Protein: FUMH
Fumarate hydratase, mitochondrial (Fumarase) (EC 4.2.1.2)

Gene: FUMH, FUM1
Organism: Saccharomyces cerevisiae S288C
Interactions: 47
UniProt ID: P08417

Gene Ontology (top 5):
GO:0004333 - fumarate hydratase activity
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

469971

HSP77
Import motor subunit, mitochondrial

3

7

High-throughput

0.633

High

469997

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

1

High-throughput

0.584

High

470005

RRP6
Exosome complex exonuclease RRP6

2

1

High-throughput

0.584

High

469996

SSB2
Ribosome-associated molecular chaperone SSB2

2

6

High-throughput

0.552

High

470003

TDA1
Serine/threonine-protein kinase TDA1

1

1

High-throughput

0.536

High

449265

RAD10
DNA repair protein RAD10

1

0

High-throughput

0.513

High

469999

COM1
DNA endonuclease SAE2

1

0

Small-scale

0.504

High

359405

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

2

High-throughput

0.500

High

367653

ENO1
Enolase 1

1

3

High-throughput

0.500

High

469973

G6PI
Glucose-6-phosphate isomerase

1

1

High-throughput

0.500

High

469993

KOG1
Target of rapamycin complex 1 subunit KOG1

1

3

High-throughput

0.481

High

469976

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.479

High

470007

SMC6
Structural maintenance of chromosomes protein 6

1

0

High-throughput

0.479

High

359116

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

2

High-throughput

0.479

High

368384

TPIS
Triosephosphate isomerase

1

1

High-throughput

0.479

High

392036

HSP82
ATP-dependent molecular chaperone HSP82

1

5

High-throughput

0.479

High

454630

PUT2
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial

1

3

High-throughput

0.479

High

469974

HSC82
ATP-dependent molecular chaperone HSC82

1

5

High-throughput

0.479

High

469975

ACON
Aconitate hydratase, mitochondrial

1

3

High-throughput

0.479

High

469977

SIS1
Protein SIS1

1

4

High-throughput

0.479

High

469978

CDC48
Cell division control protein 48

1

2

High-throughput

0.479

High

469979

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

469980

BMH1
Protein BMH1

1

2

High-throughput

0.479

High

469981

HS104
Heat shock protein 104

1

2

Small-scale

0.479

High

469983

HOG1
Mitogen-activated protein kinase HOG1

1

1

High-throughput

0.479

High

469986

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.479

High

469987

TSA1
Peroxiredoxin TSA1

1

3

High-throughput

0.479

High

469988

GLYC
Serine hydroxymethyltransferase, cytosolic

1

1

High-throughput

0.479

High

469990

ATG8
Autophagy-related protein 8

1

1

High-throughput

0.479

High

469995

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

469998

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

1

2

High-throughput

0.479

High

470001

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.479

High

470002

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

2

High-throughput

0.479

High

439066

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

0

High-throughput

0.458

High

448504

RHO1
GTP-binding protein RHO1

1

0

High-throughput

0.458

High

469982

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

469984

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

0

High-throughput

0.458

High

469985

YPT7
Ypt/Rab-type GTPase YPT7

1

0

Small-scale

0.458

High

469991

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.458

High

469992

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.458

High

469994

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

470004

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

High-throughput

0.458

High

469972

HSP71
Heat shock protein SSA1

1

5

High-throughput

0.445

High

470000

TAM41
Phosphatidate cytidylyltransferase, mitochondrial

1

0

High-throughput

0.438

High

469989

NU170
Nucleoporin NUP170

1

2

High-throughput

0.437

High

470006

DBP10
ATP-dependent RNA helicase DBP10

1

1

High-throughput

0.437

High

470008

ENV10
SRP-independent targeting protein 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025