Protein: TFC5
Transcription factor TFIIIB component B'' (TFIIIB90)

Gene: TFC5, BDP1
Organism: Saccharomyces cerevisiae S288C
Interactions: 45
UniProt ID: P46678

Gene Ontology (top 5):
GO:0000126 - transcription factor TFIIIB complex
GO:0000995 - RNA polymerase III general transcription initiation factor activity
GO:0001112 - DNA-templated transcription open complex formation
GO:0001156 - TFIIIC-class transcription factor complex binding
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

708757

TF3B
Transcription factor IIIB 70 kDa subunit

8

2

Small-scale

0.966

High

561494

TBP
TATA-box-binding protein

4

2

Small-scale

0.896

High

751900

TFC4
Transcription factor tau 131 kDa subunit

6

0

Small-scale

0.701

High

647152

RPC2
DNA-directed RNA polymerase III subunit RPC2

3

1

Small-scale

0.640

High

402228

RPC1
DNA-directed RNA polymerase III subunit RPC1

2

1

High-throughput

0.601

High

781681

RPC5
DNA-directed RNA polymerase III subunit RPC5

3

1

Small-scale

0.585

High

735044

RPC3
DNA-directed RNA polymerase III subunit RPC3

2

0

High-throughput

0.559

High

707463

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.553

High

858493

SUB1
RNA polymerase II transcriptional coactivator SUB1

1

0

Small-scale

0.480

High

459120

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

1

High-throughput

0.479

High

632179

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

1

High-throughput

0.479

High

632269

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

1

High-throughput

0.479

High

700016

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

1

High-throughput

0.479

High

748137

RPC6
DNA-directed RNA polymerase III subunit RPC6

1

1

High-throughput

0.479

High

776304

RPC8
DNA-directed RNA polymerase III subunit RPC8

1

1

High-throughput

0.479

High

823713

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

1

High-throughput

0.479

High

382182

H4
Histone H4

1

0

High-throughput

0.458

High

609195

RPC7
DNA-directed RNA polymerase III subunit RPC7

1

0

High-throughput

0.458

High

645069

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

0

High-throughput

0.458

High

674419

RPC4
DNA-directed RNA polymerase III subunit RPC4

1

0

High-throughput

0.458

High

735788

TFC1
Transcription factor tau 95 kDa subunit

1

0

High-throughput

0.458

High

757405

TFC3
Transcription factor tau 138 kDa subunit

1

0

Small-scale

0.458

High

792852

ANM1
Protein arginine N-methyltransferase 1

1

0

Small-scale

0.458

High

858491

RPC9
DNA-directed RNA polymerase III subunit RPC9

1

0

High-throughput

0.458

High

858496

RPC10
DNA-directed RNA polymerase III subunit RPC10

1

0

High-throughput

0.458

High

858497

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

646449

RAD53
Serine/threonine-protein kinase RAD53

1

1

High-throughput

0.437

High

381152

H2B1
Histone H2B.1

1

0

High-throughput

0.426

High

781759

SET3
SET domain-containing protein 3

1

0

High-throughput

0.426

High

858494

H3
Histone H3

1

0

High-throughput

0.426

High

524354

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.407

High

527012

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.407

High

545341

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.407

High

741840

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.407

High

819098

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.407

High

858495

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

1

High-throughput

0.407

High

548912

SCH9
Serine/threonine-protein kinase SCH9

1

0

Small-scale

0.261

Low

461026

MOD5
tRNA dimethylallyltransferase

1

0

Small-scale

0.249

Low

858492

TAF6
SAGA complex/transcription factor TFIID complex subunit TAF6

1

0

High-throughput

0.249

Low

858500

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.249

Low

676111

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.232

Low

736672

ASF1
Histone chaperone ASF1

1

0

High-throughput

0.232

Low

804254

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.232

Low

858498

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

0

High-throughput

0.232

Low

858499

CAF1A
Chromatin assembly factor 1 subunit A

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025