Protein: MACOI
Macoilin (Macoilin-1) (Transmembrane protein 57)

Gene: MACOI, MACO1
Organism: Homo sapiens
Interactions: 214
UniProt ID: Q8N5G2

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0006935 - chemotaxis
GO:0007420 - brain development
GO:0008017 - microtubule binding
GO:0023041 - neuronal signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

749792

CADH5
Cadherin-5

2

8

High-throughput

0.628

High

1159080

C3AR
C3a anaphylatoxin chemotactic receptor

2

4

High-throughput

0.628

High

1327755

PCDBB
Protocadherin beta-11

2

4

High-throughput

0.628

High

885336

HXA1
Homeobox protein Hox-A1

2

2

High-throughput

0.606

High

1327687

ZN655
Zinc finger protein 655

2

2

High-throughput

0.606

High

1327700

NR4A3
Nuclear receptor subfamily 4 group A member 3

2

16

High-throughput

0.606

High

1327756

PCDC2
Protocadherin alpha-C2

3

3

High-throughput

0.604

High

1327708

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

2

16

High-throughput

0.601

High

1327742

ACHA9
Neuronal acetylcholine receptor subunit alpha-9

2

0

High-throughput

0.585

High

1327698

TM190
Transmembrane protein 190

2

0

High-throughput

0.580

High

396509

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

380455

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

2

1

High-throughput

0.558

High

1212942

LCE3E
Late cornified envelope protein 3E

2

1

High-throughput

0.553

High

1213910

LCE1C
Late cornified envelope protein 1C

2

1

High-throughput

0.553

High

1213996

LCE1E
Late cornified envelope protein 1E

2

1

High-throughput

0.553

High

1327710

LIGO1
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1

2

6

High-throughput

0.553

High

182660

GP182
G-protein coupled receptor 182

2

4

High-throughput

0.549

High

1327695

ST7L
Suppressor of tumorigenicity 7 protein-like

2

1

High-throughput

0.549

High

1115814

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

20

High-throughput

0.536

High

1327753

PCDB6
Protocadherin beta-6

1

4

High-throughput

0.536

High

1327754

PCDB3
Protocadherin beta-3

1

3

High-throughput

0.536

High

951261

SC61B
Protein transport protein Sec61 subunit beta

2

1

High-throughput

0.533

High

1327703

PTPRU
Receptor-type tyrosine-protein phosphatase U

2

1

High-throughput

0.533

High

1327707

LRC59
Leucine-rich repeat-containing protein 59

2

9

High-throughput

0.533

High

65912

RHG42
Rho GTPase-activating protein 42

2

8

High-throughput

0.521

High

986565

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

6

High-throughput

0.515

High

1232461

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.515

High

1327706

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.513

High

1327729

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.513

High

181909

SMAD9
Mothers against decapentaplegic homolog 9

1

1

High-throughput

0.508

High

1006548

SRPK2
SRSF protein kinase 2

1

15

High-throughput

0.501

High

249930

NPHN
Nephrin

1

5

High-throughput

0.489

High

719811

V2R
Vasopressin V2 receptor

1

1

High-throughput

0.489

High

771792

SCN4A
Sodium channel protein type 4 subunit alpha

1

9

High-throughput

0.489

High

888918

TMEDA
Transmembrane emp24 domain-containing protein 10

1

1

High-throughput

0.489

High

1142101

P2RY6
P2Y purinoceptor 6

1

5

High-throughput

0.489

High

1206601

PLAC9
Placenta-specific protein 9

1

1

High-throughput

0.489

High

1251727

CERS6
Ceramide synthase 6

1

1

High-throughput

0.489

High

1254062

LRC55
Leucine-rich repeat-containing protein 55

1

4

High-throughput

0.489

High

1327492

CERS5
Ceramide synthase 5

1

1

High-throughput

0.489

High

1327712

CREL1
Protein disulfide isomerase CRELD1

1

1

High-throughput

0.489

High

894014

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.481

High

291432

NU155
Nuclear pore complex protein Nup155

1

1

High-throughput

0.479

High

408987

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

4

High-throughput

0.479

High

464008

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

4

High-throughput

0.479

High

466355

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.479

High

581165

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

604095

CXA1
Gap junction alpha-1 protein

1

6

High-throughput

0.479

High

631342

RAB5A
Ras-related protein Rab-5A

1

9

High-throughput

0.479

High

634527

LMNB1
Lamin-B1

