Protein: PLS3
Phospholipid scramblase 3 (PL scramblase 3) (Ca(2+)-dependent phospholipid scramblase 3)

Gene: PLS3, PLSCR3
Organism: Homo sapiens
Interactions: 49
UniProt ID: Q9NRY6

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0005509 - calcium ion binding
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1151090

PCH2
Pachytene checkpoint protein 2 homolog

4

1

High-throughput

0.705

High

291870

STK16
Serine/threonine-protein kinase 16

3

1

High-throughput

0.675

High

1337357

CTSR1
Cation channel sperm-associated protein 1

3

1

High-throughput

0.675

High

885429

HXA1
Homeobox protein Hox-A1

2

5

High-throughput

0.606

High

892244

MCSP
Sperm mitochondrial-associated cysteine-rich protein

2

1

High-throughput

0.606

High

1005650

PITX1
Pituitary homeobox 1

2

3

High-throughput

0.606

High

1156062

ZIC1
Zinc finger protein ZIC 1

2

2

High-throughput

0.606

High

1186608

KRA61
Keratin-associated protein 6-1

2

1

High-throughput

0.606

High

1186864

KR196
Keratin-associated protein 19-6

2

1

High-throughput

0.606

High

1186984

KR151
Keratin-associated protein 15-1

2

1

High-throughput

0.606

High

1187929

KR197
Keratin-associated protein 19-7

2

1

High-throughput

0.606

High

1419114

KRA33
Keratin-associated protein 3-3

2

3

High-throughput

0.606

High

1419121

KRA32
Keratin-associated protein 3-2

2

3

High-throughput

0.606

High

276531

PDCD6
Programmed cell death protein 6

1

1

Small-scale

0.601

High

374959

RASH
GTPase HRas

2

6

High-throughput

0.584

High

375993

RASK
GTPase KRas

2

6

High-throughput

0.584

High

833690

NAA10
N-alpha-acetyltransferase 10

2

0

High-throughput

0.580

High

1055280

MTG8
Protein CBFA2T1

2

0

High-throughput

0.580

High

1081491

INCA1
Protein INCA1

2

0

High-throughput

0.580

High

1224916

TENS2
Tensin-2

2

0

High-throughput

0.580

High

1242999

CV039
Synaptic plasticity regulator PANTS

2

0

High-throughput

0.580

High

1307068

KR111
Keratin-associated protein 11-1

2

0

High-throughput

0.580

High

1396241

TNIP3
TNFAIP3-interacting protein 3

2

0

High-throughput

0.580

High

1449019

WWOX
WW domain-containing oxidoreductase

2

0

High-throughput

0.580

High

1449020

AIPL1
Aryl-hydrocarbon-interacting protein-like 1

2

0

High-throughput

0.580

High

159102

LCE2B
Late cornified envelope protein 2B

2

1

High-throughput

0.553

High

1213928

LCE1C
Late cornified envelope protein 1C

2

1

High-throughput

0.553

High

1215130

LCE4A
Late cornified envelope protein 4A

2

1

High-throughput

0.553

High

1215962

LCE5A
Late cornified envelope protein 5A

2

2

High-throughput

0.553

High

180602

PLS1
Phospholipid scramblase 1

1

4

High-throughput

0.541

High

1211373

S1A7B
Protein S100-A7-like 2

1

0

High-throughput

0.493

High

1449018

PLS3
Phospholipid scramblase 3

1

4

High-throughput

0.481

High

1051969

KPCD
Protein kinase C delta type

1

0

Small-scale

0.480

High

133803

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

1

High-throughput

0.479

High

374226

RASN
GTPase NRas

1

6

High-throughput

0.479

High

556367

CADH1
Cadherin-1

1

1

High-throughput

0.479

High

223361

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

845822

MUC18
Cell surface glycoprotein MUC18

1

0

High-throughput

0.458

High

978337

RHOB
Rho-related GTP-binding protein RhoB

1

0

High-throughput

0.458

High

1229102

RNF43
E3 ubiquitin-protein ligase RNF43

1

0

High-throughput

0.458

High

1289652

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1367946

AP2C
Transcription factor AP-2 gamma

1

0

High-throughput

0.438

High

246268

MABP1
Mitogen-activated protein kinase-binding protein 1

2

0

High-throughput

0.316

High

694402

CO8A1
Collagen alpha-1(VIII) chain

2

0

High-throughput

0.316

High

1203504

ACTMP
Actin maturation protease

2

0

High-throughput

0.316

High

1211148

CJ055
Uncharacterized protein C10orf55

2

0

High-throughput

0.316

High

1387672

NXPE2
NXPE family member 2

2

0

High-throughput

0.316

High

1434478

ALG2
Alpha-1,3/1,6-mannosyltransferase ALG2

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025