Protein: ACE2
Metallothionein expression activator

Gene: ACE2
Organism: Saccharomyces cerevisiae S288C
Interactions: 47
UniProt ID: P21192

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 - cis-regulatory region sequence-specific DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

636473

CBK1
Serine/threonine-protein kinase CBK1

6

4

Small-scale

0.950

High

364324

CDK1
Cyclin-dependent kinase 1

6

6

Small-scale

0.947

High

636455

XPO1
Exportin-1

4

16

Small-scale

0.696

High

602313

PHO85
Cyclin-dependent protein kinase PHO85

1

7

Small-scale

0.647

High

636449

MCK1
Protein kinase MCK1

1

8

High-throughput

0.647

High

636464

KSP1
Serine/threonine-protein kinase KSP1

1

4

High-throughput

0.647

High

636448

ACE2
Metallothionein expression activator

1

19

High-throughput

0.621

High

636451

CG23
G2/mitotic-specific cyclin-3

2

5

Small-scale

0.611

High

636476

CDC14
Tyrosine-protein phosphatase CDC14

2

6

Small-scale

0.611

High

636478

HDA2
HDA1 complex subunit 2

2

0

High-throughput

0.570

High

636454

TF2B
Transcription initiation factor IIB

1

5

Small-scale

0.561

High

628037

FKBP
FK506-binding protein 1

1

1

High-throughput

0.515

High

636456

IMB3
Importin subunit beta-3

1

1

High-throughput

0.515

High

636460

RRP1
Ribosomal RNA-processing protein 1

1

4

High-throughput

0.515

High

636471

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

16

High-throughput

0.515

High

416369

HXKA
Hexokinase-1

1

0

High-throughput

0.493

High

636472

RTC4
Restriction of telomere capping protein 4

1

0

High-throughput

0.493

High

636474

IGO1
mRNA stability protein IGO1

1

0

High-throughput

0.486

High

636459

GSP2
GTP-binding nuclear protein GSP2/CNR2

1

6

Small-scale

0.481

High

636466

KOG1
Target of rapamycin complex 1 subunit KOG1

1

5

High-throughput

0.481

High

578833

HSC82
ATP-dependent molecular chaperone HSC82

1

5

High-throughput

0.479

High

632402

CG12
G1/S-specific cyclin CLN2

1

7

Small-scale

0.479

High

636450

CG22
G2/mitotic-specific cyclin-2

1

5

Small-scale

0.479

High

636461

SPT10
Protein SPT10

1

1

High-throughput

0.479

High

636463

AMN1
Antagonist of mitotic exit network protein 1

1

9

Small-scale

0.479

High

636467

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.479

High

636479

VAM6
Vacuolar morphogenesis protein 6

1

2

High-throughput

0.479

High

636480

SCC1
Sister chromatid cohesion protein 1

1

2

High-throughput

0.479

High

636468

MOB2
CBK1 kinase activator protein MOB2

1

0

Small-scale

0.460

High

636482

CAF1A
Chromatin assembly factor 1 subunit A

1

0

High-throughput

0.460

High

448281

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

0

High-throughput

0.458

High

636469

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

636462

ANM1
Protein arginine N-methyltransferase 1

1

3

High-throughput

0.457

High

481478

HSP73
Heat shock protein SSA3

1

10

High-throughput

0.445

High

523041

HSP71
Heat shock protein SSA1

1

10

High-throughput

0.445

High

525905

HSP72
Heat shock protein SSA2

1

10

High-throughput

0.445

High

543798

SSB1
Ribosome-associated molecular chaperone SSB1

1

8

High-throughput

0.445

High

636452

SIS1
Protein SIS1

1

8

High-throughput

0.445

High

636453

MAS5
Mitochondrial protein import protein MAS5

1

6

High-throughput

0.445

High

636457

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

636458

HSP79
Heat shock protein homolog SSE2

1

20

High-throughput

0.445

High

636465

SSZ1
Ribosome-associated complex subunit SSZ1

1

7

High-throughput

0.445

High

636475

PFD4
Prefoldin subunit 4

1

1

High-throughput

0.445

High

636477

NSE5
Non-structural maintenance of chromosome element 5

1

0

High-throughput

0.438

High

636481

HSP42
Heat shock protein 42

1

0

High-throughput

0.426

High

636470

NUP42
Nucleoporin NUP42

1

0

Small-scale

0.251

Low


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Last updated: 11Aug2025