1

11

High-throughput

0.479

High

691244

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

698880

CALX
Calnexin

1

3

High-throughput

0.479

High

704543

RXRB
Retinoic acid receptor RXR-beta

1

15

High-throughput

0.479

High

831063

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

837718

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

4

High-throughput

0.479

High

872530

SOX2
Transcription factor SOX-2

1

4

High-throughput

0.479

High

894895

EMD
Emerin

1

1

High-throughput

0.479

High

962267

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

976415

RB11A
Ras-related protein Rab-11A

1

5

High-throughput

0.479

High

979986

H4
Histone H4

1

8

High-throughput

0.479

High

990498

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.479

High

1087188

STX4
Syntaxin-4

1

4

High-throughput

0.479

High

1226173

CP135
Centrosomal protein of 135 kDa

1

17

High-throughput

0.479

High

1252127

SYNE3
Nesprin-3

1

20

High-throughput

0.479

High

1327714

DNJC1
DnaJ homolog subfamily C member 1

1

4

High-throughput

0.479

High

1327715

CNO6L
CCR4-NOT transcription complex subunit 6-like

1

5

High-throughput

0.479

High

1327718

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

1

High-throughput

0.479

High

1327737

CNOT2
CCR4-NOT transcription complex subunit 2

1

1

High-throughput

0.479

High

1327740

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

1327746

RALY
RNA-binding protein Raly

1

6

High-throughput

0.479

High

1327752

YTHD2
YTH domain-containing family protein 2

1

6

High-throughput

0.479

High

49167

POTB3
POTE ankyrin domain family member B3

1

7

High-throughput

0.470

High

517061

NT2NC
Notch homolog 2 N-terminal-like protein C

1

1

High-throughput

0.470

High

1288480

LBN
Limbin

1

0

High-throughput

0.458

High

1327702

CNOT9
CCR4-NOT transcription complex subunit 9

1

0

High-throughput

0.458

High

1327719

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.458

High

1327744

CNOT7
CCR4-NOT transcription complex subunit 7

1

0

High-throughput

0.458

High

1327748

MARE3
Microtubule-associated protein RP/EB family member 3

1

0

High-throughput

0.458

High

843764

HD
Huntingtin

1

4

High-throughput

0.457

High

1163965

DDR2
Discoidin domain-containing receptor 2

1

8

High-throughput

0.457

High

51457

FSD2
Fibronectin type III and SPRY domain-containing protein 2

1

11

High-throughput

0.445

High

255125

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

5

High-throughput

0.445

High

956941

CXCR4
C-X-C chemokine receptor type 4

1

2

High-throughput

0.445

High

1161149

MK06
Mitogen-activated protein kinase 6

1

12

High-throughput

0.445

High

1239875

CAVN1
Caveolae-associated protein 1

1

1

High-throughput

0.445

High

576

NBPFJ
NBPF family member NBPF19

1

17

High-throughput

0.439

High

1277311

NT2NA
Notch homolog 2 N-terminal-like protein A

1

1

High-throughput

0.439

High

1327723

LCE3D
Late cornified envelope protein 3D

1

1

High-throughput

0.439

High

126697

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.437

High

173992

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

5

High-throughput

0.437

High

189706

STX7
Syntaxin-7

1

4

High-throughput

0.437

High

226129

STX6
Syntaxin-6

1

2

High-throughput

0.437

High

375721

RASK
GTPase KRas

1

18

High-throughput

0.437

High

391354

FRIL
Ferritin light chain

1

3

High-throughput

0.437

High

417578

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.437

High

418266

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.437

High

436944

K1C18
Keratin, type I cytoskeletal 18

1

8

High-throughput

0.437

High

562226

LAMP2
Lysosome-associated membrane glycoprotein 2

1

5

High-throughput

0.437

High

570500

GFAP
Glial fibrillary acidic protein

1

12

High-throughput

0.437

High

611227

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

3

High-throughput

0.437

High

630574

RAB3B
Ras-related protein Rab-3B

1

8

High-throughput

0.437

High

630884

RAB4A
Ras-related protein Rab-4A

1

8

High-throughput

0.437

High

715674

MARCS
Myristoylated alanine-rich C-kinase substrate

1

5

High-throughput

0.437

High

880609

LMAN1
Protein ERGIC-53

1

1

High-throughput

0.437

High

900921

RAB5C
Ras-related protein Rab-5C

1

10

High-throughput

0.437

High

901386

RAB7A
Ras-related protein Rab-7a

1

12

