922

CRYAA
Alpha-crystallin A chain

2

0

High-throughput

0.592

High

644343

TTP
mRNA decay activator protein ZFP36

2

6

Small-scale

0.584

High

1136339

RC3H1
Roquin-1

2

4

Small-scale

0.584

High

1219257

Z3H7A
Zinc finger CCCH domain-containing protein 7A

2

1

High-throughput

0.584

High

1354673

CNOT6
CCR4-NOT transcription complex subunit 6

2

14

Small-scale

0.576

High

1232874

RIBC1
RIB43A-like with coiled-coils protein 1

2

1

High-throughput

0.574

High

370635

ESR1
Estrogen receptor

2

3

High-throughput

0.571

High

1307039

ANM1
Protein arginine N-methyltransferase 1

1

1

Small-scale

0.561

High

62102

EPAB2
Embryonic polyadenylate-binding protein 2

1

2

High-throughput

0.536

High

282256

SEGN
Secretagogin

1

1

High-throughput

0.536

High

792050

HD
Huntingtin

1

2

High-throughput

0.536

High

796197

MAGA9
Melanoma-associated antigen 9

1

1

High-throughput

0.536

High

1050834

FHL2
Four and a half LIM domains protein 2

1

2

High-throughput

0.536

High

786440

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

1

Small-scale

0.515

High

1354671

AGO2
Protein argonaute-2

1

6

Small-scale

0.515

High

454772

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.513

High

830303

CASP4
Caspase-4

1

0

High-throughput

0.513

High

317687

CNOT4
CCR4-NOT transcription complex subunit 4

1

3

Small-scale

0.501

High

1198403

PATL1
Protein PAT1 homolog 1

1

4

Small-scale

0.500

High

709101

MCM7
DNA replication licensing factor MCM7

1

0

High-throughput

0.493

High

599020

FPR1
fMet-Leu-Phe receptor

1

1

High-throughput

0.489

High

1264321

NANO1
Nanos homolog 1

1

4

High-throughput

0.489

High

1266856

TM131
Transmembrane protein 131

1

3

High-throughput

0.489

High

1299564

FACOS
FANCD2 opposite strand protein

1

1

High-throughput

0.489

High

166329

GRRE1
Granule associated Rac and RHOG effector protein 1

1

1

High-throughput

0.479

High

257715

ANR17
Ankyrin repeat domain-containing protein 17

1

1

High-throughput

0.479

High

377780

GCR
Glucocorticoid receptor

1

3

High-throughput

0.479

High

850224

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

1

High-throughput

0.479

High

1089578

CPEB4
Cytoplasmic polyadenylation element-binding protein 4

1

7

High-throughput

0.479

High

1139886

OBI1
ORC ubiquitin ligase 1

1

1

High-throughput

0.479

High

1168859

MEX3B
RNA-binding protein MEX3B

1

3

High-throughput

0.479

High

1192400

YTHD3
YTH domain-containing family protein 3

1

6

High-throughput

0.479

High

1267891

CNOT9
CCR4-NOT transcription complex subunit 9

1

5

High-throughput

0.479

High

1317752

CPEB1
Cytoplasmic polyadenylation element-binding protein 1

1

5

High-throughput

0.479

High

1318811

UNK
RING finger protein unkempt homolog

1

6

High-throughput

0.479

High

1335220

RC3H2
Roquin-2

1

6

Small-scale

0.479

High

1354675

YTHD2
YTH domain-containing family protein 2

1

6

High-throughput

0.479

High

323256

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

547260

EZRI
Ezrin

1

0

High-throughput

0.458

High

875400

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

1244739

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

1291595

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.458

High

1327140

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

1335125

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.458

High

1203481

LDHD
Probable D-lactate dehydrogenase, mitochondrial

1

1

High-throughput

0.437

High

1354676

GPR45
Probable G-protein coupled receptor 45

1

0

High-throughput

0.279

Low

49069

A0N4V7
HCG2039797

1

0

High-throughput

0.249

Low

252767

FCG3B
Low affinity immunoglobulin gamma Fc region receptor III-B

1

0

High-throughput

0.249

Low

670264

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.249

Low

1139586

LIPM
Lipase member M

1

0

High-throughput

0.249

Low

1260079

CT55
Cancer/testis antigen 55

1

0

High-throughput

0.249

Low

1331545

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024