Protein: TSSP
Thymus-specific serine protease (EC 3.4.-.-) (Serine protease 16)

Gene: TSSP, PRSS16
Organism: Homo sapiens
Interactions: 42
UniProt ID: Q9NQE7

Gene Ontology (top 5):
GO:0005764 - lysosome
GO:0005768 - endosome
GO:0006508 - proteolysis
GO:0008236 - serine-type peptidase activity
GO:0008239 - dipeptidyl-peptidase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

210789

KLK10
Kallikrein-10

1

2

High-throughput

0.536

High

892138

KLK7
Kallikrein-7

1

2

High-throughput

0.536

High

1447067

KLK5
Kallikrein-5

1

2

High-throughput

0.536

High

485820

CATH
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H

1

0

High-throughput

0.513

High

729621

CASPE
Caspase-14

1

0

High-throughput

0.513

High

1242367

PLBL1
Phospholipase B-like 1

1

0

High-throughput

0.513

High

1447066

CBPA4
Carboxypeptidase A4

1

0

High-throughput

0.513

High

220104

TGM5
Protein-glutamine gamma-glutamyltransferase 5

1

2

High-throughput

0.489

High

289283

SPB7
Serpin B7

1

5

High-throughput

0.489

High

369509

AACT
Alpha-1-antichymotrypsin

1

5

High-throughput

0.489

High

635641

FILA
Filaggrin

1

1

High-throughput

0.489

High

652419

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

2

High-throughput

0.489

High

713462

SPB3
Serpin B3

1

4

High-throughput

0.489

High

724636

S10A7
Protein S100-A7

1

2

High-throughput

0.489

High

874873

SPB4
Serpin B4

1

4

High-throughput

0.489

High

895469

SPB8
Serpin B8

1

4

High-throughput

0.489

High

1062299

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

2

High-throughput

0.489

High

1204034

FILA2
Filaggrin-2

1

1

High-throughput

0.489

High

1309623

SPA12
Serpin A12

1

5

High-throughput

0.489

High

1338071

DR9C7
Short-chain dehydrogenase/reductase family 9C member 7

1

1

High-throughput

0.489

High

477178

ACM5
Muscarinic acetylcholine receptor M5

1

0

High-throughput

0.282

High

276634

LX12B
Arachidonate 12-lipoxygenase, 12R-type

1

0

High-throughput

0.279

Low

551634

NFH
Neurofilament heavy polypeptide

1

0

High-throughput

0.279

Low

582625

PPAP
Prostatic acid phosphatase

1

0

High-throughput

0.279

Low

609336

SAP3
Ganglioside GM2 activator

1

0

High-throughput

0.279

Low

671862

ZA2G
Zinc-alpha-2-glycoprotein

1

0

High-throughput

0.279

Low

839631

HUTH
Histidine ammonia-lyase

1

0

High-throughput

0.279

Low

1036804

DSG1
Desmoglein-1

1

0

High-throughput

0.279

Low

1149557

CDSN
Corneodesmosin

1

0

High-throughput

0.279

Low

1154351

CYTM
Cystatin-M

1

0

High-throughput

0.279

Low

1207016

ZNG1C
Zinc-regulated GTPase metalloprotein activator 1C

1

0

High-throughput

0.279

Low

1213843

KPRP
Keratinocyte proline-rich protein

1

0

High-throughput

0.279

Low

1216315

MTCL3
Microtubule cross-linking factor 3

1

0

High-throughput

0.279

Low

1248742

SBSN
Suprabasin

1

0

High-throughput

0.279

Low

1358585

POF1B
Protein POF1B

1

0

High-throughput

0.279

Low

1396691

CPNS2
Calpain small subunit 2

1

0

High-throughput

0.279

Low

1400654

GSDMA
Gasdermin-A

1

0

High-throughput

0.279

Low

1413849

DHRS4
Dehydrogenase/reductase SDR family member 4

1

0

High-throughput

0.279

Low

1431046

RNAS7
Ribonuclease 7

1

0

High-throughput

0.279

Low

1447064

IL37
Interleukin-37

1

0

High-throughput

0.279

Low

888339

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.249

Low

1447065

AAKG2
5'-AMP-activated protein kinase subunit gamma-2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025