High-throughput

0.437

High

901940

RAB9A
Ras-related protein Rab-9A

1

13

High-throughput

0.437

High

904006

BAP31
B-cell receptor-associated protein 31

1

12

High-throughput

0.437

High

910130

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.437

High

953563

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.437

High

955374

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.437

High

1004130

CXAR
Coxsackievirus and adenovirus receptor

1

4

High-throughput

0.437

High

1015595

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.437

High

1058525

CKAP4
Cytoskeleton-associated protein 4

1

18

High-throughput

0.437

High

1125540

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

5

High-throughput

0.437

High

1145013

RAB35
Ras-related protein Rab-35

1

9

High-throughput

0.437

High

1156546

CCDC6
Coiled-coil domain-containing protein 6

1

18

High-throughput

0.437

High

1208753

CL12A
C-type lectin domain family 12 member A

1

7

High-throughput

0.437

High

1219850

OBI1
ORC ubiquitin ligase 1

1

1

High-throughput

0.437

High

1228995

RNF43
E3 ubiquitin-protein ligase RNF43

1

7

High-throughput

0.437

High

1241906

FBX42
F-box only protein 42

1

8

High-throughput

0.437

High

1245094

RHDF2
Inactive rhomboid protein 2

1

1

High-throughput

0.437

High

1295488

MIB1
E3 ubiquitin-protein ligase MIB1

1

5

High-throughput

0.437

High

1312183

MIRO2
Mitochondrial Rho GTPase 2

1

20

High-throughput

0.437

High

1322891

CXD3
Gap junction delta-3 protein

1

6

High-throughput

0.437

High

1327691

PDZD8
PDZ domain-containing protein 8

1

1

High-throughput

0.437

High

1327694

BICD2
Protein bicaudal D homolog 2

1

19

High-throughput

0.437

High

1327696

RHBL4
Rhomboid-related protein 4

1

2

High-throughput

0.437

High

1327705

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

1

High-throughput

0.437

High

1327709

VP33A
Vacuolar protein sorting-associated protein 33A

1

3

High-throughput

0.437

High

1327711

BICD1
Protein bicaudal D homolog 1

1

18

High-throughput

0.437

High

1327720

SEC62
Translocation protein SEC62

1

1

High-throughput

0.437

High

1327721

ESYT1
Extended synaptotagmin-1

1

3

High-throughput

0.437

High

1327727

DJC25
DnaJ homolog subfamily C member 25

1

4

High-throughput

0.437

High

1327730

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.437

High

1327733

ST7
Suppressor of tumorigenicity 7 protein

1

1

High-throughput

0.437

High

1327734

TMPS4
Transmembrane protease serine 4

1

2

High-throughput

0.437

High

1327743

SEC63
Translocation protein SEC63 homolog

1

3

High-throughput

0.437

High

1327745

ANC2
Anaphase-promoting complex subunit 2

1

11

High-throughput

0.437

High

1327747

ALK
ALK tyrosine kinase receptor

1

8

High-throughput

0.437

High

1327749

LAMP3
Lysosome-associated membrane glycoprotein 3

1

4

High-throughput

0.437

High

1327751

DJC16
DnaJ homolog subfamily C member 16

1

6

High-throughput

0.437

High

1279058

RIC3
Protein RIC-3

1

0

High-throughput

0.426

High

351234

MOT3
Monocarboxylate transporter 3

1

2

High-throughput

0.407

High

1125997

LRC32
Transforming growth factor beta activator LRRC32

1

5

High-throughput

0.407

High

1139500

S39AE
Metal cation symporter ZIP14

1

7

High-throughput

0.407

High

1186411

ASTRB
Protein Aster-B

1

1

High-throughput

0.407

High

1211932

S35F1
Solute carrier family 35 member F1

1

1

High-throughput

0.407

High

1246087

GTR7
Solute carrier family 2, facilitated glucose transporter member 7

1

1

High-throughput

0.407

High

1309754

CTL2
Choline transporter-like protein 2

1

2

High-throughput

0.407

High

1316325

AGRG5
Adhesion G-protein coupled receptor G5

1

2

High-throughput

0.407

High

1327690

CTL5
Choline transporter-like protein 5

1

2

High-throughput

0.407

High

1327692

ZNT7
Zinc transporter 7

1

2

High-throughput

0.407

High

1327693

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

2

High-throughput

0.407

High

1327697

CTL1
Choline transporter-like protein 1

1

2

High-throughput

0.407

High

1327699

S39A7
Zinc transporter SLC39A7

1

7

High-throughput

0.407

High

1327701

SL9A6
Sodium/hydrogen exchanger 6

1

2

High-throughput

0.407

High

1327750

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

5

High-throughput

0.407

High

219331

B4GA1
Beta-1,4-glucuronyltransferase 1

2

0

