Protein: TDA1
Serine/threonine-protein kinase TDA1 (Topoisomerase I damage affected protein 1) (EC 2.7.11.1)

Gene: TDA1
Organism: Saccharomyces cerevisiae S288C
Interactions: 42
UniProt ID: Q03533

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004683 - calcium/calmodulin-dependent protein kinase activity
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

800626

RIM11
Serine/threonine-protein kinase RIM11/MSD1

2

20

High-throughput

0.812

High

909763

YPT32
GTP-binding protein YPT32/YPT11

1

4

High-throughput

0.648

High

364717

CDK1
Cyclin-dependent kinase 1

1

14

High-throughput

0.647

High

656856

KC12
Casein kinase I homolog 2

1

16

High-throughput

0.647

High

801911

KSP1
Serine/threonine-protein kinase KSP1

1

18

High-throughput

0.647

High

865536

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

18

High-throughput

0.647

High

1040416

FRK1
Fatty acyl-CoA synthetase and RNA processing-associated kinase 1

1

19

High-throughput

0.647

High

1043336

ARP8
Actin-like protein ARP8

1

8

High-throughput

0.647

High

438222

CDC37
Hsp90 co-chaperone Cdc37

1

10

High-throughput

0.618

High

735547

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

19

High-throughput

0.618

High

779634

VPS21
Vacuolar protein sorting-associated protein 21

1

7

High-throughput

0.579

High

656348

PP2B1
Serine/threonine-protein phosphatase 2B catalytic subunit A1

1

10

Small-scale

0.536

High

470003

FUMH
Fumarate hydratase, mitochondrial

1

1

High-throughput

0.536

High

635046

VPS33
Vacuolar protein sorting-associated protein 33

1

2

High-throughput

0.536

High

910771

SKP1
Suppressor of kinetochore protein 1

1

3

High-throughput

0.536

High

1043335

DIN7
DNA damage-inducible protein DIN7

1

2

High-throughput

0.515

High

557030

AAKG
5'-AMP-activated protein kinase subunit gamma

1

14

High-throughput

0.508

High

416567

HXKB
Hexokinase-2

1

3

Small-scale

0.501

High

575609

PP2B2
Serine/threonine-protein phosphatase 2B catalytic subunit A2

1

10

Small-scale

0.501

High

661434

PSA3
Proteasome subunit alpha type-3

1

6

High-throughput

0.501

High

701604

UBC8
Ubiquitin-conjugating enzyme E2-24 kDa

1

13

High-throughput

0.501

High

818390

RTR1
RNA polymerase II subunit B1 CTD phosphatase RTR1

1

1

High-throughput

0.501

High

416474

HXKA
Hexokinase-1

1

3

High-throughput

0.500

High

1043333

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

1

High-throughput

0.500

High

610194

PDI
Protein disulfide-isomerase

1

5

High-throughput

0.489

High

746756

KPR1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.480

High

1043332

IWR1
RNA polymerase II nuclear localization protein IWR1

1

0

High-throughput

0.480

High

708029

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

709957

BMH1
Protein BMH1

1

20

High-throughput

0.479

High

760342

BMH2
Protein BMH2

1

20

High-throughput

0.479

High

1043330

RUVB1
RuvB-like protein 1

1

2

High-throughput

0.479

High

1043334

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

2

High-throughput

0.479

High

865729

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

836091

COPB2
Coatomer subunit beta'

1

3

High-throughput

0.457

High

555144

G6PI
Glucose-6-phosphate isomerase

1

1

High-throughput

0.457

High

524987

HSP71
Heat shock protein SSA1

1

12

High-throughput

0.445

High

546082

SSB1
Ribosome-associated molecular chaperone SSB1

1

12

High-throughput

0.445

High

742286

HSP7F
Heat shock protein homolog SSE1

1

19

High-throughput

0.445

High

819651

SSB2
Ribosome-associated molecular chaperone SSB2

1

12

High-throughput

0.445

High

739749

SPT16
FACT complex subunit SPT16

1

2

High-throughput

0.437

High

1043331

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

10

High-throughput

0.407

High

454232

LEUC
3-isopropylmalate dehydratase

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025