Protein: CLC1
Clathrin light chain (CLC)

Gene: CLC1
Organism: Saccharomyces cerevisiae S288C
Interactions: 59
UniProt ID: P17891

Gene Ontology (top 5):
GO:0005198 - structural molecule activity
GO:0005516 - calmodulin binding
GO:0005802 - trans-Golgi network
GO:0005886 - plasma membrane
GO:0006886 - intracellular protein transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

609204

CLH
Clathrin heavy chain

13

7

Small-scale

0.981

High

609213

SLA2
Protein SLA2

4

10

Small-scale

0.694

High

609220

GGA2
ADP-ribosylation factor-binding protein GGA2

3

9

Small-scale

0.640

High

609244

SWA2
Auxilin-like clathrin uncoating factor SWA2

2

4

Small-scale

0.601

High

609231

ENT3
Epsin-3

2

8

Small-scale

0.584

High

609241

ENT5
Epsin-5

2

8

Small-scale

0.584

High

522987

HSP71
Heat shock protein SSA1

2

7

High-throughput

0.571

High

609221

AP18A
Clathrin coat assembly protein AP180A

1

10

Small-scale

0.561

High

609214

SPT7
SAGA complex subunit SPT7

1

1

High-throughput

0.536

High

609232

SGF73
SAGA complex subunit SGF73

1

0

High-throughput

0.513

High

609205

NPR1
Nitrogen permease reactivator protein

1

1

High-throughput

0.501

High

609208

HRR25
Casein kinase I homolog HRR25

1

1

High-throughput

0.501

High

609211

PAN1
Actin cytoskeleton-regulatory complex protein PAN1

1

8

Small-scale

0.501

High

609223

END3
Actin cytoskeleton-regulatory complex protein END3

1

9

Small-scale

0.501

High

609233

AP18B
Clathrin coat assembly protein AP180B

1

10

Small-scale

0.501

High

609250

PKH2
Serine/threonine-protein kinase PKH2

1

1

High-throughput

0.501

High

609252

LAS17
Proline-rich protein LAS17

1

2

High-throughput

0.489

High

609226

GTS1
Protein GTS1

1

4

Small-scale

0.481

High

609203

CLC1
Clathrin light chain

1

3

High-throughput

0.479

High

609215

AP1S1
AP-1 complex subunit sigma-1

1

4

Small-scale

0.479

High

609217

AP1B1
AP-1 complex subunit beta-1

1

12

Small-scale

0.479

High

609246

AP3D
AP-3 complex subunit delta

1

14

High-throughput

0.479

High

584335

GCN2
eIF-2-alpha kinase GCN2

1

2

High-throughput

0.470

High

359141

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

0

High-throughput

0.458

High

560271

KEX2
Kexin

1

0

Small-scale

0.458

High

609236

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.458

High

609249

CHS5
Chitin biosynthesis protein CHS5

1

0

Small-scale

0.458

High

602304

PHO85
Cyclin-dependent protein kinase PHO85

1

1

High-throughput

0.457

High

609210

MKK1
MAP kinase kinase MKK1/SSP32

1

1

High-throughput

0.457

High

609212

SWE1
Mitosis inhibitor protein kinase SWE1

1

1

High-throughput

0.457

High

609229

IKS1
Probable serine/threonine-protein kinase IKS1

1

2

High-throughput

0.457

High

609234

SSK2
MAP kinase kinase kinase SSK2

1

1

High-throughput

0.457

High

609238

FRK1
Fatty acyl-CoA synthetase and RNA processing-associated kinase 1

1

4

High-throughput

0.457

High

609209

VPS10
Vacuolar protein sorting/targeting protein VPS10

1

1

Small-scale

0.437

High

609219

ATG8
Autophagy-related protein 8

1

2

Small-scale

0.437

High

609239

TOM1
E3 ubiquitin-protein ligase TOM1

1

1

High-throughput

0.437

High

609245

SMC5
Structural maintenance of chromosomes protein 5

1

4

High-throughput

0.407

High

609247

CWC2
Pre-mRNA-splicing factor CWC2

1

3

High-throughput

0.407

High

609206

SGF29
SAGA complex subunit SGF29

1

0

High-throughput

0.279

Low

609237

ADA2
SAGA complex subunit ADA2

1

0

High-throughput

0.279

Low

609253

SUS1
SAGA complex subunit SUS1

1

0

High-throughput

0.279

Low

575376

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.269

Low

609218

FRMSR
Free methionine-R-sulfoxide reductase

1

0

High-throughput

0.269

Low

609225

BMT5
25S rRNA

1

0

High-throughput

0.269

Low

609227

TOS3
Serine/threonine-protein kinase TOS3

1

0

High-throughput

0.261

Low

609228

CTK2
CTD kinase subunit beta

1

0

High-throughput

0.261

Low

394207

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.249

Low

609207

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

609216

DEF1
RNA polymerase II degradation factor 1

1

0

High-throughput

0.249

Low

609230

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

609243

SEC10
Exocyst complex component SEC10

1

0

Small-scale

0.249

Low

609251

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.249

Low

609222

SPT8
SAGA complex subunit SPT8

1

0

High-throughput

0.232

Low

609224

TCPB
T-complex protein 1 subunit beta

1

0

High-throughput

0.232

Low

609235

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.232

Low

609240

GCN5
Histone acetyltransferase GCN5

1

0

High-throughput

0.232

Low

609242

NSE3
Non-structural maintenance of chromosome element 3

1

0

High-throughput

0.232

Low

609248

HFI1
SAGA complex subunit HFI1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025