High-throughput

0.328

High

1252893

BAKOR
Beclin 1-associated autophagy-related key regulator

2

0

High-throughput

0.318

High

71515

MEI4
Meiosis-specific protein MEI4

2

0

High-throughput

0.316

High

892226

MCSP
Sperm mitochondrial-associated cysteine-rich protein

2

0

High-throughput

0.316

High

1213955

LCE1D
Late cornified envelope protein 1D

2

0

High-throughput

0.316

High

1214039

LCE1F
Late cornified envelope protein 1F

2

0

High-throughput

0.316

High

1215049

LCE3A
Late cornified envelope protein 3A

2

0

High-throughput

0.316

High

1215183

LCE2C
Late cornified envelope protein 2C

2

0

High-throughput

0.316

High

1235796

KRA57
Keratin-associated protein 5-7

2

0

High-throughput

0.316

High

1257641

KRA52
Keratin-associated protein 5-2

2

0

High-throughput

0.316

High

1327741

CRCT1
Cysteine-rich C-terminal protein 1

2

0

High-throughput

0.316

High

1327713

TM169
Transmembrane protein 169

2

0

High-throughput

0.313

High

1327726

UN93B
Protein unc-93 homolog B1

2

0

High-throughput

0.313

High

133539

ACATN
Acetyl-coenzyme A transporter 1

1

0

High-throughput

0.279

Low

469513

SYPH
Synaptophysin

1

0

High-throughput

0.279

Low

1022425

IDD
Integral membrane protein DGCR2/IDD

1

0

High-throughput

0.279

Low

1195446

NKAI1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1

1

0

High-throughput

0.279

Low

1206207

T255A
Transmembrane protein 255A

1

0

High-throughput

0.279

Low

1213649

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

0

High-throughput

0.279

Low

1327688

F241A
Uncharacterized protein FAM241A

1

0

High-throughput

0.279

Low

1327704

YIPF5
Protein YIPF5

1

0

High-throughput

0.279

Low

877606

CCN3
CCN family member 3

1

0

High-throughput

0.268

Low

1214273

LCE1A
Late cornified envelope protein 1A

1

0

High-throughput

0.251

Low

1215942

LCE5A
Late cornified envelope protein 5A

1

0

High-throughput

0.251

Low

548352

CP2C9
Cytochrome P450 2C9

1

0

High-throughput

0.249

Low

847601

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.249

Low

1027082

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.249

Low

1111607

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.249

Low

1163375

CAH9
Carbonic anhydrase 9

1

0

High-throughput

0.249

Low

1252333

MEX3B
RNA-binding protein MEX3B

1

0

High-throughput

0.249

Low

1293613

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.249

Low

1327689

DHB11
Estradiol 17-beta-dehydrogenase 11

1

0

High-throughput

0.249

Low

1327716

TM237
Transmembrane protein 237

1

0

High-throughput

0.249

Low

1327717

PANX1
Pannexin-1

1

0

High-throughput

0.249

Low

1327722

DERL1
Derlin-1

1

0

High-throughput

0.249

Low

1327724

UNK
RING finger protein unkempt homolog

1

0

High-throughput

0.249

Low

1327725

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.249

Low

1327728

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.249

Low

1327731

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.249

Low

1327732

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.249

Low

1327735

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

1327736

ELOV5
Very long chain fatty acid elongase 5

1

0

High-throughput

0.249

Low

1327738

TM216
Transmembrane protein 216

1

0

High-throughput

0.249

Low

1327739

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

0

High-throughput

0.249

Low

1327757

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

1

0

High-throughput

0.249

Low

230989

TYOBP
TYRO protein tyrosine kinase-binding protein

1

0

High-throughput

0.232

Low

256083

S19A2
Thiamine transporter 1

1

0

High-throughput

0.232

Low

946571

EVA1C
Protein eva-1 homolog C

1

0

High-throughput

0.232

Low

1010496

EREP3
Protein ENTREP3

1

0

High-throughput

0.232

Low

1033386

CDR2
Cerebellar degeneration-related protein 2

1

0

High-throughput

0.232

Low

1158840

VACHT
Vesicular acetylcholine transporter

1

0

High-throughput

0.232

Low

1175877

TM241
UDP-N-acetylglucosamine transporter TMEM241

1

0

High-throughput

0.232

Low

1236221

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.232

Low

1242167

NPAL3
NIPA-like protein 3

1

0

High-throughput

0.232

Low

1291420

RETR3
Reticulophagy regulator 3

1

0

High-throughput

0.232

Low

1313756

S15A3
Solute carrier family 15 member 3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025